Results 71 to 80 of about 39,677 (234)
Why do axons differ in caliber? [PDF]
, 2012 CNS axons differ in diameter (d) by nearly 100-fold (∼0.1-10 μm); therefore, they differ in cross-sectional area (d(2)) and volume by nearly 10,000-fold.
Balasubramanian, Vijay +4 more
core +2 more sources
The Transduction Cascade in Retinal ON-Bipolar Cells: Signal Processing and Disease [PDF]
Annual Review of Vision Science, 2017 Our robust visual experience is based on the reliable transfer of information from our photoreceptor cells, the rods and cones, to higher brain centers. At the very first synapse of the visual system, information is split into two separate pathways, ON and OFF, which encode increments and decrements in light intensity, respectively.
Martemyanov, Kirill A +1 more
openaire +4 more sources
Advanced Science, EarlyView.Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska +14 more
wiley +1 more source
Inhibitory control of feature selectivity in an object motion sensitive circuit of the retina [PDF]
, 2017 Object motion sensitive (OMS) W3-retinal ganglion cells (W3-RGCs) in mice respond to local movements in a visual scene but remain silent during self-generated global image motion. The excitatory inputs that drive responses of W3-RGCs to local motion were
Kerschensteiner, Daniel, Kim, Tahnbee
core +3 more sources
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
Rod photoreceptors drive circadian photoentrainment across a wide range of light intensities. [PDF]
, 2010 In mammals, synchronization of the circadian pacemaker in the hypothalamus is achieved through direct input from the eyes conveyed by intrinsically photosensitive retinal ganglion cells (ipRGCs).
Alam, Nazia M +6 more
core
Irregular S-cone mosaics in felid retinas: spatial interaction with axonless horizontal revealed by cross-correlation [PDF]
, 2000 In most mammals short-wavelength-sensitive (S) cones are arranged in irregular patterns with widely variable intercell distances. Consequently, mosaics of connected interneurons either may show some type of correlation to photoreceptor placement or may ...
Ahnelt +52 more
core +1 more source
Interneuron Circuits Tune Inhibition in Retinal Bipolar Cells
Journal of Neurophysiology, 2010 While connections between inhibitory interneurons are common circuit elements, it has been difficult to define their signal processing roles because of the inability to activate these circuits using natural stimuli. We overcame this limitation by studying connections between inhibitory amacrine cells in the retina.
Erika D, Eggers, Peter D, Lukasiewicz
openaire +3 more sources
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Timing the generation of distinct retinal cells by homeobox proteins.
PLoS Biology, 2006 The reason why different types of vertebrate nerve cells are generated in a particular sequence is still poorly understood. In the vertebrate retina, homeobox genes play a crucial role in establishing different cell identities.
Sarah Decembrini +4 more
doaj +1 more source