Results 21 to 30 of about 39,677 (234)
Molecular Therapy: Methods & Clinical Development, 2020 The loss of photoreceptors in individuals with retinal degenerative diseases leads to partial or complete blindness. Optogenetic therapy is a promising approach for restoring vision to the blind.
Qi Lu +4 more
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Identification of autoantibodies against TRPM1 in patients with paraneoplastic retinopathy associated with ON bipolar cell dysfunction. [PDF]
PLoS ONE, 2011 Paraneoplastic retinopathy (PR), including cancer-associated retinopathy (CAR) and melanoma-associated retinopathy (MAR), is a progressive retinal disease caused by antibodies generated against neoplasms not associated with the eye.
Mineo Kondo +10 more
doaj +1 more source
Axonal synapses utilize multiple synaptic ribbons in the mammalian retina. [PDF]
PLoS ONE, 2012 In the mammalian retina, bipolar cells and ganglion cells which stratify in sublamina a of the inner plexiform layer (IPL) show OFF responses to light stimuli while those that stratify in sublamina b show ON responses.
Hong-Lim Kim +8 more
doaj +1 more source
Birth of cone bipolar cells, but not rod bipolar cells, is associated with existing RGCs.
PLoS ONE, 2014 Retinal ganglion cells (RGCs) play important roles in retinogenesis. They are required for normal retinal histogenesis and retinal cell number balance.
Ling Bai +3 more
doaj +1 more source
Developmental errors in the common marmoset retina
Frontiers in Neuroanatomy, 2022 Although retinal organization is remarkably conserved, morphological anomalies can be found to different extents and varieties across animal species with each presenting unique characteristics and patterns of displaced and misplaced neurons.
Silke Haverkamp +3 more
doaj +1 more source
RdgB2 is required for dim-light input into intrinsically photosensitive retinal ganglion cells. [PDF]
, 2015 A subset of retinal ganglion cells is intrinsically photosensitive (ipRGCs) and contributes directly to the pupillary light reflex and circadian photoentrainment under bright-light conditions.
Berson, David M +8 more
core +2 more sources
Transient calcium current of retinal bipolar cells of the mouse [PDF]
Neuroscience Research Supplements, 1989 1. Isolated bipolar cells were obtained by enzymic (papain) dissociation of the adult mouse retina. The membrane voltage was clamped and the membrane currents were measured by the whole‐cell version of the patch‐clamp technique. Isolated bipolar cells and horizontal cells of the goldfish retina were also studied for comparison. 2.
A, Kaneko, L H, Pinto, M, Tachibana
openaire +3 more sources
Mitochondrial Protection by Exogenous Otx2 in Mouse Retinal Neurons
Cell Reports, 2015 OTX2 (orthodenticle homeobox 2) haplodeficiency causes diverse defects in mammalian visual systems ranging from retinal dysfunction to anophthalmia. We find that the retinal dystrophy of Otx2+/GFP heterozygous knockin mice is mainly due to the loss of ...
Hyoung-Tai Kim +19 more
doaj +1 more source
Extracellular lactate as an alternative energy source for retinal bipolar cells. [PDF]
J Biol ChemRetinal bipolar and amacrine cells receive visual information from photoreceptors and participate in the first steps of image processing in the retina. Several studies have suggested the operation of aerobic glycolysis and a lactate shuttle system in the retina due to the high production of this metabolite under aerobic conditions.
Calbiague-Garcia V +5 more
europepmc +3 more sources
Cells, 2022 Retinal degeneration is a common feature in peroxisomal disorders leading to blindness. Peroxisomes are present in the different cell types of the retina; however, their precise contribution to retinal integrity is still unclear.
Daniëlle Swinkels +7 more
doaj +1 more source