Results 31 to 40 of about 11,427 (180)

Computational modeling of retinal hypoxia and photoreceptor degeneration in patients with age-related macular degeneration.

PLoS ONE, 2019
Although drusen have long been acknowledged as a primary hallmark of dry age-related macular degeneration (AMD) their role in the disease remains unclear.
Kevin J McHugh, Dian Li, Jay C Wang, Leon Kwark, Jessica Loo, Venkata Macha, Sina Farsiu, Leo A Kim, Magali Saint-Geniez   +8 more
doaj   +1 more source

A Case of a Young Asymptomatic Woman with Optic Disc Drusen and Vasculitis

Case Reports in Ophthalmology, 2011
Purpose: We present the case of a young woman with optic disc drusen and peripheral vasculitis. Methods: Diagnosis was based on fundoscopic, optical coherence tomography as well as fluorescein angiography (FA) findings.
Tryfon Rotsos, Chrysanthos Symeonidis, Mrinal Rana, James S. Deane   +3 more
doaj   +1 more source

Characterization of retinal pigment epithelium layer in healthy and diseased retinas with high‐resolution adaptive optics transscleral flood illumination imaging

Acta Ophthalmologica, EarlyView.
Abstract Purpose The retinal pigment epithelium (RPE) is critical in the pathophysiology of retinal diseases, such as age‐related macular degeneration. Adaptive optics transscleral flood illumination (AO‐TFI) offers rapid, detailed morphometric characterization of the RPE layer.
Leila Sara Eppenberger, Safa Mohanna, Sohrab Ferdowsi, Sonja Simon‐Zoula, Oliver Pfäffli, Christoph Amstutz, Lucas M. Bachmann, Michael A. Thiel, Martin K. Schmid   +8 more
wiley   +1 more source

Generation of iPSCs (RFSCi007-A, RFSCi008-A) from a patient with early-onset bilateral drusen and a healthy sibling for retinal disease modeling

Stem Cell Research
Drusen are extracellular deposits between the retinal pigment epithelium and Bruch’s membrane, commonly linked to age-related macular degeneration (AMD).
Sonali Singh, Wendy Runyon, Sam Hu, Paige Grona Kennedy, Ajeet Singh, Rinki Ratnapriya, Ritu Kumar, Karl Csaky, Srinivasa R. Sripathi   +8 more
doaj   +1 more source

The prechoroidal cleft in neovascular age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract The prechoroidal cleft is a lenticular, hypo‐reflective space on optical coherence tomography imaging, located between a band of fibrovascular material underneath the retinal pigment epithelium (RPE) and Bruch's membrane. It occurs in 8%–22% of neovascular age‐related macular degeneration (nAMD) eyes, most often with macular neovascularization
Niels J. Brouwer, T. H. Khanh Vu, Yvonne De Jong‐Hesse, Elon H. C. van Dijk   +3 more
wiley   +1 more source

Revised Swedish visual field standards for a driver's licence: Threshold perimetry as a predictor of eligibility according to the current Swedish and current Norwegian suprathreshold standards

Acta Ophthalmologica, EarlyView.
Abstract Purpose To explore whether threshold perimetry can predict fulfilment of the current Swedish and current Norwegian Esterman perimetry standards for Group 1 driver's licence, and differences in compliance between the former and current Swedish visual field standards.
Wid Saadi, Tomas Bro, Susanna Sagerfors
wiley   +1 more source

Significance of Hyperreflective Foci as an Optical Coherence Tomography Biomarker in Retinal Diseases: Characterization and Clinical Implications

Journal of Ophthalmology, 2021
Hyperreflective foci (HRF) is a term coined to depict hyperreflective dots or roundish lesions within retinal layers visualized through optical coherence tomography (OCT).
Serena Fragiotta, Solmaz Abdolrahimzadeh, Rosa Dolz-Marco, Yoichi Sakurada, Orly Gal-Or, Gianluca Scuderi   +5 more
doaj   +1 more source

OCT Based Interpretation of the Optic Nerve Head Anatomy and Prevalence of Optic Disc Drusen in Patients with Idiopathic Intracranial Hypertension (IIH)

Life, 2021
We aimed to systematically examine the optic nerve head anatomy in patients with idiopathic intracranial hypertension (IIH) using a standardized optical coherence tomography (OCT) protocol.
Elisabeth Arnberg Wibroe, Lasse Malmqvist, Steffen Hamann   +2 more
doaj   +1 more source

Age distribution and characteristics of choroidal nevi in 35 559 individuals: A nationwide study using optometry fundus photography

Acta Ophthalmologica, EarlyView.
Abstract Purpose To examine the age distribution and characteristics of choroidal nevi in a large nationwide sample. Methods We included all individuals who underwent fundus photography in a nationwide chain of optometry stores during a 5‐week period in 2023.
Carsten Faber, Hibba Quhill, Danson Muttuvelu, Jens Folke Kiilgaard   +3 more
wiley   +1 more source

Laser photocoagulation of soft macular drusen

Офтальмохирургия, 2013
Purpose. The assessment of morphological and functional results of the threshold photocoagulation in eyes with large soft macular drusen. Material and methods. Thirty four patients (39 eyes) were enrolled in the study.
L.I. Balashevich, M.V. Gatsu, M.V. Gordeyeva   +2 more
doaj