Results 91 to 100 of about 286,988 (401)
Signal transmission through the dark-adapted retina of the toad (Bufo marinus). Gain, convergence, and signal/noise. [PDF]
, 1990 Responses to light were recorded from rods, horizontal cells, and ganglion cells in dark-adapted toad eyecups. Sensitivity was defined as response amplitude per isomerization per rod for dim flashes covering the excitatory receptive field centers.
Copenhagen, David, Hemilä, S, Reuter, T
core +2 more sources
Genetics‐Based Targeting Strategies for Precise Neuromodulation
Advanced Science, EarlyView.In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He +11 more
wiley +1 more source
VEGFD Protects Retinal Ganglion Cells and, consequently, Capillaries against Excitotoxic Injury
Molecular Therapy: Methods & Clinical Development, 2020 In the central nervous system, neurons and the vasculature influence each other. While it is well described that a functional vascular system is trophic to neurons and that vascular damage contributes to neurodegeneration, the opposite scenario in which ...
Annabelle Schlüter +4 more
doaj
Journal of Neuroinflammation, 2023 Background Optic nerve injury (ONI) is a key cause of irreversible blindness and triggers retinal ganglion cells (RGCs) change and synapse loss. Microglia is the resistant immune cell in brain and retina and has been demonstrated to be highly related ...
Ke Yao +9 more
doaj +1 more source
Effects of Iron and Zinc on Mitochondria: Potential Mechanisms of Glaucomatous Injury
Frontiers in Cell and Developmental Biology, 2021 Glaucoma is the most substantial cause of irreversible blinding, which is accompanied by progressive retinal ganglion cell damage. Retinal ganglion cells are energy-intensive neurons that connect the brain and retina, and depend on mitochondrial ...
Jiahui Tang, Yehong Zhuo, Yiqing Li
doaj +1 more source
SpikeSEE: An Energy-Efficient Dynamic Scenes Processing Framework for Retinal Prostheses [PDF]
arXiv, 2022 Intelligent and low-power retinal prostheses are highly demanded in this era, where wearable and implantable devices are used for numerous healthcare applications. In this paper, we propose an energy-efficient dynamic scenes processing framework (SpikeSEE) that combines a spike representation encoding technique and a bio-inspired spiking recurrent ...
arxiv
Non-viral delivery and optimized optogenetic stimulation of retinal ganglion cells led to behavioral restoration of vision [PDF]
, 2012 Stimulation of retinal neurons using optogenetics via use of chanelrhodopsin-2 (ChR2) has opened up a new direction for restoration of vision for treatment of retinitis pigmentosa (RP).
Edward Wong +5 more
core +2 more sources
Advanced Science, EarlyView.Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang +4 more
wiley +1 more source
Optogenetic restoration of retinal ganglion cell activity in the living primate
Nature Communications, 2020 Optogenetic therapies for vision restoration aim to confer intrinsic light sensitivity to retinal ganglion cells when photoreceptors have degenerated and light sensitivity has been irreversibly lost. We combine adaptive optics ophthalmoscopy with calcium
Juliette E. McGregor +8 more
semanticscholar +1 more source
The eyes of suckermouth armoured catfish (Loricariidae, subfamily Hypostomus): pupil response, lenticular longitudinal spherical aberration and retinal topography [PDF]
, 2002 The dilated, round pupils of a species of suckermouth armoured catfish (Liposarcus pardalis) constrict slowly on illumination (over 35-40 min) to form crescent-shaped apertures. Ray tracing of He-Ne laser beams shows that the lenses of a related species (
Collin, S. P. +2 more
core