Results 111 to 120 of about 15,573 (263)

Melanopsin mediates retrograde visual signaling in the retina.

open access: yesPLoS ONE, 2012
The canonical flow of visual signals proceeds from outer to inner retina (photoreceptors → bipolar cells → ganglion cells). However, melanopsin-expressing ganglion cells are photosensitive and functional sustained light signaling to retinal dopaminergic ...
Dao-Qi Zhang   +4 more
doaj   +1 more source

Berberine alleviates pyroptosis of retinal ganglion cells in diabetic retinopathy by regulating AKT1, JUN, and STAT3

open access: yesIbrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li   +7 more
wiley   +1 more source

Bio‐inspired artificial retina with receptive fields for in‐sensor multiply‐and‐accumulate operations

open access: yesInfoMat, EarlyView.
We developed a bio‐inspired artificial retina in which curved artificial receptive fields composed of perovskite photoconductors perform multiply‐and‐accumulate operations through in‐sensor computing. This architecture simultaneously realized the structural efficiency of human eyes (compact single‐lens imaging system) and functional advantages of ...
Jisang Ha   +8 more
wiley   +1 more source

Effects of tACS-Like Electrical Stimulation on Correlated Firing of Retinal Ganglion Cells: Part III

open access: yesEye and Brain, 2022
Franklin R Amthor, Christianne E Strang Department of Psychology, The University of Alabama at Birmingham, Birmingham, AL, 35294, USACorrespondence: Franklin R AmthorDepartment of Psychology, The University of Alabama at Birmingham, 1300 University Blvd,
Amthor FR, Strang CE
doaj  

Neuroprotective effects of erythropoietin on rat retinas subjected to oligemia

open access: yesClinics, 2018
OBJECTIVES: Erythropoietin may have neuroprotective potential after ischemia of the central nervous system. Here, we conducted a study to characterize the protective effects of erythropoietin on retinal ganglion cells and gliotic reactions in an ...
Litia Alves de Carvalho   +7 more
doaj   +1 more source

Co-ordinating retinal histogenesis: early cell cycle exit enhances early cell fate determination in the Xenopus retina

open access: yes, 2002
The laminar arrays of distinct cell types in the vertebrate retina are built by a histogenic process in which cell fate is correlated with birth order.
Philpott, A.   +4 more
core  

Retrograde degeneration of retinal ganglion cells in homonymous hemianopsia

open access: yes, 2015
Angela M Herro, Byron L Lam Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL, USA Background: The aim of this study was to demonstrate the relationship between topographic reduction
Herro AM   +3 more
core   +1 more source

Ex Vivo Evaluation of Poly(Solketal Acrylate) Nanoparticles for Intravitreal Drug Delivery to the Posterior Eye Segment

open access: yesMacromolecular Rapid Communications, EarlyView.
Nile Red‐loaded poly(solketal acrylate) nanoparticles enable fluorescence tracking and exhibit nontoxic profiles in retinal cells. Enhanced cellular uptake and deep retinal penetration after intravitreal injection highlight their excellent potential for targeted ocular drug delivery to the posterior segment of the eye.
Yasaman Pourdakheli Hamedani   +6 more
wiley   +1 more source

Functional and cell-specific regulation of the Brn-3b transcription factor by microRNAs

open access: yes, 2010
Post-transcriptional gene regulation is a very powerful and evolutionary conserved mechanism which allows cells to finely modulate gene expression by acting at the level of their mRNAs.
Calissano, M.
core  

Homogenous Cell Transplantation Trials in Parkinson's Disease: A Systematic Review and Meta‐Analysis

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background The transplantation of homogenous cells has emerged as an investigational strategy for Parkinson's disease (PD), offering an alternative to symptomatic treatment. Objective We performed a systematic review and meta‐analysis to assess its clinical efficacy and safety.
Nolan Reinisch   +4 more
wiley   +1 more source

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