Results 131 to 140 of about 4,628,424 (310)
Triggered Calcium Lightning Programs Cochlear Development
Exploration, EarlyView.Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma +13 more
wiley +1 more source
Hypoxia-ischemia and retinal ganglion cell damage
, 2008 Charanjit Kaur1, Wallace S Foulds2, Eng-Ang Ling11Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; 2Singapore Eye Research Institute, SingaporeAbstract: Retinal hypoxia is the potentially blinding ...
Eng-Ang Ling +2 more
core
, 2011 Objective: To evaluate the neuroprotective effect of short-term hyperglycemia on the retinal ganglion cell body and axon in a rat model of experimental glaucoma.
Casson, Robert J. +8 more
core +1 more source
Exploration, EarlyView.This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi +5 more
wiley +1 more source
Bevacizumab Is Not Toxic to Retinal Ganglion Cells after Repeated Intravitreal Injection
, 2011 Purpose: The cytotoxicity of single and repeated administration of bevacizumab to retinal ganglion cells was studied in vivo and in vitro. Methods: Rats received single or repeated injections of 125 mu g of bevacizumab into the vitreous cavity of the ...
CHENG, CHENG-KUO;PENG, PAI-HUEI;TIEN, LU-TAI;CHEN, CHAU-FONG;LEE, YIH-JING +1 more
core +1 more source
Bio‐inspired vision: From principle, material architectures to system‐level integration
FlexMat, EarlyView.This review introduces the development and mechanism of electronic and ionic bio‐inspired vision devices respectively. Then, it explores the impact of structure on bio‐inspired visual performance from the scale of intrinsic materials and device. Finally, it concludes that only by combining advanced software and technology can more complex vision ...
Zewan Lin +4 more
wiley +1 more source
Optic Nerve Thickness Assessed by Ocular Ultrasonography in Obstructive Sleep Apnea
Journal of Ultrasound in Medicine, EarlyView.Objectives Obstructive sleep apnea (OSA) has been associated with various ocular complications, yet ultrasonographic evaluation of optic nerve thickness and its relationship with nocturnal hypoxemia remains poorly understood. This study aimed to evaluate optic nerve thickness and globe dimensions using ocular ultrasonography in patients with different ...
Buğra Kerget +4 more
wiley +1 more source
Retinal Ganglion Cell Loss in Diabetes Associated with Elevated Homocysteine
, 2009 A number of studies have suggested that homocysteine may be a contributing factor to development of retinopathy in diabetic patients based on observed correlations between elevated homocysteine levels and the presence of retinopathy.
Kenneth S. Shindler
core
Orbital Lymphatic Malformations Are Associated With Intracranial Vascular Anomalies
The Laryngoscope, EarlyView.In this retrospective series, all seven patients with orbital lymphatic malformations had intracranial vascular anomalies consistent with cerebrofacial venous metameric syndrome and hotspot PIK3CA variants identified through tissue‐based sequencing. Five patients treated with alpelisib experienced symptom improvement within 6 months.
Kelsey A. Loy +11 more
wiley +1 more source