Abstract Objective The aim of this study was to retrospectively evaluate vision outcomes of dogs with primary angle closure glaucoma (PACG) that underwent Ahmed valve gonioimplantation (AVG) followed by lensectomy and endolaser cyclophotocoagulation (ECP) with or without bleb resection after AVG failure.
Bactelius Turicea +3 more
wiley +1 more source
Pharmacological restoration of impaired autophagy in retinal ganglion cells prevents abnormal mitochondrial accumulation and glaucomatous neurodegeneration. [PDF]
Maddineni P +9 more
europepmc +1 more source
Abstract Objective To report preliminary results of MP‐TSCP in canine patients with glaucoma while evaluating sweep velocity, treatment efficacy, and safety utilizing standardized surgical parameters. Animal studied Client‐owned dogs that underwent MP‐TSCP at a veterinary referral hospital. Procedure Medical records of 19 eyes (14 dogs) treated with MP‐
Valeria Benitez‐Vera +2 more
wiley +1 more source
Nox3 expression and function in retinal ganglion cells and Amacrine cells. [PDF]
Ueyama T +10 more
europepmc +1 more source
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Differentiation timing-dependent axon targeting and subtype specification in retinal ganglion cells. [PDF]
Iwai L, Hirata T.
europepmc +1 more source
TMEM16A channel signalling microdomains in the regulation of vascular function
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley +1 more source
Energetic diversity in retinal ganglion cells is modulated by neuronal activity and correlates with resilience to degeneration. [PDF]
Wang Z +6 more
europepmc +1 more source
Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow
Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley +1 more source
Microtubule dynamics in adult retinal ganglion cells and dorsal root ganglion neurons. [PDF]
Vecino E +8 more
europepmc +1 more source

