Results 141 to 150 of about 15,573 (263)

A comparative study of the potential for human retinal pigment epithelium utilising an embryonic chick model of the phenomenon

open access: yes, 2014
The retinal pigment epithelial (RPE) cells of several species, including: chicken, rat, mouse and newt, have been observed to undergo a phenomenon known as transdifferentiation.
Smart, MJK
core  

Minocycline and bone marrow–derived mononuclear cells as potential therapeutics for hereditary retinal degenerations

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To assess in Royal College of Surgeons (RCS) rats if the combination of two previously documented neuroprotective strategies: minocycline administration and bone marrow–derived mononuclear cells (BM‐MNCs) intravitreal transplantation, offers enhanced neuroprotection compared with each treatment alone.
Alba Videla‐Ristol   +6 more
wiley   +1 more source

Labelling and Longitudinal In Vivo Imaging of Retinal Ganglion Cells

open access: yes, 2017
The ability to detect and quantify retinal ganglion cell (RGC) loss is important for the diagnosis and monitoring of optic neuropathies, such as glaucoma.
Smith, Corey A
core  

Prenatal and childhood exposure to smoking and retinal nerve fibre layer thickness: A meta‐analysis of three independent birth cohorts

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To examine retinal nerve fibre layer (RNFL) characteristics in relation to prenatal and postnatal smoking exposure in three independent birth cohorts: two Danish and one Australian cohort. Methods A combined meta‐analysis of peripapillary retinal nerve fibre thickness in the Copenhagen Prospective Studies on Asthma in Childhood 2000 ...
Linna Zhu   +8 more
wiley   +1 more source

p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma model

open access: yesNeural Regeneration Research
Glutamate excitotoxicity has been shown to play an important role in glaucoma, and glutamate can induce ferroptosis. The p38 mitogen-activated protein kinase (MAPK) pathway inhibitor SB202190 has a potential ability to suppress ferroptosis, and its ...
Lemeng Feng   +7 more
doaj   +1 more source

Association between metabolic syndrome, macular structures and retinal vascular calibres in the Northern Finland Birth Cohort Eye Study

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose We aimed to evaluate the association of metabolic syndrome (MetS) with macular thickness and retinal vascular calibres in the population‐based cohort (Northern Finland Birth Cohort). Methods The population of 2242 individuals was divided into MetS (n = 344) and control groups (n = 1898).
Jenni M. Huru   +4 more
wiley   +1 more source

A Neurotrophic Model of the Development of the Retinogeniculocortical Pathway Induced by Spontaneous Retinal Waves

open access: yes, 1999
The development of the retinogeniculate pathway or the geniculocortical pathway, or both, occurs either before birth or before eye opening in many species.
Shadbolt, N. R   +3 more
core   +1 more source

Interpreting the structure–function relationship in high myopia‐associated glaucoma: A review

open access: yesActa Ophthalmologica, EarlyView.
Abstract Visual field (VF) interpretation in high myopia‐associated glaucoma (HMG) is challenging due to frequent structure–function discordance and coexisting myopia‐related changes. These changes may reduce the reliability of conventional structure–function mapping and increase the risk of misclassifying non‐glaucomatous VF abnormalities as ...
Ruby S. Chan   +6 more
wiley   +1 more source

Hormonal replacement therapy in postmenopausal women ≥50 years is associated with the incidence of glaucoma: Evidence from 6576 females in Finland

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Hormonal replacement therapy (HRT) in postmenopausal women appears to affect glaucoma risk, but findings are inconsistent. We aimed to explore whether the use of postmenopausal HRT plays a role in glaucoma development in Finland. Methods The main outcome variable was glaucoma incidence measured by initiation of special reimbursement ...
Sirpa Loukovaara, Jari Haukka
wiley   +1 more source

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