Amacrine cell inputs to OFF midget ganglion cells in macaque retina
Abstract figure legend The goal of this study was to explain the findings from physiological studies that OFF midget ganglion cells had larger receptive field centers than expected from their dendritic field diameters. First, we confirmed that OFF mRGCs (OFF MGC) receive input from diffuse bipolar cells (DB) as well as OFF midget bipolar cells (FMB ...
David W. Marshak +8 more
wiley +1 more source
Autophagy Impairment in Retinal Ganglion Cells Following Hypoglycemia in Mice. [PDF]
Fresia D +4 more
europepmc +1 more source
The what, which, when, why and who of Off responses in the auditory system
Abstract figure legend In this article, we will first review ‘What’ different mechanisms are involved in the generation of Off responses at the sub‐cortical and cortical level of the auditory system. Then, we evaluate ‘Which’ stimulus properties elicit Off responses at the different levels of the auditory system.
Jean‐Marc Edeline, Robert C. Liu
wiley +1 more source
Blocking apoptosis promotes survival and alters developmental dynamics of human retinal ganglion cells in retinal organoids. [PDF]
Zhang JS +7 more
europepmc +1 more source
Population-scale analysis of frequency-dependent calcium dynamics in retinal ganglion cells under electric field stimulation. [PDF]
Sharafi O +7 more
europepmc +1 more source
Müller Glia–Vasculature Interactions in the Developing Retina
Retinal vascular layers form normally despite loss of cholinergic retinal waves. Müller glial processes contact endothelial tip cells early and form Aquaporin‐4‐enriched endfeet. Glial endfoot calcium signals are compartmentalized and occur largely independently of neural activity. ABSTRACT Coordinated signaling among neurons, glia, and the vasculature
Samira Monshietehadi +6 more
wiley +1 more source
The Form and Function of Retinal Ganglion Cells in Diabetes. [PDF]
Barber AJ.
europepmc +1 more source
New perspectives on VEGF signalling in Alzheimer's disease
Emery et al. bring together findings from recent multi‐omic studies, including single‐cell mRNA analysis of human post‐mortem brain tissue, and proteomic analysis of matched CSF and blood samples in large clinical studies. The authors present evidence of the involvement of altered VEGF signalling in vascular and immune dysfunction and neurodegeneration
Cherelle E. G. Emery +2 more
wiley +1 more source
PRDM16 protects retinal ganglion cells from ischemia-reperfusion Injury by regulating the RPL5/p53 axis. [PDF]
Feng Y +12 more
europepmc +1 more source
Opticus atrophy—Genetic testing with WES/WGS in 62 patients with optic atrophy provided a genetic diagnosis in 21 patients (33.9%). 42.9% of these involved non‐OPA1 genes, including WFS1, ACO2, NR2F1, UCHL1, CACNA1F, and COQ2, where the genetic diagnosis prompted additional clinical evaluation, surveillance, or therapeutic intervention.
Katrine M. Johannesen +9 more
wiley +1 more source

