Results 171 to 180 of about 60,940 (264)

The 9th International RASopathies Symposium

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1934-1941, August 2026.
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel, Lisa Schoyer, Beth Stronach, Raya Bogdanova, Anton M. Bennett, Jaishri Blakeley, Miriam Bornhorst, Tammy Bowers, Saskia M. Brachmann, Emma Burkitt‐Wright, Kathryn Chatfield, Alessandro De Luca, Khalil El‐Chammas, Abdul Elkadri, John E. Fortunato, Bruce D. Gelb, Anne Goriely, Karen Gripp, Kassidy Grover, Lindsay Homan, Kenneth A. Kern, Maija Kiuru, Charles (Chuck) Lawson, Yong‐Seok Lee, Frank McCormick, Gina Ney, Cristina Nuevo‐Tapioles, Sara Pardej, Elizabeth I. Pierpont, Julia Plank, Nancy Ratner, Katherine A. Rauen, J. Elliott Robinson, Les Rogers, Sarah E. Sheppard, Keir Shiels, David Stevenson, Dagmar Tiemens, Matthew Traylor, K. Nicole Weaver, Marielle Yohe, Tamar Green   +41 more
wiley   +1 more source

HDAC4 Promotes Neuroprotection of Retinal Ganglion Cells After Optic Nerve Injury. [PDF]

Invest Ophthalmol Vis Sci
Zhu Y, Yan W, Bian M, Xia X, Nahmou M, Nair RV, Li J, Li X, Thakur HS, Sun CB, Russano K, Luo Z, Huie EL, Chang HV, Ochoa JR, Goldberg JL, Kapiloff MS.   +16 more
europepmc   +1 more source

Early identification of vascular cognitive impairment from a multimodal perspective: a combined diagnosis from targeted cognitive assessments, imaging biomarkers, and molecular fluid biomarkers to ecological behavioral characteristics

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract Vascular cognitive impairment (VCI), the second leading cause of dementia, is characterized by heterogeneous pathophysiology and a potentially reversible early phase, underscoring the need for timely identification. This review synthesizes advances across four complementary domains – targeted cognitive assessments, imaging biomarkers ...
Wenqi Song, Xiaoqun Liu, Tianrui Yu, Yuanyuan Xiang, Peijie Fu, Moxin Wu, Xiaoping Yin, Xiaorong Zhang, Zhiying Chen   +8 more
wiley   +1 more source

A TRIP‐nano killer silencing the pain pacemakers

The Journal of Physiology, EarlyView.
Elisabetta Cerbai
wiley   +1 more source

Retinal Layer Thickness for Risk Stratification of Progression Independent of Relapse Activity in Relapsing‐Remitting Multiple Sclerosis

Brain and Behavior, Volume 16, Issue 8, August 2026.
This study assessed the prognostic value of optical coherence tomography‐derived thicknesses of the peripapillary retinal nerve fiber and ganglion cell‐inner plexiform layer for identifying people with relapsing‐remitting multiple sclerosis at risk of progression independent of relapse activity (PIRA) from two German centers.
Andre Braginets, Frederike Cosima Oertel, Eva‐Maria Strauß, Carla Leutloff, Tanja Schmitz‐Hübsch, Friedemann Paul, Susanna Asseyer, Rebecca Wicklein, Bernhard Hemmer, Klemens Ruprecht, Hanna Gwendolyn Zimmermann, Benjamin Knier, Ting‐Yi Lin   +12 more
wiley   +1 more source

Bipolar cell networks underlying steady-state intensity encoding in intrinsically photosensitive retinal ganglion cells. [PDF]

iScience
Sabbah S, Papendorp C, Behrendt I, Rasras H, Cann J, Leyrer ML, Koplas E, Beltoja M, Etebari C, Gunesch AN, Carrete L, Kim MT, Manoff G, Bhatia-Lin A, Zhao T, Dowling H, Briggman KL, Berson DM.   +17 more
europepmc   +1 more source

Comparative Neuroanatomy of Hydrothermal Vent Shrimps: Ecological Differentiation Among Four Alvinocaridid Species

Journal of Comparative Neurology, Volume 534, Issue 8, August 2026.
Hydrothermal vent shrimps share a conserved brain architecture with enlarged mushroom bodies and terminal medullae, shaped by similar environmental pressures. Despite this similarity, some anatomical features near the brain vary between species, suggesting that some ecological factors, such as microhabitat and trophic strategies, also influence nervous
Adrien Mathou, Julia Machon, Rebecca Meth, Magali Zbinden, Juliette Ravaux, Steffen Harzsch   +5 more
wiley   +1 more source

A complete spatial map of mouse retinal ganglion cells reveals density and gene expression specializations. [PDF]

Proc Natl Acad Sci U S A
Budoff SA, Poleg-Polsky A.
europepmc   +1 more source

Brain‐Wide Mapping and Synaptic Localization of C1QL3 Using a Novel Epitope‐Tagged Knock‐In Mouse

Journal of Comparative Neurology, Volume 534, Issue 8, August 2026.
C1QL3 is a secreted adhesion molecule that acts as a key regulator of synaptic structure and function. We generated and validated a novel epitope‐tagged knock‐in mouse line (C1ql32HA) in which two hemagglutinin (HA) epitopes were inserted near the N‐terminus of the endogenous C1QL3 protein.
William P. Armstrong IV, James M. Salvatore, Matthew J. Sticco, Keaven Caro, J. Wesley Maddox, Angie Huang, Brenna C. McAllister, Christopher B. O'Connell, Siu‐Pok Yee, Amy Lee, Susanne Ressl, David C. Martinelli, Alexander C. Jackson   +12 more
wiley   +1 more source

OPTN protects retinal ganglion cells and ameliorates neuroinflammation in optic neuropathies. [PDF]

Commun Biol
Wang Q, Wang Y, Jiang YDD, Donahue R, Cao G, Yan W, Guo H, Li Z, Liang J, Hao J, Lu Y, Bei F, Wang Q, Tian F.   +13 more
europepmc   +1 more source