Results 101 to 110 of about 286,988 (401)

How lateral inhibition and fast retinogeniculo-cortical oscillations create vision: A new hypothesis [PDF]

open access: yes, 2016
The role of the physiological processes involved in human vision escapes clarification in current literature. Many unanswered questions about vision include: 1) whether there is more to lateral inhibition than previously proposed, 2) the role ...
Barnes, Vernon A.   +3 more
core   +1 more source

A Facile Strategy to Restore the Optic Nerve Functionality Using an Injectable Conducting Hydrogel

open access: yesAdvanced Science, EarlyView.
An injectable conductive polymer hydrogel from poly (3,4‐ethylenedioxythiophene) (PEDOT) is developed to facilitate the recovery of electrophysiological function in injured optic nerve. The hydrogel can be injected directly at the injury site and spontaneously gel in place.
Changchun Yu   +12 more
wiley   +1 more source

Atoh7-independent specification of retinal ganglion cell identity

open access: yesScience Advances, 2020
Atoh7 promotes retinal ganglion survival and is not required for specification of most retinal ganglion cells. Retinal ganglion cells (RGCs) relay visual information from the eye to the brain.
Justin Brodie-Kommit   +17 more
semanticscholar   +1 more source

Improving Adult Vision Through Pathway‐Specific Training in Augmented Reality

open access: yesAdvanced Science, EarlyView.
Traditional perceptual training approaches are limited by stimulus specificity, treatment efficacy, and patient compliance. A novel altered reality (AR) method is developed to enhance pathway‐specific functions in human adults while performing everyday activities.
Yige Gao   +4 more
wiley   +1 more source

Combined suppression of CASP2 and CASP6 protects retinal ganglion cells from apoptosis and promotes axon regeneration through CNTF-mediated JAK/STAT signalling.

open access: yesBrain : a journal of neurology, 2014
We have previously shown that crushing the optic nerve induces death of retinal ganglion cells by apoptosis, but suppression of CASP2, which is predominantly activated in retinal ganglion cells, using a stably modified short interfering RNA CASP2 ...
V. Vigneswara   +5 more
semanticscholar   +1 more source

A Unified Model of Spatiotemporal Processing in the Retina [PDF]

open access: yes, 1992
A computational model of visual processing in the vertebrate retina provides a unified explanation of a range of data previously treated by disparate models.
Gaudiano, Paolo
core   +1 more source

Magnetic‐Guided Delivery of Antisense Oligonucleotides for Targeted Transduction in Multiple Retinal Explant and Organoid Models

open access: yesAdvanced Science, EarlyView.
Magnetic field‐guided MNP@ATR‐ASO nanocomplexes facilitate the targeted delivery of ASOs to ganglion cells or photoreceptors within retinal explants, thereby enhancing the efficacy of ASOs in correcting pre‐mRNA splicing abnormalities. Furthermore, the nanocomplexes improve ASO penetration and delivery in human retinal and inner ear organoid models ...
Xiuhong Ye   +13 more
wiley   +1 more source

Gαq signalling from endosomes: A new conundrum

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract G‐protein‐coupled receptors (GPCRs) constitute the largest family of membrane receptors, and are involved in the transmission of a variety of extracellular stimuli such as hormones, neurotransmitters, light and odorants into intracellular responses.
Carole Daly, Bianca Plouffe
wiley   +1 more source

Nicotinamide and WLDS Act Together to Prevent Neurodegeneration in Glaucoma

open access: yesFrontiers in Neuroscience, 2017
Glaucoma is a complex neurodegenerative disease characterized by progressive visual dysfunction leading to vision loss. Retinal ganglion cells are the primary affected neuronal population, with a critical insult damaging their axons in the optic nerve ...
Simon W. M. John   +6 more
doaj   +1 more source

Methods of Retinal Ganglion Cell Differentiation From Pluripotent Stem Cells.

open access: yesTranslational Vision Science & Technology, 2014
Glaucoma, the worldwide leading cause of irreversible blindness, is characterized by progressive degeneration of the optic nerve and loss of retinal ganglion cells.
K. P. Gill   +4 more
semanticscholar   +1 more source

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