Results 111 to 120 of about 286,988 (401)
Molecular Phenotyping of Retinal Ganglion Cells [PDF]
The Journal of Neuroscience, 2002 Classifying all of the ganglion cells in the mammalian retina has long been a goal of anatomists, physiologists, and cell biologists. The rabbit retinal ganglion cell layer was phenotyped using intrinsic small molecule signals (aspartate, glutamate, glycine, glutamine, GABA, and taurine) and glutamate receptor-gated 1-amino-4-guanidobutane excitation ...
Bryan W. Jones, Robert E. Marc
openaire +2 more sources
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Advanced Science, EarlyView.Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang +4 more
wiley +1 more source
Cell based therapies for glaucoma
Advances in Clinical Neuroscience & Rehabilitation, 2016 Stem cells could be useful in the treatment of glaucoma by improving aqueous outflow to lower eye pressure, by protecting retinal ganglion cells directly against glaucoma damage or by facilitating optic nerve regeneration.
Craig Pearson, Keith Martin
doaj +1 more source
Attenuation of the Ganglion Cell Layer in a Premature Infant Revealed with Handheld Spectral Domain Optical Coherence Tomography [PDF]
, 2016 Purpose: To report on subclinical retinal abnormalities shown through handheld spectral domain optical coherence tomography on a premature infant. Methods: Case report.
Carroll, Joseph +3 more
core +2 more sources
Advanced Electronic Materials, EarlyView.An optoelectronic memristor based on an ultrathin periodic heterostructure is proposed. The unique structure enables the integration of multiple functionalities, including those of a photodetector, electric synapse, and optical synapse. This work provides a framework to design ultrathin, multifunctional, and energy‐efficient neuromorphic chips for ...
Lilan Zou +4 more
wiley +1 more source
Acta Neuropathologica Communications, 2023 Retinal ganglion cells are highly metabolically active requiring strictly regulated metabolism and functional mitochondria to keep ATP levels in physiological range.
Alessio Canovai +7 more
doaj +1 more source
Investigative Ophthalmology and Visual Science, 2013 PURPOSE To investigate the potential therapeutic benefit of intravitreally implanted dental pulp stem cells (DPSCs) on axotomized adult rat retinal ganglion cells (RGCs) using in vitro and in vivo neural injury models.
B. Mead +4 more
semanticscholar +1 more source
Retinal ganglion cells: dying to survive
The International Journal of Developmental Biology, 2006 This review examines the maturation of the retinal ganglion cell (RGC) population within the nascent retina. Apoptosis, a form of programmed cell death prevalent throughout the developing central nervous system (CNS), is evident in the growth of RGCs within the ganglion cell layer.
Marc B Guerin +3 more
openaire +4 more sources
Animal Models and Experimental Medicine, EarlyView.The present study investigates the role of the NLRP3 inflammasome in the chronicity of ocular inflammation in uveitis using the experimental autoimmune uveitis (EAU) model. Whole eyes collected from EAU mice, 12 weeks post induction, were sectioned and subjected to immunohistochemistry. The confocal images from these sections were then assessed for the
Avik Shome +3 more
wiley +1 more source
Marine Drugs, 2013 Diabetic retinopathy is a common diabetic eye disease caused by changes in retinal ganglion cells (RGCs). It is an ocular manifestation of systemic disease, which affects up to 80% of all patients who have had diabetes for 10 years or more.
Ling-yan Dong +3 more
semanticscholar +1 more source