Results 151 to 160 of about 238,606 (323)

Hcfc1 and Ogt Mediate Zebrafish CNS Regeneration Through Hippo/Yap Signalling

Cell Proliferation, EarlyView.
This work identifies Hcfc1 and Ogt as key regulators of zebrafish CNS regeneration through modulation of Hippo/Yap signalling. Loss of Hcfc1 or Ogt activity inhibition impairs regeneration, which is restored by Yap overexpression, revealing a new regulatory axis that enhances CNS regenerative capacity.
Priyanka P. Srivastava, Sidharth Bhasin, Poonam Sharma, Omkar Mahadeo Desai, Kshitiz Yadav, Ayushma, Rohan Chakraborty, Suhel Parvez, Rajesh Ramachandran, Shilpi Minocha   +9 more
wiley   +1 more source

Stage‐Associated Microglial Subpopulations and Dynamics in Vascular Pathogenesis of Oxygen‐Induced Retinopathy

Cell Proliferation, EarlyView.
In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma, Ziye Chen, Baoyi Liu, Wen Ding, Runping Duan, Kangjie Kong, Zhuojun Xu, Jizhu Li, Jiali Ru, Dianlei Guo, Xiaoyue Wei, Yaping Liu, Zhuangling Lin, Yang Meng, Yuan Liu, Lan Jiang, Zitong Chen, Rebiya Tuxun, Chinling Tsai, Chunqiao Liu, Tao Li   +20 more
wiley   +1 more source

The technical and practical implementation of fundus photography in equids

Equine Veterinary Education, EarlyView.
Summary Background Fundus photography is an important diagnostic tool in human and veterinary medicine. Advances in research are increasing its accessibility in human medicine. However, there is a lack of studies on modern fundus photography in animals, particularly in horses. Objectives To assess the use of a portable fundus camera developed for human
I. Vierling, B. Wollanke, V. Franzen
wiley   +1 more source

Transcriptional regulation of human NMNAT2: insights from 3D genome sequencing and bioinformatics

The FEBS Journal, EarlyView.
NMNAT2 is a valuable drug target, as low levels increase the risk of neurodegeneration. We employed 4C‐seq to identify NMNAT2 regulatory regions in the human genome, revealing distinct interactomes of the NMNAT2 promoter in undifferentiated and neuron‐like SH‐SY5Y cells. Additionally, we uncovered NMNAT2‐associated genes and transcription factors. This
Yu Chen Chang, Sen Yang, Minyoung Cho, Kwangsik Nho, José‐Manuel Baizabal, Hui‐Chen Lu   +5 more
wiley   +1 more source

Diversity of intrinsically photosensitive retinal ganglion cells: circuits and functions

Cellular and Molecular Life Sciences, 2020
Marcos L. Aranda, Tiffany M. Schmidt
semanticscholar   +1 more source

Mapping Escolar (Lepidocybium flavobrunneum) in Motion: Oceanographic Forces Shaping Its Habitat in the Southwestern South Atlantic, With Insights From Fishers' Perceptions

Fisheries Oceanography, EarlyView.
ABSTRACT Lepidocybium flavobrunneum [Smith, 1843], commonly known as escolar, is a large pelagic species, important for global and local fisheries, particularly in the southwestern South Atlantic Ocean (SWAO), where it constitutes a significant portion of the catch.
Lucas Rodrigues, Maria Grazia Pennino, Paul Gerhard Kinas, David Conesa, Alba Fuster‐Alonso, Andrés Domingo, Rodrigo Forselledo, Federico Mas, Bruno Mourato, Rodrigo Sant'Ana, Vinni Santos Thykjaer, Raquel Virginia Marquez Marquez, Abner Ventura Alves, Mariano Cabanillas‐Torpoco, Rafael Schroeder, Luis Gustavo Cardoso   +15 more
wiley   +1 more source

Melanopsin-Containing Retinal Ganglion Cells: Architecture, Projections, and Intrinsic Photosensitivity

Science, 2002
S. Hattar, H. Liao, M. Takao, D. Berson, K.-W. Yau, K.-W. Yau   +5 more
semanticscholar   +1 more source

The hidden science of haptics: A pedagogical review of tactile evaluation in cosmetics

International Journal of Cosmetic Science, EarlyView.
This review explores the physiological basis of tactile perception and critically examines classical and emerging sensory methods used in cosmetics, advocating for broader methodological integration and recognition of sensory analysis in the field. Abstract Sensory analysis is a cornerstone of cosmetic development, yet remains underrepresented in peer ...
Morgane Postec, Daria Terescenco, Ecaterina Gore   +2 more
wiley   +1 more source

Increased C‐reactive protein is associated with corneal nerve loss and painful neuropathic symptoms in Type 2 diabetes mellitus

Journal of Diabetes Investigation, EarlyView.
Higher circulating C‐reactive protein, a marker of systemic inflammation, is associated with reduced corneal small nerve fiber density in individuals with Type 2 diabetes mellitus. Among participants with diabetic peripheral neuropathy, CRP levels are highest in those reporting positive neuropathic symptoms such as burning, painful cold, or electric ...
Georgios Ponirakis, Ibrahim Al‐Janahi, Einas Elgassim, Ioannis N. Petropoulos, Hoda Gad, Adnan Khan, Hadeel B. Zaghloul, Hamda Ali, Mashhood A. Siddique, Sidra Abdulshakoor, Jenneth M. Concepcion, Sara H. Khalfalla, Iynas S. A. Elamin, Abeer T. H. AlZawqari, Tania Bibi, Marwa A. El Deeb, Lina H. M. Ahmed, Youssra Dakroury, Abeer M. M. El Shewehy, Iuliia Salivon, Mohammad Qasim Minhas, Yara Ismail, Mahmoud A. Zirie, Yousuf Al‐Ansari, Mariam A. O. Al‐Malaheem, Dorothy J. Quadros, Stephen L. Atkin, Rayaz A. Malik   +27 more
wiley   +1 more source

The contrast sensitivity of retinal ganglion cells of the cat

Journal of Physiology, 1966
C. Enroth-Cugell, J. Robson
semanticscholar   +1 more source