Results 61 to 70 of about 286,988 (401)
Valproate reduces retinal ganglion cell apoptosis in rats after optic nerve crush
Neural Regeneration Research, 2023 The retinal ganglion cells of the optic nerve have a limited capacity for self-repair after injury. Valproate is a histone deacetylase inhibitor and multitarget drug, which has been demonstrated to protect retinal neurons.
Feng Pan +5 more
doaj +1 more source
Do retinal ganglion cells project natural scenes to their principal subspace and whiten them? [PDF]
, 2016 Several theories of early sensory processing suggest that it whitens sensory stimuli. Here, we test three key predictions of the whitening theory using recordings from 152 ganglion cells in salamander retina responding to natural movies. We confirm the previous finding that firing rates of ganglion cells are less correlated compared to natural scenes ...
arxiv +1 more source
Retinal adaptation and invariance to changes in higher-order stimulus statistics [PDF]
PLOS One 9 (2014): e85841, 2012 Adaptation in the retina is thought to optimize the encoding of natural light signals into sequences of spikes sent to the brain. However, adaptation also entails computational costs: adaptive code is intrinsically ambiguous, because output symbols cannot be trivially mapped back to the stimuli without the knowledge of the adaptive state of the ...
arxiv +1 more source
Mood, the Circadian System, and Melanopsin Retinal Ganglion Cells.
Annual Review of Neuroscience, 2017 The discovery of a third type of photoreceptors in the mammalian retina, intrinsically photosensitive retinal ganglion cells (ipRGCs), has had a revolutionary impact on chronobiology.
Lorenzo Lazzerini Ospri +2 more
semanticscholar +1 more source
Targeting retinal ganglion cell recovery [PDF]
Eye, 2017 Accumulating evidence from experimental and clinical studies suggest that retinal ganglion cells at least in the earlier stages of glaucoma have the capacity to recover function following periods of functional loss. The capacity for recovery may be negatively impacted by advancing age but can be boosted by interventions such as diet restriction and ...
Steven Petrou +6 more
openaire +3 more sources
Single-cell RNA sequencing analysis of the retina under acute high intraocular pressure
Neural Regeneration ResearchHigh intraocular pressure causes retinal ganglion cell injury in primary and secondary glaucoma diseases, yet the molecular landscape characteristics of retinal cells under high intraocular pressure remain unknown. Rat models of acute hypertension ocular
Shaojun Wang +7 more
doaj +1 more source
Neuroprotection of Retinal Ganglion Cells [PDF]
, 2010 Therapeutic efforts for treatment of glaucoma have focused on reduction of intraocular pressure as the main objective. In clinical practice, intraocular pressure (IOP) control has been expected to slow or arrest the glaucoma progression. However, clinicians have been confronted with significant glaucoma progression even when achieving control of ...
Peter A. Netland +2 more
openaire +2 more sources
Neural Regeneration Research, 2023 Successful establishment of reconnection between retinal ganglion cells and retinorecipient regions in the brain is critical to optic nerve regeneration.
Zong-Yi Zhan +11 more
doaj +1 more source
Retinal Ganglion Cells and Circadian Rhythms in Alzheimer’s Disease, Parkinson’s Disease, and Beyond
Frontiers in Neurology, 2017 There is increasing awareness on the role played by circadian rhythm abnormalities in neurodegenerative disorders such as Alzheimer’s disease (AD) and Parkinson’s disease (PD).
C. La Morgia +3 more
semanticscholar +1 more source
Dendritic and axonal targeting patterns of a genetically-specified class of retinal ganglion cells that participate in image-forming circuits. [PDF]
, 2014 BackgroundThere are numerous functional types of retinal ganglion cells (RGCs), each participating in circuits that encode a specific aspect of the visual scene.
Feldheim, David A +6 more
core +2 more sources