Results 1 to 10 of about 41,612 (247)

CM082 suppresses hypoxia-induced retinal neovascularization in larval zebrafish [PDF]

open access: yesFrontiers in Pharmacology
Retinal neovascularization is a common feature of several ocular neovascular diseases, which are the leading cause of blindness in the world. Current treatments are administered through invasive intravitreal injections, leading to poor patient compliance,
Jun-long Zhang   +4 more
doaj   +2 more sources

Peripapillary retinal neovascularization and vitreous hemorrhage secondary to peripapillary pachychoroid syndrome [PDF]

open access: yesAmerican Journal of Ophthalmology Case Reports
Purpose: To report a case of peripapillary pachychoroid syndrome (PPS) complicated with peripapillary retinal neovascularization causing vitreous hemorrhage.
Imène Zhioua Braham   +4 more
doaj   +2 more sources

TAK1 blockade as a therapy for retinal neovascularization

open access: yesPharmacological Research, 2023
Retinal neovascularization, or pathological angiogenesis in the retina, is a leading cause of blindness in developed countries. Transforming growth factor-β-activated kinase 1 (TAK1) is a mitogen-activated protein kinase kinase kinase (MAPKKK) activated
Jinying Chen   +2 more
exaly   +1 more source

FGF21 Administration Suppresses Retinal and Choroidal Neovascularization in Mice

open access: yesCell Reports, 2017
Pathological neovascularization, a leading cause of blindness, is seen in retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration.
Zhongjie Fu   +12 more
doaj   +2 more sources

Intravitreal Aflibercept as a Rescue Therapy for Retinal Neovascularization and Macular Edema due to Eales Disease

open access: yesCase Reports in Ophthalmological Medicine, 2021
We report the rescue effect of intravitreal aflibercept injections on retinal neovascularization and macular edema due to Eales disease. Case 1 was a 36-year-old female. Intravitreal aflibercept was administered as rescue therapy after persistent retinal
Ning-Yi Hsia   +6 more
doaj   +1 more source

The progress of prophylactic treatment in retinopathy of prematurity [PDF]

open access: yesInternational Journal of Ophthalmology, 2018
Retinopathy of prematurity (ROP) is a retinal vascular disorder frequently found in premature infants. Different therapeutic strategies have been developed to treat ROP.
Hong-Bing Zhang   +3 more
doaj   +1 more source

Peripheral retinal neovascularization in a patient with obstructive sleep apnea

open access: yesAmerican Journal of Ophthalmology Case Reports, 2022
Purpose: To describe a case of peripheral retinal neovascularization and its possible etiological connection to comorbid obstructive sleep apnea. Observations: In this case report we describe a diabetic patient with obstructive sleep apnea who presented ...
Ravin Sajnani   +4 more
doaj   +1 more source

An Endostatin-lentivirus (ES-LV)-EPC gene therapy agent for suppression of neovascularization in oxygen-induced retinopathy rat model

open access: yesBMC Molecular and Cell Biology, 2020
Background Transplantation of gene transfected endothelial progenitor cells (EPCs) has provided novel methods for tumor neovascularization therapy but not for ocular disease therapy.
Jing Ai   +4 more
doaj   +1 more source

YY1 lactylation in microglia promotes angiogenesis through transcription activation-mediated upregulation of FGF2

open access: yesGenome Biology, 2023
Background Ocular neovascularization is a leading cause of blindness. Retinal microglia have been implicated in hypoxia-induced angiogenesis and vasculopathy, but the underlying mechanisms are not entirely clear.
Xiaotang Wang   +10 more
doaj   +1 more source

Fluorescein angiography compared to three-dimensional measurements by the retinal thickness analyzer in classic choroidal neovascularization [PDF]

open access: yes, 2007
Purpose: To compare and correlate imaging of classic subfoveal choroidal neovascularization (CNV) with noninvasive 3-dimensional imaging by the retinal thickness analyzer (RTA) to conventional fluorescein angiography (FA).
Strauss, R. W.   +3 more
core   +1 more source

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