Results 1 to 10 of about 385,405 (300)
Ferrochelatase regulates retinal neovascularization [PDF]
The FASEB Journal, 2020 Ferrochelatase (FECH) is the terminal enzyme in heme biosynthesis. We previously showed that FECH is required for endothelial cell growth in vitro and choroidal neovascularization in vivo.
Sheik Pran Babu Sardar Pasha +2 more
semanticscholar +5 more sources
IL-17A Enhances Retinal Neovascularization. [PDF]
Int J Mol Sci, 2023 Retinal neovascularization occurs in proliferative diabetic retinopathy, neovascular glaucoma, and age-related macular degeneration. This type of retinal pathology normally occurs in the later stages of these ocular diseases and is a prevalent cause of ...
Taylor BE +7 more
europepmc +4 more sources
eLife, 2019 Constitutive TGFβ signaling is important in maintaining retinal neurons and blood vessels and is a factor contributing to the risk for age-related macular degeneration (AMD), a retinal disease involving neurodegeneration and microglial activation.
Wenxin Ma +6 more
doaj +3 more sources
MicroRNA-18a-5p Administration Suppresses Retinal Neovascularization by Targeting FGF1 and HIF1A
Frontiers in Pharmacology, 2020 Pathologic ocular neovascularization commonly results in visual impairment or even blindness in numerous fundus diseases, including proliferative diabetic retinopathy (PDR), retinopathy of prematurity (ROP), and age-related macular degeneration (AMD ...
Ji-Tian Guan +10 more
doaj +2 more sources
BMC Ophthalmology, 2020 Background To study the therapeutic effect of bone marrow-derived mesenchymal stem cells (BMSC) against retinal neovascularization and to compare with anti-vascular endothelial growth factor (VEGF) therapy.
Wei Xu +3 more
doaj +2 more sources
Biology, 2021 Macular edema caused by retinal vascular leakage and ocular neovascularization are the leading causes of severe vision loss in diabetic retinopathy (DR) and age-related macular degeneration (AMD) patients.
Li Huang +6 more
doaj +2 more sources
Journal of Imaging, 2018 The pathological process of neovascularization of the retina plays a critical role in causing vision loss in several diseases, including diabetes, retinal vein occlusion, and sickle cell disease. Retinal neovascularization can lead to vitreous hemorrhage
Van Phuc Nguyen +5 more
doaj +2 more sources
Sea-fan retinal neovascularization associated with rickettsial retinitis: a case report [PDF]
BMC OphthalmologyBackground Rickettsial disease has been commonly associated with retinitis, retinal vasculitis, and optic nerve involvement, but the development of retinal neovascularization has been very rarely reported.
Nesrine Abroug +6 more
doaj +2 more sources
Retinal neovascularization in the setting of -mutation positive essential thrombocythemia [PDF]
SAGE Open Medical Case Reports, 2023 Patients with Calreticulin ( CALR ) mutation positive essential thrombocythemia are often thought of as having a “low-risk” of thrombotic complications.
Stanton P Heydinger +2 more
doaj +2 more sources
An allosteric peptide inhibitor of HIF-1α regulates hypoxia-induced retinal neovascularization
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Retinal ischemia causes hypoxia-induced neovascularization that stimulates production of proangiogenic cytokines such as VEGF by the hypoxia-inducible transcription factors HIF-1 and HIF-2.
Ayumi Usui‐Ouchi +7 more
openalex +3 more sources