Ferrochelatase regulates retinal neovascularization [PDF]
The FASEB Journal, 2020 AbstractFerrochelatase (FECH) is the terminal enzyme in heme biosynthesis. We previously showed that FECH is required for endothelial cell growth in vitro and choroidal neovascularization in vivo. But FECH has not been explored in retinal neovascularization, which underlies diseases like proliferative diabetic retinopathy and retinopathy of prematurity.
Sardar Pasha Sheik Pran Babu +2 more
openaire +5 more sources
IL-17A Enhances Retinal Neovascularization. [PDF]
Int J Mol Sci, 2023 Retinal neovascularization occurs in proliferative diabetic retinopathy, neovascular glaucoma, and age-related macular degeneration. This type of retinal pathology normally occurs in the later stages of these ocular diseases and is a prevalent cause of vision loss.
Taylor BE +7 more
europepmc +3 more sources
Sea-fan retinal neovascularization associated with rickettsial retinitis: a case report [PDF]
BMC OphthalmologyBackground Rickettsial disease has been commonly associated with retinitis, retinal vasculitis, and optic nerve involvement, but the development of retinal neovascularization has been very rarely reported.
Nesrine Abroug +6 more
doaj +2 more sources
Retinal neovascularization in the setting of -mutation positive essential thrombocythemia [PDF]
SAGE Open Medical Case Reports, 2023 Patients with Calreticulin ( CALR ) mutation positive essential thrombocythemia are often thought of as having a “low-risk” of thrombotic complications.
Stanton P Heydinger +2 more
doaj +2 more sources
Targeting Neuroinflammation in Neovascular Retinal Diseases [PDF]
Frontiers in Pharmacology, 2020 Retinal blood vessels provide the necessary energy, nutrients and oxygen in order to support visual function and remove harmful particles from blood, thus acting to protect neuronal cells.
Tianxi Wang +2 more
doaj +3 more sources
Peripheral retinal neovascularization in a patient with obstructive sleep apnea [PDF]
American Journal of Ophthalmology Case Reports, 2022 Purpose: To describe a case of peripheral retinal neovascularization and its possible etiological connection to comorbid obstructive sleep apnea. Observations: In this case report we describe a diabetic patient with obstructive sleep apnea who presented ...
Ravin Sajnani +4 more
doaj +2 more sources
A pilot optical coherence tomography angiography classification of retinal neovascularization in retinopathy of prematurity [PDF]
Scientific ReportsExtraretinal neovascularization is a hallmark of treatment-requiring retinopathy of prematurity (ROP). Optical coherence tomography angiography (OCTA) offers vascular flow and depth information not available from indirect ophthalmoscopy and structural ...
Xi Chen +10 more
doaj +2 more sources
Cyclic AMP Response Element Binding Protein Mediates Pathological Retinal Neovascularization via Modulating DLL4-NOTCH1 Signaling [PDF]
EBioMedicine, 2015 Retinal neovascularization is the most common cause of moderate to severe vision loss in all age groups. Despite the use of anti-VEGFA therapies, this complication continues to cause blindness, suggesting a role for additional molecules in retinal ...
Nikhlesh K. Singh +3 more
doaj +2 more sources
CM082 suppresses hypoxia-induced retinal neovascularization in larval zebrafish [PDF]
Frontiers in PharmacologyRetinal neovascularization is a common feature of several ocular neovascular diseases, which are the leading cause of blindness in the world. Current treatments are administered through invasive intravitreal injections, leading to poor patient compliance,
Jun-long Zhang +4 more
doaj +2 more sources
Peripapillary retinal neovascularization and vitreous hemorrhage secondary to peripapillary pachychoroid syndrome [PDF]
American Journal of Ophthalmology Case ReportsPurpose: To report a case of peripapillary pachychoroid syndrome (PPS) complicated with peripapillary retinal neovascularization causing vitreous hemorrhage.
Imène Zhioua Braham +4 more
doaj +2 more sources