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IL-17A Enhances Retinal Neovascularization. [PDF]
Int J Mol Sci, 2023 Retinal neovascularization occurs in proliferative diabetic retinopathy, neovascular glaucoma, and age-related macular degeneration. This type of retinal pathology normally occurs in the later stages of these ocular diseases and is a prevalent cause of vision loss.
Taylor BE +7 more
europepmc +4 more sources
Ferrochelatase regulates retinal neovascularization [PDF]
The FASEB Journal, 2020 AbstractFerrochelatase (FECH) is the terminal enzyme in heme biosynthesis. We previously showed that FECH is required for endothelial cell growth in vitro and choroidal neovascularization in vivo. But FECH has not been explored in retinal neovascularization, which underlies diseases like proliferative diabetic retinopathy and retinopathy of prematurity.
Sardar Pasha Sheik Pran Babu +2 more
openaire +5 more sources
VEGF-targeting drugs for the treatment of retinal neovascularization in diabetic retinopathy. [PDF]
Ann Med, 2022 Diabetic retinopathy (DR) is the most common microangiopathic complication of diabetes mellitus, representing a major cause of visual impairment in developed countries.
Arrigo A, Aragona E, Bandello F.
europepmc +2 more sources
MicroRNA-18a-5p Administration Suppresses Retinal Neovascularization by Targeting FGF1 and HIF1A
Frontiers in Pharmacology, 2020 Pathologic ocular neovascularization commonly results in visual impairment or even blindness in numerous fundus diseases, including proliferative diabetic retinopathy (PDR), retinopathy of prematurity (ROP), and age-related macular degeneration (AMD ...
Ji-Tian Guan +10 more
doaj +2 more sources
Targeting Neuroinflammation in Neovascular Retinal Diseases [PDF]
Frontiers in Pharmacology, 2020 Retinal blood vessels provide the necessary energy, nutrients and oxygen in order to support visual function and remove harmful particles from blood, thus acting to protect neuronal cells.
Tianxi Wang +2 more
doaj +3 more sources
BMC Ophthalmology, 2020 Background To study the therapeutic effect of bone marrow-derived mesenchymal stem cells (BMSC) against retinal neovascularization and to compare with anti-vascular endothelial growth factor (VEGF) therapy.
Wei Xu +3 more
doaj +2 more sources
Sea-fan retinal neovascularization associated with rickettsial retinitis: a case report [PDF]
BMC OphthalmologyBackground Rickettsial disease has been commonly associated with retinitis, retinal vasculitis, and optic nerve involvement, but the development of retinal neovascularization has been very rarely reported.
Nesrine Abroug +6 more
doaj +2 more sources
Retinal neovascularization in the setting of -mutation positive essential thrombocythemia [PDF]
SAGE Open Medical Case Reports, 2023 Patients with Calreticulin ( CALR ) mutation positive essential thrombocythemia are often thought of as having a “low-risk” of thrombotic complications.
Stanton P Heydinger +2 more
doaj +2 more sources
Biology, 2021 Macular edema caused by retinal vascular leakage and ocular neovascularization are the leading causes of severe vision loss in diabetic retinopathy (DR) and age-related macular degeneration (AMD) patients.
Li Huang +6 more
doaj +2 more sources
Cyclic AMP Response Element Binding Protein Mediates Pathological Retinal Neovascularization via Modulating DLL4-NOTCH1 Signaling [PDF]
EBioMedicine, 2015 Retinal neovascularization is the most common cause of moderate to severe vision loss in all age groups. Despite the use of anti-VEGFA therapies, this complication continues to cause blindness, suggesting a role for additional molecules in retinal ...
Nikhlesh K. Singh +3 more
doaj +2 more sources