Results 91 to 100 of about 402,915 (338)

Imatinib Ameliorated Retinal Neovascularization by Suppressing PDGFR-α and PDGFR-β

Cellular Physiology and Biochemistry, 2018
Background/Aims: Platelet-derived growth factors (PDGFs) have emerged as pivotal in pathological angiogenesis, which is a hallmark of various tumors and retinal diseases.
Lingli Zhou, Xiaowei Sun, Zijing Huang, Tian Zhou, Xiaowei Zhu, Yan Liu, Jing Wang, B. Cheng, Mei Li, Chang He, Xialin Liu   +10 more
semanticscholar   +1 more source

Inflammatory and angiogenic protein detection in the human vitreous : cytometric bead assay [PDF]

, 2011
Introduction. To evaluate clinical feasibility and reproducibility of cytometric bead assay (CBA) in nondiluted vitreous samples of patients with age-related macular degeneration (ARMD), diabetic macular edema (DME), and central retinal vein occlusion ...
Koch, Frank H., Koss, Michael Janusz, Pfister, Marcel   +2 more
core  

Vascular Response to Sildenafil Citrate in Aging and Age-Related Macular Degeneration. [PDF]

, 2019
Age-related macular degeneration (AMD) - the leading cause of vision loss in the elderly - share many risks factors as atherosclerosis, which exhibits loss of vascular compliance resulting from aging and oxidative stress.
Agrawal, Rupesh, Cheung, Chui Ming Gemmy, Cunefare, David, Farsiu, Sina, Khandelwal, Neha, Migacz, Justin, Tran, Steven, Vuong, Vivian S, Yiu, Glenn   +8 more
core   +2 more sources

Response of Experimental Retinal Neovascularization to Thiazolidinediones [PDF]

Archives of Ophthalmology, 2001
To determine the effect of thiazolidinediones (TZDs) on experimental retinal neovascularization.The ability of the TZDs troglitazone and rosiglitazone maleate (1-20 micromol/L) to inhibit retinal endothelial cell (REC) proliferation, migration, tube formation, and signaling was determined in response to vascular endothelial growth factor (VEGF).
T, Murata, Y, Hata, T, Ishibashi, S, Kim, W A, Hsueh, R E, Law, D R, Hinton   +6 more
openaire   +2 more sources

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Influence of silicone oil tamponade after vitrectomy on intraocular pressure [Tamponada silikonskim uljem i njezin utjecaj na vrijednosti intraokularnog tlaka] [PDF]

, 2013
The aim of this prospective study was to determine the possible influence of the silicone oil tamponade after vitrectomy on the early intraocular pressure (IOP) elevation, which is a major risk factor for developing secondary glaucoma in patients with ...
Barać, Josip, Biuk, Dubravka, Matić, Mate, Matić, Suzana, Popović Suić, Smiljka, Vinković, Maja   +5 more
core  

Computer-aided quantification of retinal neovascularization [PDF]

Angiogenesis, 2009
Rodent models of retinal angiogenesis play a pivotal role in angiogenesis research. These models are a window to developmental angiogenesis, to pathological retinopathy, and are also in vivo tools for anti-angiogenic drug screening in cancer and ophthalmic research.
Stahl, Andreas, Connor, Kip M., Sapieha, Przemyslaw, Willett, Keirnan L., Krah, Nathan M., Dennison, Roberta J., Chen, Jing, Guerin, Karen I., Smith, Lois E. H.   +8 more
openaire   +3 more sources

Characteristics of Retinal Neovascularization in Proliferative Diabetic Retinopathy Imaged by Optical Coherence Tomography Angiography.

Investigative Ophthalmology and Visual Science, 2016
Purpose To characterize the morphology of neovascularization at the disc (NVD) and neovascularization elsewhere (NVE) in treatment-naïve or previously treated proliferative diabetic retinopathy (PDR) patients using optical coherence tomography (OCT ...
Akihiro Ishibazawa, T. Nagaoka, H. Yokota, A. Takahashi, Tsuneaki Omae, Youngseok Song, Tatsuhisa Takahashi, A. Yoshida   +7 more
semanticscholar   +1 more source

Cost–benefit analysis of screening programme for diabetic retinopathy in Bulgaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Late‐diagnosed diabetic retinopathy (DR) is difficult and expensive to treat. Screening programmes can identify the disease early and reduce the costs of its future treatment. This study aims to analyse the cost–benefit of screening programmes for DR.
Iva Nenkova, Yoana Lilova, Alexander Oscar, Alina Levi, Maria Kamusheva, Guenka Petrova   +5 more
wiley   +1 more source

Formononetin, an active compound of Astragalus membranaceus (Fisch) Bunge, inhibits hypoxia-induced retinal neovascularization via the HIF-1α/VEGF signaling pathway

Drug Design, Development and Therapy, 2016
Background It has been reported that formononetin (FMN), one of the main ingredients from famous traditional Chinese medicine “Huang-qi” (Astragalus membranaceus [Fisch] Bunge) for Qi-tonifying, exhibits the effects of immunomodulation and tumor growth ...
Jianming Wu, Xiao Ke, Na Ma, Wei Wang, Weiding Fu, Hongcheng Zhang, Man-xi Zhao, Xiaoping Gao, Xiaofeng Hao, Zhirong Zhang   +9 more
semanticscholar   +1 more source