Results 91 to 100 of about 385,405 (300)
FGF21 Administration Suppresses Retinal and Choroidal Neovascularization in Mice
Cell Reports, 2017 Pathological neovascularization, a leading cause of blindness, is seen in retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration.
Zhongjie Fu +12 more
doaj +1 more source
Dietary Compound Chrysin Inhibits Retinal Neovascularization with Abnormal Capillaries in db/db Mice
Nutrients, 2016 Diabetic retinopathy (DR) develops in a significant proportion of patients with chronic diabetes, characterized by retinal macular edema and abnormal retinal vessel outgrowth leading to vision loss.
Min-Kyung Kang +7 more
semanticscholar +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose The retinal pigment epithelium (RPE) is critical in the pathophysiology of retinal diseases, such as age‐related macular degeneration. Adaptive optics transscleral flood illumination (AO‐TFI) offers rapid, detailed morphometric characterization of the RPE layer.
Leila Sara Eppenberger +8 more
wiley +1 more source
The Long-Noncoding RNA TUG1 Regulates Oxygen-Induced Retinal Neovascularization in Mice via MiR-299
, 2022 Yue Wang +4 more
openalex +1 more source
Axial length, myopia progression, and myopic maculopathy in Stickler syndrome
Acta Ophthalmologica, EarlyView.Abstract Purpose We lack knowledge on the potentially progressive nature of and the prevalence of complications to myopia as a characteristic trait of Stickler syndrome. Methods This cross‐sectional study combines ophthalmic examination and medical record data on Danish patients with genetically confirmed Stickler syndrome type 1 (COL2A1) and type 2 ...
Kirstine B. Boysen +4 more
wiley +1 more source
Retinal neovascularization and its therapeutic agents
Folia Pharmacologica Japonica, 2010 増殖糖尿病網膜症（proliferative diabetic retinopathy : PDR），未熟児網膜症，網膜静脈閉塞症および加齢黄斑変性症（age-related macular degen-eration : AMD）などの後眼部疾患は，網膜における病的な血管新生により惹起される疾患で不可逆的な視野欠損や失明を引き起こす．しかし，これまでこれら疾患に対する有効な治療薬はなく，その網膜血管新生を阻害する薬剤の開発が試みられてきた．近年，強力な血管新生促進因子として血管内皮細胞増殖因子（vascular endothelial growth factor : VEGF）が同定され，さらにPDRおよびAMDの発症に深く関与していることが明らかにされ ...
Shinsuke, Nakamura +2 more
openaire +3 more sources
Acta Ophthalmologica, EarlyView.Abstract Purpose To evaluate longitudinal changes in choroidal thickness (CT) in highly myopic eyes and their correlation with myopic maculopathy progression and visual outcomes. Methods Retrospective cohort study on 1228 eyes from 781 highly myopic patients with a minimum 5‐year follow‐up (mean 11.5 ± 3.1 years).
Matteo Mario Carlà +8 more
wiley +1 more source
The prechoroidal cleft in neovascular age‐related macular degeneration
Acta Ophthalmologica, EarlyView.Abstract The prechoroidal cleft is a lenticular, hypo‐reflective space on optical coherence tomography imaging, located between a band of fibrovascular material underneath the retinal pigment epithelium (RPE) and Bruch's membrane. It occurs in 8%–22% of neovascular age‐related macular degeneration (nAMD) eyes, most often with macular neovascularization
Niels J. Brouwer +3 more
wiley +1 more source
Vitreoretinal complications and surgical outcomes in patients with X‐linked retinoschisis
Acta Ophthalmologica, EarlyView.Abstract Purpose X‐linked retinoschisis (XLRS) is an inherited vitreoretinal disorder characterized by macular retinoschisis. In a subgroup of patients, peripheral retinoschisis can occur, potentially leading to complications such as vitreous haemorrhage (VH) and retinal detachment (RD).
Jonathan Hensman +11 more
wiley +1 more source