Results 91 to 100 of about 396,361 (329)

Integrated results from the COPERNICUS and GALILEO studies. [PDF]

, 2017
OBJECTIVES: To report on the efficacy and safety of intravitreal aflibercept in patients with macular edema secondary to central retinal vein occlusion (CRVO) in an integrated analysis of COPERNICUS and GALILEO.
Ahlers, Christiane, Asmus, Friedrich, Boyer, David S., Clark, W. Lloyd, Haller, Julia A., Holz, Frank G., Korobelnik, Jean-Francois, Ogura, Yuichiro, Pielen, Amelie, Rittenhouse, Kay D., Saroj, Namrata, Stemper, Brigitte, Vitti, Robert, Zeitz, Oliver   +13 more
core   +3 more sources

AGAPIR: A Novel PIWI‐Interacting RNA Enhancing Post‐Decompression Angiogenesis in Degenerative Cervical Myelopathy

Advanced Science, EarlyView.
The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie, Yiling Peng, Tianyu Qin, Cuimei Chen, Zhenxiao Ren, Naibo Feng, Chungeng Liu, Songlin Peng, Houqing Long   +8 more
wiley   +1 more source

Diverse roles of macrophages in intraocular neovascular diseases: a review [PDF]

International Journal of Ophthalmology, 2017
Macrophages are involved in angiogenesis, and might also contribute to the pathogenesis of intraocular neovascular diseases. Recent studies indicated that macrophages exert different functions in the process of intraocular neovascularization, and the ...
Ye-Di Zhou, Shigeo Yoshida, Ying-Qian Peng, Yoshiyuki Kobayashi, Lu-Si Zhang, Luo-Sheng Tang   +5 more
doaj   +1 more source

Nanoparticle Drug Delivery Systems for Atherosclerosis: Precision Targeting, Inflammatory Modulation, and Plaque Stabilization

Advanced Science, EarlyView.
This review first summarizes the complex pathogenesis of atherosclerosis and outlines the limitations of conventional therapies. It then explores innovative nanoparticle drug delivery system (NDDS) developments, detailing their precision targeting strategies, responsiveness to plaque‐specific stimuli, modulation of key pathological processes, and ...
Yunqi Zhang, Feifei Li, Libo Liu, Ziyu An, Hanzhong Luo, Huan Zhang, Rui Ma, Ruoxi Zhang, Qiong Dai, Mingduo Zhang, Jinfan Tian, Chaoyong Liu, Xiantao Song, Yunfeng Lu   +13 more
wiley   +1 more source

Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation. [PDF]

, 2019
Blood vessels in the central nervous system (CNS) develop unique features, but the contribution of CNS neurons to regulating those features is not fully understood. We report that inhibiting spontaneous cholinergic activity or reducing starburst amacrine
Angelopoulos, CM, Bartakova, AB, Daneman, R, Goldberg, JL, Murphy, A, Nudleman, E, Pulido, RS, Shah, SH, Weiner, GA   +8 more
core   +1 more source

Response of Experimental Retinal Neovascularization to Thiazolidinediones [PDF]

Archives of Ophthalmology, 2001
To determine the effect of thiazolidinediones (TZDs) on experimental retinal neovascularization.The ability of the TZDs troglitazone and rosiglitazone maleate (1-20 micromol/L) to inhibit retinal endothelial cell (REC) proliferation, migration, tube formation, and signaling was determined in response to vascular endothelial growth factor (VEGF).
Willa A. Hsueh, Sarah Kim, Yasuaki Hata, David R. Hinton, David R. Hinton, Tatsuro Ishibashi, Ronald E. Law, Toshinori Murata   +7 more
openaire   +2 more sources

Mainstream Artificial Intelligence Technologies in Contemporary Ophthalmology

Advanced Intelligent Systems, EarlyView.
This review explores the latest artificial intelligence (AI) technologies in ophthalmology, focusing on four key data types: medical imaging, electronic health records, robotic‐assisted surgery, and genomics. It examines the structural features, use cases, clinical goals, and evaluation metrics of various AI algorithms, while also introducing emerging ...
Shiqi Yin, Lei Wang, Shanjun Wu, Jiewei Jiang, Wei Qiang, Yangyang Wang, Shihong Wang, Yi Shao, Wei Chen, Zhongwen Li   +9 more
wiley   +1 more source

Wide-field angiography in retinal vein occlusions

International Journal of Retina and Vitreous, 2019
Background Retinal vein occlusion (RVO) is the second most common retinal vascular disease after diabetic retinopathy. It can result in significant visual loss from complications like macula edema, retinal and iris neovascularization, and vitreous ...
Colin S. Tan, Kelvin Z. Li, SriniVas R. Sadda   +2 more
doaj   +1 more source

Formononetin, an active compound of Astragalus membranaceus (Fisch) Bunge, inhibits hypoxia-induced retinal neovascularization via the HIF-1α/VEGF signaling pathway

Drug Design, Development and Therapy, 2016
Background It has been reported that formononetin (FMN), one of the main ingredients from famous traditional Chinese medicine “Huang-qi” (Astragalus membranaceus [Fisch] Bunge) for Qi-tonifying, exhibits the effects of immunomodulation and tumor growth ...
Jianming Wu, Xiao Ke, Na Ma, Wei Wang, Weiding Fu, Hongcheng Zhang, Man-xi Zhao, Xiaoping Gao, Xiaofeng Hao, Zhirong Zhang   +9 more
semanticscholar   +1 more source

Vascular Response to Sildenafil Citrate in Aging and Age-Related Macular Degeneration. [PDF]

, 2019
Age-related macular degeneration (AMD) - the leading cause of vision loss in the elderly - share many risks factors as atherosclerosis, which exhibits loss of vascular compliance resulting from aging and oxidative stress.
Agrawal, Rupesh, Cheung, Chui Ming Gemmy, Cunefare, David, Farsiu, Sina, Khandelwal, Neha, Migacz, Justin, Tran, Steven, Vuong, Vivian S, Yiu, Glenn   +8 more
core   +2 more sources