Results 121 to 130 of about 370,441 (288)

A Dark and Bright Channel Prior Guided Deep Network for Retinal Image Quality Assessment [PDF]

arXiv, 2020
Retinal image quality assessment is an essential task in the diagnosis of retinal diseases. Recently, there are emerging deep models to grade quality of retinal images. Current state-of-the-arts either directly transfer classification networks originally designed for natural images to quality classification of retinal images or introduce extra image ...
arxiv  

Fenofibrate Inhibits Cytochrome P450 Epoxygenase 2C Activity to Suppress Pathological Ocular Angiogenesis

EBioMedicine, 2016
Neovascular eye diseases including retinopathy of prematurity, diabetic retinopathy and age-related-macular-degeneration are major causes of blindness.
Yan Gong, Zhuo Shao, Zhongjie Fu, Matthew L. Edin, Ye Sun, Raffael G. Liegl, Zhongxiao Wang, Chi-Hsiu Liu, Samuel B. Burnim, Steven S. Meng, Fred B. Lih, John Paul SanGiovanni, Darryl C. Zeldin, Ann Hellström, Lois E.H. Smith   +14 more
doaj   +1 more source

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins.

Proceedings of the National Academy of Sciences of the United States of America, 1995
The majority of severe visual loss in the United States results from complications associated with retinal neovascularization in patients with ischemic ocular diseases such as diabetic retinopathy, retinal vein occlusion, and retinopathy of prematurity ...
L. P. Aiello, E. Pierce, E. D. Foley, H. Takagi, Helen Chen, L. Riddle, N. Ferrara, G. King, L. Smith   +8 more
semanticscholar   +1 more source

Adalimumab Monotherapy or Combination Therapy With Methotrexate in Paediatric Uveitis: Data From the AIDA Network Uveitis Registry

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background The study objective was to compare the effectiveness of adalimumab (ADA) in monotherapy and in combination with methotrexate (MTX) for paediatric noninfectious uveitis (NIU). Methods Registry‐based observational study. Children receiving ADA for active uveitis were divided into the ADA monotherapy group (group 1) and the ADA plus ...
Carla Gaggiano, Alejandra de‐la‐Torre, Silvana Guerriero, Stefania Costi, Gaafar Ragab, Maria Pia Paroli, Emanuela Del Giudice, Luciana Breda, Saverio La Bella, Marco Cattalini, Maria Cristina Maggio, Alex Fonollosa, Ester Carreño, Maria Tarsia, Rosanna Dammacco, Soad Hashad, Antonio Vitale, Lampros Fotis, Stefano Gentileschi, Francesca Minoia, Germán Mejía‐Salgado, Halah Etayari, Paola Saboya‐Galindo, María Andrea Bernal‐Valencia, Adele Civino, Maria Sole Chimenti, Valeria Caggiano, Maria Francesca Gicchino, Jurgen Sota, Angela Mauro, Giuseppe Lopalco, Kalpana Babu Murthy, Mohamed Tharwat Hegazy, Vishali Gupta, Francesco La Torre, Rana Hussein Amin, Bruno Frediani, Gian Marco Tosi, Luca Cantarini, Claudia Fabiani, on behalf of the AIDA Network   +40 more
wiley   +1 more source

Spectrum of peripheral retinal ischemia in Wyburn-Mason syndrome

American Journal of Ophthalmology Case Reports, 2020
Purpose: We report two cases of Wyburn-Mason syndrome that illustrate the spectrum of peripheral retinal ischemia seen in this condition. Observations: A 12-year-old female presented with a retinal arteriovenous malformation and sclerotic vessels ...
Blake Fortes, MD, James Lin, MD, Supalert Prakhunhungsit, MD, Carlos Mendoza-Santiesteban, MD, Audina M. Berrocal, MD   +4 more
doaj  

Cytochrome P450 Oxidase 2C Inhibition Adds to &ohgr;-3 Long-Chain Polyunsaturated Fatty Acids Protection Against Retinal and Choroidal Neovascularization

Arteriosclerosis, Thrombosis and Vascular Biology, 2016
Objective—Pathological ocular neovascularization is a major cause of blindness. Increased dietary intake of &ohgr;-3 long-chain polyunsaturated fatty acids (LCPUFA) reduces retinal neovascularization and choroidal neovascularization (CNV), but &ohgr;-3 ...
Y. Gong, Z. Fu, M. Edin, Chi-Hsiu Liu, Zhongxiao Wang, Z. Shao, Thomas W Fredrick, Nicholas J. Saba, P. Morss, Samuel B Burnim, Steven S Meng, F. Lih, K. S. Lee, Elizabeth P. Moran, J. Sangiovanni, A. Hellström, B. Hammock, D. Zeldin, Lois E. H. Smith   +18 more
semanticscholar   +1 more source

Retinal Vessel Segmentation Using A New Topological Method [PDF]

arXiv, 2016
A novel topological segmentation of retinal images represents blood vessels as connected regions in the continuous image plane, having shape-related analytic and geometric properties. This paper presents topological segmentation results from the DRIVE retinal image database.
arxiv  

Overexpression of Vascular Endothelial Growth Factor (VEGF) in the Retinal Pigment Epithelium Leads to the Development of Choroidal Neovascularization [PDF]

, 2000
Katrina Spilsbury, Kerryn L. Garrett, Wei-Yong Shen, Ian J. Constable, Piroska E. Rakoczy   +4 more
openalex   +1 more source

MicroRNA-410 Reduces the Expression of Vascular Endothelial Growth Factor and Inhibits Oxygen-Induced Retinal Neovascularization

PLoS ONE, 2014
Retinal neovascularization (RNV) is an eye disease that can cause retinal detachment and even lead to blindness. RNV mainly occurs in the elderly population.
Na Chen, Jiaqi Wang, Yijun Hu, Bei Cui, Wenjie Li, Guixia Xu, Lin Liu, Shanrong Liu   +7 more
semanticscholar   +1 more source

Mesenchymal Stem Cell‐Derived Exosomes: A Promising Therapeutic Strategy for Age‐Related Diseases

Cell Proliferation, EarlyView.
Mechanisms of MSC‐Exos in the treatment of age‐related diseases. A Immunomodulatory and anti‐inflammatory, MSC‐Exos mediate immunomodulatory and anti‐inflammatory effects by regulating the polarisation of T cells and macrophages, promoting an anti‐inflammatory state while inhibiting pro‐inflammatory responses; B Suppression of oxidative stress, MSC ...
Bohua Wei, Mengting Wei, Haonan Huang, Ting Fan, Zhichang Zhang, Xiaoyu Song   +5 more
wiley   +1 more source