Results 121 to 130 of about 385,405 (300)

Squalamine improves retinal neovascularization.

Investigative ophthalmology & visual science, 2000
Modalities for inhibiting neovascularization may be one avenue to the development of effective therapies for retinopathy. The effect of squalamine, an antiangiogenic amino sterol, on oxygen-induced retinopathy (OIR) was assessed in a mouse model.OIR was induced in C57BL6 mice by a 5-day exposure to 75% oxygen from postnatal day (P)7 through P12 ...
R D, Higgins, R J, Sanders, Y, Yan, M, Zasloff, J I, Williams   +4 more
openaire   +1 more source

Intraocular Osseous Metaplasia in Norfolk Black Turkey (Meleagris gallopavo): Clinicopathological Characterization of a Rare Avian Condition

Veterinary Ophthalmology, EarlyView.
ABSTRACT Background Osseous metaplasia is a rare condition characterized by abnormal bone growth in soft tissues. Although documented in mammals, intraocular osseous metaplasia is uncommon in avian species and has been poorly characterized in turkeys (Meleagris gallopavo).
Taina dos Santos Alberti, Andressa Trindade Nogueira, Magale Dallaporta Furquim, Driele Fernanda dos Santos, Rosimeri Zamboni, Eliza Simone Viégas Sallis, Clairton Marcolongo‐Pereira   +6 more
wiley   +1 more source

The roles of macrophage migration inhibitory factor in retinal diseases

Neural Regeneration Research
Macrophage migration inhibitory factor (MIF), a multifunctional cytokine, is secreted by various cells and participates in inflammatory reactions, including innate and adaptive immunity. There are some evidences that MIF is involved in many vitreoretinal
Hongbing Zhang, Xianjiao Zhang, Hongsong Li, Bing Wang, Pei Chen, Jiamin Meng   +5 more
doaj   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Overexpression of Vascular Endothelial Growth Factor (VEGF) in the Retinal Pigment Epithelium Leads to the Development of Choroidal Neovascularization [PDF]

, 2000
Katrina Spilsbury, Kerryn L. Garrett, Wei-Yong Shen, Ian J. Constable, Piroska E. Rakoczy   +4 more
openalex   +1 more source

A 66‐year‐old man with acute retinal necrosis

Brain Pathology, EarlyView.
Shino Magaki, Fausto J. Rodriguez, Matthew Koo, Colin A. McCannel   +3 more
wiley   +1 more source

MSC‐Derived Exosomal lnc‐AGT‐3: A Novel Anti‐Angiogenic Target in Age‐Related Macular Degeneration Through p53 Signaling Pathway

Aging Cell, Volume 25, Issue 2, February 2026.
MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong, Xiaoyan Han, Siyi Qi, Duo Li, Jingyue Zhang, Linyu Zhang, Shujie Zhang, Qin Jiang, Biao Yan, Chen Zhao   +9 more
wiley   +1 more source

Phenotyping of retinal neovascularization in ischemic retinal vein occlusion using wide field OCT angiography

Eye, 2020
Josef Huemer, Hagar Khalid, S. Wagner, L. Nicholson, D. J. Fu, D. Sim, P. Patel, K. Balaskas, R. Rajendram, P. Keane   +9 more
semanticscholar   +1 more source

Intravitreal anti‐vascular endothelial growth factor injections and risks of stroke in patients with neovascular age‐related macular degeneration—A registry‐based cohort study

Acta Ophthalmologica, Volume 104, Issue 1, Page 98-105, February 2026.
Abstract Background Intravitreal Anti‐Vascular Endothelial Growth Factor (VEGF) rescues retinal vasculatures and prevents disease progression in patients with neovascular Age‐Related Macular Degeneration (nAMD). However, systemic anti‐VEGF may increase the risk of thromboembolic related complications including stroke and TIA. This study aims to explore
A. H. Falemban, K. Söderberg‐Löfdal, F. Jonsson, S. Almlöf‐Sarman, M. von Euler, I. Westborg   +5 more
wiley   +1 more source

Comparison of the Effects of the Pattern Scan and Conventional Single Spot Panretinal Photocoagulation in Patients with Proliferative Diabetic Retinopathy; A Randomized Clinical Trial

مجله دانشکده پزشکی اصفهان, 2016
Background: The retinal laser photocoagulation is the gold standard treatment of the proliferative diabetic retinopathy. Nowadays, we can perform panretinal photocoagulation with single spot or pattern scan laser methods.
Alireza Jamshidimadad, Alireza Dehghani, Farzan Kianersi, Khodayar Golabchi, Heshmatollah Ghanbari, Mohamadreza Akhlaghi   +5 more
doaj