eLife, 2019 Constitutive TGFβ signaling is important in maintaining retinal neurons and blood vessels and is a factor contributing to the risk for age-related macular degeneration (AMD), a retinal disease involving neurodegeneration and microglial activation.
Wenxin Ma +6 more
doaj +2 more sources
Effects of nuclear factor κB expression on retinal neovascularization and apoptosis in a diabetic retinopathy rat model [PDF]
International Journal of Ophthalmology, 2015 AIM:To investigate the expression and role of nuclear factor κB (NF-κB) in diabetic retinopathy (DR) and its relationship with neovascularization and retinal cell apoptosis.METHODS: A total of 80 male Wistar rats were randomly assigned to control (4, 8 ...
Ning Jiang +3 more
doaj +2 more sources
VEGF-targeting drugs for the treatment of retinal neovascularization in diabetic retinopathy. [PDF]
Ann Med, 2022 Diabetic retinopathy (DR) is the most common microangiopathic complication of diabetes mellitus, representing a major cause of visual impairment in developed countries.
Arrigo A, Aragona E, Bandello F.
europepmc +2 more sources
Retinal neovascularization in the setting of CALR-mutation positive essential thrombocythemia. [PDF]
SAGE Open Med Case Rep, 2023 Patients with Calreticulin ( CALR ) mutation positive essential thrombocythemia are often thought of as having a “low-risk” of thrombotic complications.
Heydinger SP, Abdulaal MR, Wang AL.
europepmc +2 more sources
Sea-fan retinal neovascularization associated with rickettsial retinitis: a case report. [PDF]
BMC OphthalmolBackground Rickettsial disease has been commonly associated with retinitis, retinal vasculitis, and optic nerve involvement, but the development of retinal neovascularization has been very rarely reported.
Abroug N +6 more
europepmc +2 more sources
IL-17A Enhances Retinal Neovascularization. [PDF]
Int J Mol Sci, 2023 Retinal neovascularization occurs in proliferative diabetic retinopathy, neovascular glaucoma, and age-related macular degeneration. This type of retinal pathology normally occurs in the later stages of these ocular diseases and is a prevalent cause of vision loss.
Taylor BE +7 more
europepmc +3 more sources
Peripheral retinal neovascularization in a patient with obstructive sleep apnea. [PDF]
Am J Ophthalmol Case Rep, 2022 Purpose: To describe a case of peripheral retinal neovascularization and its possible etiological connection to comorbid obstructive sleep apnea. Observations: In this case report we describe a diabetic patient with obstructive sleep apnea who presented ...
Sajnani R +4 more
europepmc +2 more sources
Ocular Syphilis with Retinal and Disc Neovascularization Treated with Bevacizumab: A Case Report
Case Reports in Ophthalmology, 2023 We report the findings observed in a young woman with ocular syphilis complicated with retinal and disc neovascularization successfully treated with intravitreal bevacizumab.
Lucia Comastri +4 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2023 Microglia are the primary resident retinal macrophages that monitor neuronal activity in real-time and facilitate angiogenesis during retinal development. In certain retinal diseases, the activated microglia promote retinal angiogenesis in hypoxia stress
Xue-Yan Fu +5 more
semanticscholar +1 more source
A pilot optical coherence tomography angiography classification of retinal neovascularization in retinopathy of prematurity. [PDF]
Sci RepExtraretinal neovascularization is a hallmark of treatment-requiring retinopathy of prematurity (ROP). Optical coherence tomography angiography (OCTA) offers vascular flow and depth information not available from indirect ophthalmoscopy and structural ...
Chen X +10 more
europepmc +2 more sources