Results 11 to 20 of about 38,468 (270)

Intravitreal Aflibercept as a Rescue Therapy for Retinal Neovascularization and Macular Edema due to Eales Disease [PDF]

open access: goldCase Reports in Ophthalmological Medicine, 2021
We report the rescue effect of intravitreal aflibercept injections on retinal neovascularization and macular edema due to Eales disease. Case 1 was a 36-year-old female. Intravitreal aflibercept was administered as rescue therapy after persistent retinal
Ning-Yi Hsia   +6 more
doaj   +2 more sources

Ferrochelatase regulates retinal neovascularization [PDF]

open access: yesThe FASEB Journal, 2020
Abstract Ferrochelatase (FECH) is the terminal enzyme in heme biosynthesis. We previously showed that FECH is required for endothelial cell growth in vitro and choroidal neovascularization in vivo. But FECH has not been explored in retinal neovascularization, which underlies diseases like proliferative diabetic ...
Sardar Pasha Sheik Pran Babu   +2 more
openaire   +3 more sources

Peripheral retinal neovascularization in a patient with obstructive sleep apnea

open access: yesAmerican Journal of Ophthalmology Case Reports, 2022
Purpose: To describe a case of peripheral retinal neovascularization and its possible etiological connection to comorbid obstructive sleep apnea. Observations: In this case report we describe a diabetic patient with obstructive sleep apnea who presented ...
Ravin Sajnani   +4 more
doaj   +1 more source

The progress of prophylactic treatment in retinopathy of prematurity [PDF]

open access: yesInternational Journal of Ophthalmology, 2018
Retinopathy of prematurity (ROP) is a retinal vascular disorder frequently found in premature infants. Different therapeutic strategies have been developed to treat ROP.
Hong-Bing Zhang   +3 more
doaj   +1 more source

An Endostatin-lentivirus (ES-LV)-EPC gene therapy agent for suppression of neovascularization in oxygen-induced retinopathy rat model

open access: yesBMC Molecular and Cell Biology, 2020
Background Transplantation of gene transfected endothelial progenitor cells (EPCs) has provided novel methods for tumor neovascularization therapy but not for ocular disease therapy.
Jing Ai   +4 more
doaj   +1 more source

YY1 lactylation in microglia promotes angiogenesis through transcription activation-mediated upregulation of FGF2

open access: yesGenome Biology, 2023
Background Ocular neovascularization is a leading cause of blindness. Retinal microglia have been implicated in hypoxia-induced angiogenesis and vasculopathy, but the underlying mechanisms are not entirely clear.
Xiaotang Wang   +10 more
doaj   +1 more source

Downregulation of PIK3IP1 in retinal microglia promotes retinal pathological neovascularization via PI3K-AKT pathway activation

open access: yesScientific Reports, 2023
Retinal pathological neovascularization involves endothelial cells, pericytes, photoreceptor cells, ganglion cells, and glial cells, whose roles remain unclear.
Lushu Chen   +5 more
doaj   +1 more source

Ref-1 redox activity regulates retinal neovascularization by modulating transcriptional activation of HIF-1α. [PDF]

open access: hybridFASEB J
Hartman GD   +12 more
europepmc   +2 more sources

Deletion of LRP5 in VLDLR knockout mice inhibits retinal neovascularization. [PDF]

open access: yesPLoS ONE, 2013
The development and maintenance of retinal vasculature require a precise balance between pro-angiogenic and anti-angiogenic factors. However, mechanisms underlying normal homeostasis of retinal vasculature and pathological changes of disrupted retinal ...
Chun-hong Xia   +3 more
doaj   +1 more source

Vitamin D receptor expression is essential during retinal vascular development and attenuation of neovascularization by 1, 25(OH)2D3. [PDF]

open access: yesPLoS ONE, 2017
Vitamin D provides a significant benefit to human health, and its deficiency has been linked to a variety of diseases including cancer. Vitamin D exhibits anticancer effects perhaps through inhibition of angiogenesis. We previously showed that the active
Nasim Jamali   +4 more
doaj   +1 more source

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