Results 11 to 20 of about 385,405 (300)

Vitamin D receptor expression is essential during retinal vascular development and attenuation of neovascularization by 1, 25(OH)2D3. [PDF]

PLoS ONE, 2017
Vitamin D provides a significant benefit to human health, and its deficiency has been linked to a variety of diseases including cancer. Vitamin D exhibits anticancer effects perhaps through inhibition of angiogenesis. We previously showed that the active
Nasim Jamali, Shoujian Wang, Soesiawati R Darjatmoko, Christine M Sorenson, Nader Sheibani   +4 more
doaj   +2 more sources

Targeting Neuroinflammation in Neovascular Retinal Diseases [PDF]

Frontiers in Pharmacology, 2020
Retinal blood vessels provide the necessary energy, nutrients and oxygen in order to support visual function and remove harmful particles from blood, thus acting to protect neuronal cells.
Tianxi Wang, Demetrios I. Tsirukis, Ye Sun   +2 more
doaj   +3 more sources

A pilot optical coherence tomography angiography classification of retinal neovascularization in retinopathy of prematurity [PDF]

Scientific Reports
Extraretinal neovascularization is a hallmark of treatment-requiring retinopathy of prematurity (ROP). Optical coherence tomography angiography (OCTA) offers vascular flow and depth information not available from indirect ophthalmoscopy and structural ...
Xi Chen, Ryan Imperio, Christian Viehland, Pujan R. Patel, Du Tran-Viet, Shwetha Mangalesh, S. Grace Prakalapakorn, Sharon F. Freedman, Joseph A. Izatt, Cynthia A. Toth, BabySTEPS Group   +10 more
doaj   +2 more sources

CM082 suppresses hypoxia-induced retinal neovascularization in larval zebrafish [PDF]

Frontiers in Pharmacology
Retinal neovascularization is a common feature of several ocular neovascular diseases, which are the leading cause of blindness in the world. Current treatments are administered through invasive intravitreal injections, leading to poor patient compliance,
Jun-long Zhang, Ding-gang Fan, Wu Yin, Wu Yin, Bing Hu   +4 more
doaj   +2 more sources

Accelerated oxygen-induced retinopathy is a reliable model of ischemia-induced retinal neovascularization.

PLoS ONE, 2017
Retinal ischemia and pathological angiogenesis cause severe impairment of sight. Oxygen-induced retinopathy (OIR) in young mice is widely used as a model to investigate the underlying pathological mechanisms and develop therapeutic interventions.
Pilar Villacampa, Katja E Menger, Laura Abelleira, Joana Ribeiro, Yanai Duran, Alexander J Smith, Robin R Ali, Ulrich F Luhmann, James W B Bainbridge   +8 more
doaj   +2 more sources

Peripapillary retinal neovascularization and vitreous hemorrhage secondary to peripapillary pachychoroid syndrome [PDF]

American Journal of Ophthalmology Case Reports
Purpose: To report a case of peripapillary pachychoroid syndrome (PPS) complicated with peripapillary retinal neovascularization causing vitreous hemorrhage.
Imène Zhioua Braham, Mejdi Boukari, Rim Maalej, Ilhem Mili, Raja Zhioua   +4 more
doaj   +2 more sources

BARD1-mediated stabilization of METTL14 promotes retinal neovascularization by m6A-modifying MXD1 mRNA on a YTHDF2-dependent manner. [PDF]

Theranostics
Liu X, Zeng S, Meng J, Zhou Q, Cao F, Chu B, Wu C, Wang Y, Feng H, Bi X, Chen X, Yang W, Tian M, Yang H, Hu K, Hou S.   +15 more
europepmc   +3 more sources

Ocular Syphilis with Retinal and Disc Neovascularization Treated with Bevacizumab: A Case Report

Case Reports in Ophthalmology, 2023
We report the findings observed in a young woman with ocular syphilis complicated with retinal and disc neovascularization successfully treated with intravitreal bevacizumab.
Lucia Comastri, Milagros Heredia, Diego Bar, Guillermo Iribarren, Ariel Schlaen   +4 more
doaj   +1 more source

VEGF-targeting drugs for the treatment of retinal neovascularization in diabetic retinopathy

Annals medicus, 2022
Diabetic retinopathy (DR) is the most common microangiopathic complication of diabetes mellitus, representing a major cause of visual impairment in developed countries.
A. Arrigo, Emanuela Aragona, F. Bandello
semanticscholar   +1 more source

Ferulic acid alleviates retinal neovascularization by modulating microglia/macrophage polarization through the ROS/NF-κB axis

Frontiers in Immunology, 2022
Inflammation plays a pivotal role in ischemia-induced retinal neovascularization. Targeting microglia/macrophage-based neuroinflammation presents a promising therapeutic strategy.
Xiaowei Sun, Lusheng Ma, Xiao Li, Jiao Wang, Yuanbin Li, Zijing Huang   +5 more
semanticscholar   +1 more source