Results 11 to 20 of about 396,361 (329)
Ferrochelatase regulates retinal neovascularization [PDF]
The FASEB Journal, 2020 AbstractFerrochelatase (FECH) is the terminal enzyme in heme biosynthesis. We previously showed that FECH is required for endothelial cell growth in vitro and choroidal neovascularization in vivo. But FECH has not been explored in retinal neovascularization, which underlies diseases like proliferative diabetic retinopathy and retinopathy of prematurity.
Sardar Pasha Sheik Pran Babu +2 more
openaire +5 more sources
VEGF-targeting drugs for the treatment of retinal neovascularization in diabetic retinopathy. [PDF]
Ann Med, 2022 Diabetic retinopathy (DR) is the most common microangiopathic complication of diabetes mellitus, representing a major cause of visual impairment in developed countries.
Arrigo A, Aragona E, Bandello F.
europepmc +2 more sources
MicroRNA-18a-5p Administration Suppresses Retinal Neovascularization by Targeting FGF1 and HIF1A
Frontiers in Pharmacology, 2020 Pathologic ocular neovascularization commonly results in visual impairment or even blindness in numerous fundus diseases, including proliferative diabetic retinopathy (PDR), retinopathy of prematurity (ROP), and age-related macular degeneration (AMD ...
Ji-Tian Guan +10 more
doaj +2 more sources
Targeting Neuroinflammation in Neovascular Retinal Diseases [PDF]
Frontiers in Pharmacology, 2020 Retinal blood vessels provide the necessary energy, nutrients and oxygen in order to support visual function and remove harmful particles from blood, thus acting to protect neuronal cells. The homeostasis of the retinal vessels is important for the maintenance of retinal visual function.
Ye Sun +2 more
openaire +4 more sources
Peripheral retinal neovascularization in a patient with obstructive sleep apnea [PDF]
American Journal of Ophthalmology Case Reports, 2022 Purpose: To describe a case of peripheral retinal neovascularization and its possible etiological connection to comorbid obstructive sleep apnea. Observations: In this case report we describe a diabetic patient with obstructive sleep apnea who presented ...
Ravin Sajnani +4 more
doaj +2 more sources
Biology, 2021 Macular edema caused by retinal vascular leakage and ocular neovascularization are the leading causes of severe vision loss in diabetic retinopathy (DR) and age-related macular degeneration (AMD) patients.
Li Huang +6 more
doaj +2 more sources
Journal of Imaging, 2018 The pathological process of neovascularization of the retina plays a critical role in causing vision loss in several diseases, including diabetes, retinal vein occlusion, and sickle cell disease. Retinal neovascularization can lead to vitreous hemorrhage
Van Phuc Nguyen +5 more
doaj +2 more sources
Retinal neovascularization in the setting of -mutation positive essential thrombocythemia [PDF]
SAGE Open Medical Case Reports, 2023 Patients with Calreticulin ( CALR ) mutation positive essential thrombocythemia are often thought of as having a “low-risk” of thrombotic complications.
Stanton P Heydinger +2 more
doaj +2 more sources
Sea-fan retinal neovascularization associated with rickettsial retinitis: a case report [PDF]
BMC OphthalmologyBackground Rickettsial disease has been commonly associated with retinitis, retinal vasculitis, and optic nerve involvement, but the development of retinal neovascularization has been very rarely reported.
Nesrine Abroug +6 more
doaj +2 more sources
MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo [PDF]
PLoS ONE, 2012 Purpose: Milk fat globule-epidermal growth factor-factor VIII (MFGE8) is necessary for diurnal outer segment phagocytosis and promotes VEGF-dependent neovascularization.
A Swaroop +52 more
core +13 more sources