Results 21 to 30 of about 399,940 (338)
Effects of nuclear factor κB expression on retinal neovascularization and apoptosis in a diabetic retinopathy rat model [PDF]
International Journal of Ophthalmology, 2015 AIM:To investigate the expression and role of nuclear factor κB (NF-κB) in diabetic retinopathy (DR) and its relationship with neovascularization and retinal cell apoptosis.METHODS: A total of 80 male Wistar rats were randomly assigned to control (4, 8 ...
Ning Jiang +3 more
doaj +2 more sources
Ocular Syphilis with Retinal and Disc Neovascularization Treated with Bevacizumab: A Case Report
Case Reports in Ophthalmology, 2023 We report the findings observed in a young woman with ocular syphilis complicated with retinal and disc neovascularization successfully treated with intravitreal bevacizumab.
Lucia Comastri +4 more
doaj +1 more source
Frontiers in Immunology, 2022 Inflammation plays a pivotal role in ischemia-induced retinal neovascularization. Targeting microglia/macrophage-based neuroinflammation presents a promising therapeutic strategy.
Xiaowei Sun +5 more
semanticscholar +1 more source
Science Advances, 2022 For patients with proliferative diabetic retinopathy (PDR) who do not respond adequately to pan-retinal laser photocoagulation (PRP) or anti–vascular endothelial growth factor (VEGF) therapies, we hypothesized that vascular cells within neovascular ...
Yaowu Qin +14 more
semanticscholar +1 more source
Frontiers in Molecular Neuroscience, 2023 Microglia are the primary resident retinal macrophages that monitor neuronal activity in real-time and facilitate angiogenesis during retinal development. In certain retinal diseases, the activated microglia promote retinal angiogenesis in hypoxia stress
Xue-Yan Fu +5 more
semanticscholar +1 more source
Journal of Clinical Investigation, 2021 Therapies targeting VEGF have proven only modestly effective for the treatment of proliferative sickle cell retinopathy (PSR), the leading cause of blindness in patients with sickle cell disease.
Jing Zhang +19 more
semanticscholar +1 more source
Case Reports in Ophthalmological Medicine, 2021 We report the rescue effect of intravitreal aflibercept injections on retinal neovascularization and macular edema due to Eales disease. Case 1 was a 36-year-old female. Intravitreal aflibercept was administered as rescue therapy after persistent retinal
Ning-Yi Hsia +6 more
doaj +1 more source
Nattokinase Attenuates Retinal Neovascularization Via Modulation of Nrf2/HO-1 and Glial Activation
Investigative Ophthalmology and Visual Science, 2021 Purpose Nattokinase (NK), an active ingredient extracted from traditional food Natto, has been studied for prevention and treatment of cardiovascular diseases due to various vasoprotective effects, including fibrinolytic, antihypertensive, anti ...
Zijing Huang +9 more
semanticscholar +1 more source
Peripheral retinal neovascularization in a patient with obstructive sleep apnea
American Journal of Ophthalmology Case Reports, 2022 Purpose: To describe a case of peripheral retinal neovascularization and its possible etiological connection to comorbid obstructive sleep apnea. Observations: In this case report we describe a diabetic patient with obstructive sleep apnea who presented ...
Ravin Sajnani +4 more
doaj +1 more source
The progress of prophylactic treatment in retinopathy of prematurity [PDF]
International Journal of Ophthalmology, 2018 Retinopathy of prematurity (ROP) is a retinal vascular disorder frequently found in premature infants. Different therapeutic strategies have been developed to treat ROP.
Hong-Bing Zhang +3 more
doaj +1 more source