Scientific Reports, 2023 Retinal pathological neovascularization involves endothelial cells, pericytes, photoreceptor cells, ganglion cells, and glial cells, whose roles remain unclear.
Lushu Chen +5 more
doaj +1 more source
Journal of Biophotonics, Volume 15, Issue 12, December 2022., 2022 In ophthalmic surgery, intraoperative retinal perfusion assessment/monitoring has been suggested for numerous indications, typically using fluorescence angiography. However, applicability is limited given the difficult arrangement, associated risks and the lack of automated/objective perfusion quantification.
Tim J. Enz +9 more
wiley +1 more source
Deletion of LRP5 in VLDLR knockout mice inhibits retinal neovascularization. [PDF]
PLoS ONE, 2013 The development and maintenance of retinal vasculature require a precise balance between pro-angiogenic and anti-angiogenic factors. However, mechanisms underlying normal homeostasis of retinal vasculature and pathological changes of disrupted retinal ...
Chun-hong Xia +3 more
doaj +1 more source
Mass spectrometry in ocular drug research
Mass Spectrometry Reviews, EarlyView., 2023 Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo +6 more
wiley +1 more source
ROCT-Net: A new ensemble deep convolutional model with improved spatial resolution learning for detecting common diseases from retinal OCT images [PDF]
, 2022 Optical coherence tomography (OCT) imaging is a well-known technology for visualizing retinal layers and helps ophthalmologists to detect possible diseases. Accurate and early diagnosis of common retinal diseases can prevent the patients from suffering critical damages to their vision.
arxiv +1 more source
Laser Doppler holography of the anterior segment for blood flow imaging, eye tracking, and transparency assessment [PDF]
, 2021 Laser Doppler holography (LDH) is a full-field blood flow imaging technique able to reveal human retinal and choroidal blood flow with high temporal resolution. We here report on using LDH in the anterior segment of the eye without making changes to the instrument.
arxiv +1 more source
NADPH oxidase, NOX1, mediates vascular injury in ischemic retinopathy [PDF]
, 2014 <b>Aims:</b> Ischemic retinal diseases such as retinopathy of prematurity are major causes of blindness due to damage to the retinal microvasculature.
Alex Agrotis +16 more
core +3 more sources
BEST1 novel mutation causes Bestrophinopathies in six families with distinct phenotypic diversity
Molecular Genetics &Genomic Medicine, Volume 11, Issue 1, January 2023., 2023 BEST1 novel mutation causes Bestrophinopathies in six families with distinct phenotypic diversity. Abstract Purpose To report novel BEST1 variants in six Chinese families with bestrophinopathies of two different inheritance modes and analyze the intrafamilial phenotypic diversity.
Shangying Yang +8 more
wiley +1 more source
Vitamin D receptor expression is essential during retinal vascular development and attenuation of neovascularization by 1, 25(OH)2D3. [PDF]
PLoS ONE, 2017 Vitamin D provides a significant benefit to human health, and its deficiency has been linked to a variety of diseases including cancer. Vitamin D exhibits anticancer effects perhaps through inhibition of angiogenesis. We previously showed that the active
Nasim Jamali +4 more
doaj +1 more source
MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo [PDF]
, 2012 Purpose: Milk fat globule-epidermal growth factor-factor VIII (MFGE8) is necessary for diurnal outer segment phagocytosis and promotes VEGF-dependent neovascularization.
A Swaroop +52 more
core +7 more sources