Results 91 to 100 of about 34,005 (206)

HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model

EBioMedicine, 2018
Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss. The protein HtrA1 is enriched in retinal pigment epithelial (RPE) cells isolated from AMD patients and in drusen deposits.
Esther Melo, Philipp Oertle, Carolyn Trepp, Hélène Meistermann, Thomas Burgoyne, Lorenzo Sborgi, Alvaro Cortes Cabrera, Chia-yi Chen, Jean-Christophe Hoflack, Tony Kam-Thong, Roland Schmucki, Laura Badi, Nicholas Flint, Zeynep Eren Ghiani, Fréderic Delobel, Corinne Stucki, Giulia Gromo, Alfred Einhaus, Benoit Hornsperger, Sabrina Golling, Juliane Siebourg-Polster, Francoise Gerber, Bernd Bohrmann, Clare Futter, Tom Dunkley, Sebastian Hiller, Oliver Schilling, Volker Enzmann, Sascha Fauser, Marija Plodinec, Roberto Iacone   +30 more
doaj   +1 more source

Retinal differentiation of human bone marrow-derived stem cells by co-culture with retinal pigment epithelium in vitro.

, 2015
The goal of this study was to assess the in vitro differentiation capacity of human bone marrow-derived stem cells (hBMSCs) along retinal lineages. Mononuclear cells (MNC) were isolated from bone marrow (BM) and mobilized peripheral blood (mPB) using ...
Baerlocher, Gabriela M., Enzmann, Volker, Brunold, Claudio, Trepp, Carolyn Mary, Mathivanan, Isai   +4 more
core   +1 more source

The cultivation of human retinal pigment epithelial cells on Bombyx mori silk fibroin

, 2012
We have presently evaluated membranes prepared from Bombyx mori silk fibroin (BMSF), for their potential use as a prosthetic Bruch's membrane and carrier substrate for human retinal pigment epithelial (RPE) cell transplantation.
Chirila, Traian V., Kwan, Anthony S., Harkin, Damien G., Shadforth, Audra, Shadforth, Audra M. A., George, Karina A., Kwan, Anthony   +6 more
core   +1 more source

The polarized expression of Na+,K+-ATPase in epithelia depends on the association between beta-subunits located in neighboring cells

, 2005
The polarized distribution of Na+,K+-ATPase plays a paramount physiological role, because either directly or through coupling with co- and countertransporters, it is responsible for the net movement of, for example, glucose, amino acids, Ca2+, K+, Cl ...
Shoshani, L, Balda, MS, Cereijido, M, Matter, K, Moreno, J, Contreras, RG, Roldan, ML, Lazaro, A   +7 more
core  

Viral vector-mediated RNA interference in the retina

, 2010
RNA interference (RNAi) is a highly conserved post-transcriptional gene silencing process triggered by double-stranded RNA (dsRNA) in eukaryotic cells.
Georgiadis, A.
core  

Biocompatibility of the vital dye Acid Violet-17 on retinal pigment epithelial cells

, 2016
Ayşegül Tura,1 Aizhan Alt,1 Julia Lüke,1 Salvatore Grisanti,1 Christos Haritoglou,2 Carsten H Meyer,3 Khaled Nassar,1 Matthias Lüke1 On behalf of the International Chromovitrectomy Collaboration 1Department of Ophthalmology, University ...
Grisanti S, Haritoglou C, Lüke J, Lüke M, Nassar K, Meyer CH, Tura A, Alt A   +7 more
core  

Ultrasound-targeted microbubble destruction enhances AAV mediated gene transfection: human RPE cells in vitro and the rat retina in vivo

, 2009
The present study was performed to investigate the efficacy and safety of Ultrasound-targeted microbubble destruction (UTMD) mediated rAAV2-EGFP to cultured human retinal pigment epithelium (RPE) cells _in vitro_ and the rat retina _in vivo_.
Xiaozhi Zheng, Huiping Wang, Ying Wu, Lianfang Du, Hongli Li, Fan Li   +5 more
core  

Fullerol in human lens and retinal pigment epithelial cells: Time domain fluorescence spectroscopyand imaging

, 2011
Fullerol in human lens and retinal pigment epithelial cells: Time domain fluorescence spectroscopyand ...
CUBEDDU, RINALDO, D'ANDREA, COSIMO, VALENTINI, GIANLUCA, Gianluca Valentini, J. E. Roberts, Cosimo D’Andrea, Joan E. Roberts, Rinaldo Cubeddu, TARONI, PAOLA, D. N. Hu, Paola Taroni, Dan-Ning Hu   +11 more
core   +1 more source

Evaluation of ultraviolet light toxicity on cultured retinal pigment epithelial and retinal ganglion cells

, 2010
Sankarathi Balaiya, Ravi K Murthy, Vikram S Brar, Kakarla V ChalamDepartment of Ophthalmology, University of Florida College of Medicine, Jacksonville, FL, USAPurpose: Our study is aimed at evaluating the role of UVB light in inducing ...
Sankarathi Balaiya, Ravi K Murthy, et al, Vikram S Brar   +3 more
core  

Retinal stem/progenitor properties of iris pigment epithelial cells

, 2006
Neural stem cells/progenitors that give rise to neurons and glia have been identified in different regions of the brain, including the embryonic retina and ciliary epithelium of the adult eye.
Sun, Guangwei, Ohta, Hiroshi, Kosaka, Jun, Kosaka, Mitsuko, Asami, Maki   +4 more
core   +1 more source