Results 71 to 80 of about 34,005 (206)

Downregulation of VEGF mRNA expression by triamcinolone acetonide acetate-loaded chitosan derivative nanoparticles in human retinal pigment epithelial cells

International Journal of Nanomedicine, 2012
Huaisheng Zhou,1 Liqun Yang,2,* Huajie Li,2 Haijun Gong,1 Liangzheng Cheng,2 Haisheng Zheng,1 Li-Ming Zhang,2 Yuqing Lan1,*1Department of Ophthalmology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, 2Institute of Polymer Science, School of ...
Zhou H, Yang L, Li H, Gong H, Cheng L, Zheng H, Zhang L, Lan Y   +7 more
doaj  

Biomaterial templates for the culture and transplantation of retinal pigment epithelial cells: A critical review

, 2016
The idea of retinal cell transplantation as a potential treatment for age-related retinal degeneration, a leading cause of blindness in the Western world, has been around for a number of decades. To date, however, it has not been entirely successful; one
F.K. Chen, Harkin, Damien G., T.V. Chirila, A.M.A. Shadforth, D.G. Harkin, Shadforth, Audra, Kwan, Anthony S.L., A.S.L. Kwan, Chen, Fred K., Chirila, Traian   +9 more
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The apical submembrane cytoskeleton participates in the organization of the apical pole in epithelial cells [PDF]

, 1997
In a previous publication (Rodriguez, M.L., M. Brignoni, and P.J.I. Salas. 1994. J. Cell Sci. 107: 3145-3151), we described the existence of a terminal web-like structure in nonbrush border cells, which comprises a specifically apical cytokeratin ...
Ana L. Viciana, Viciana, A. L., Salas, Pedro J.I, Dora E. Vega-Salas, Hauri, H. P., Hans-Peter Hauri, Marcelo L. Rodriguez, Rodriguez, M. L., Hauri, Hans-Peter, Vega-Salas, D. E., Salas, P. J., Pedro J.I. Salas, Rodriguez, Marcelo L, Vega-Salas, Dora E, Viciana, Ana L   +14 more
core   +1 more source

The role of Rab27a in the regulation of melanosome distribution within retinal pigment epithelial cells

, 2004
Melanosomes within the retinal pigment epithelium (RPE) of mammals have long been thought to exhibit no movement in response to light, unlike fish and amphibian RPE.
Seabra, MC, Futter, CE, Ramalho, JS, Jaissle, GB, Seeliger, MW   +4 more
core  

Untapping the Potential of Human Retinal Pigmented Epithelial Cells [PDF]

Cell Stem Cell, 2012
The innate capacity of adult somatic cells has many potential applications in regenerative medicine. In this issue of Cell Stem Cell, Salero et al. (2012) describe an adult retinal stem cell population capable of generating neural and mesenchymal cell lineages.
openaire   +2 more sources

A comparative study of the potential for human retinal pigment epithelium utilising an embryonic chick model of the phenomenon

, 2014
The retinal pigment epithelial (RPE) cells of several species, including: chicken, rat, mouse and newt, have been observed to undergo a phenomenon known as transdifferentiation.
Smart, MJK
core  

Progressive retinal degeneration and glial activation in the Cln6nclf mouse model of neuronal ceroid lipofuscinosis : a beneficial effect of DHA and Curcumin supplementation

, 2013
Neuronal ceroid lipofuscinosis (NCL) is a group of neurodegenerative lysosomal storage disorders characterized by vision loss, mental and motor deficits, and spontaneous seizures.
Monica Langiu, Myriam Mirza, Langiu, Monica, Tamm, Ernst R., Mirza, Myriam, Langmann, Thomas, Ernst R. Tamm, Aleksandra Somogyi, Marcus Karlstetter, Mika O. Ruonala, Volz, Cornelia, Jägle, Herbert, Herbert Jägle, Ernst R Tamm, Somogyi, Aleksandra, Cornelia Volz, Thomas Langmann, Mika O Ruonala, Karlstetter, Marcus, Ruonala, Mika O.   +19 more
core   +1 more source

Primary Cilium-Mediated Retinal Pigment Epithelium Maturation Is Disrupted in Ciliopathy Patient Cells

Cell Reports, 2018
Summary: Primary cilia are sensory organelles that protrude from the cell membrane. Defects in the primary cilium cause ciliopathy disorders, with retinal degeneration as a prominent phenotype.
Helen Louise May-Simera, Qin Wan, Balendu Shekhar Jha, Juliet Hartford, Vladimir Khristov, Roba Dejene, Justin Chang, Sarita Patnaik, Quanlong Lu, Poulomi Banerjee, Jason Silver, Christine Insinna-Kettenhofen, Dishita Patel, Mostafa Lotfi, May Malicdan, Nathan Hotaling, Arvydas Maminishkis, Rupa Sridharan, Brian Brooks, Kiyoharu Miyagishima, Meral Gunay-Aygun, Rajarshi Pal, Christopher Westlake, Sheldon Miller, Ruchi Sharma, Kapil Bharti   +25 more
doaj   +1 more source

Oxidative Stress Increases Endogenous Complement-Dependent Inflammatory and Angiogenic Responses in Retinal Pigment Epithelial Cells Independently of Exogenous Complement Sources. [PDF]

, 2019
Oxidative stress-induced damage of the retinal pigment epithelium (RPE) and chronic inflammation have been suggested as major contributors to a range of retinal diseases.
Nicole Schäfer, Schäfer, Nicole, Trakkides, Timon-Orest, Joachim Wegener, Kühn, Konstanze, Urban, Florian, Ricardo J. M. G. E. Brandwijk, Toonen, Erik J M, Florian Urban, Maria Reichenthaler, Pauly, Diana, Timon-Orest Trakkides, Reichenthaler, Maria, Enzmann, Volker, Volker Enzmann, Brandwijk, Ricardo J M G E, Wegener, Joachim, Konstanze Kühn, Diana Pauly, Erik J. M. Toonen   +19 more
core   +1 more source

DEL-1: a promising treatment for AMD-associated ER stress in retinal pigment epithelial cells

Journal of Translational Medicine
Background Age-related macular degeneration (AMD) is an irreversible eye disease that can cause blurred vision. Regular exercise has been suggested as a therapeutic strategy for treating AMD, but how exercise improves AMD is not yet understood.
ChangHyuk Kwon, Wonjun Cho, Sung Woo Choi, Heeseung Oh, A. M. Abd El-Aty, Ibrahim Gecili, Ji Hoon Jeong, Tae Woo Jung   +7 more
doaj   +1 more source