Results 61 to 70 of about 34,005 (206)

FLII and MLL1 Cooperatively Regulate Aryl Hydrocarbon Receptor-Mediated Transcription in ARPE-19 Cells

Current Issues in Molecular Biology, 2021
Aryl hydrocarbon receptors (AHRs), a class of ligand-dependent nuclear receptors that regulate cellular responses by inducing the expression of various target genes in response to external signals, are implicated in maintaining retinal tissue homeostasis.
Kwang Won Jeong
doaj   +1 more source

Regulation of thioredoxin by ceramide in retinal pigment epithelial cells [PDF]

Experimental Eye Research, 2009
The purpose of this study was to determine the expression, regulation and signaling of a key redoxin family member thioredoxin 1 (Trx1) in normal, oxidant-stimulated and growth factor-pretreated RPE cells. Trx1 is expressed in early passage, human RPE cell cultures.
Parameswaran G, Sreekumar, Yi, Ding, Stephen J, Ryan, Ram, Kannan, David R, Hinton   +4 more
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Cytokine Production by Retinal Pigmented Epithelial Cells

, 1993
Publisher Summary This chapter discusses cytokine production by retinal pigmented epithelial cells. The retinal pigmented epithelium (RPE) has many functions through which it assists the photoreceptors in visual transduction. In addition to the well-recognized day-to-day maintenance functions, the RPE also plays a very active role in normal and ...
openaire   +2 more sources

Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells

Nature Communications, 2020
Whilst pigmentation has been used to identify retinal pigment epithelial (RPE) cells, surface markers for these cells remain unclear. Here, the authors define surface markers for the RPE including CD140b, which help produce hPSC-derived RPE cells at a ...
Alvaro Plaza Reyes, Sandra Petrus-Reurer, Sara Padrell Sánchez, Pankaj Kumar, Iyadh Douagi, Hammurabi Bartuma, Monica Aronsson, Sofie Westman, Emma Lardner, Helder André, Anna Falk, Emeline F. Nandrot, Anders Kvanta, Fredrik Lanner   +13 more
doaj   +1 more source

Electrogenic sodium-bicarbonate cotransport in human ciliary muscle cells

, 1992
We investigated membrane voltage and intracellular pH (pHi) in cultured human ciliary muscle cells using a cell line (H7CM) and primary-cultured human ciliary muscle cells.
Lepple-Wienhues, A., Stahl, F., E. Tamm, M. Wiederholt, Kuppinger, M., M. Kuppinger, Tamm, Ernst R., A. Lepple-Wienhues, Wiederholt, M., F. Stahl   +9 more
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Inflammatory factors secreted from endothelial cells induced by high glucose impair human retinal pigment epithelial cells

Türk Biyokimya Dergisi
Diabetic retinopathy (DR) is a retinal disease that arises from impaired glucose tolerance and leads to retinal microvascular leakages. Recent studies have indicated that DR pathogenesis is linked to dysfunctional retinal pigment epithelial (RPE) cells.
Yao Hui, Li Tingjun, Zhang Jing
doaj   +1 more source

A Safe GDNF and GDNF/BDNF Controlled Delivery System Improves Migration in Human Retinal Pigment Epithelial Cells and Survival in Retinal Ganglion Cells: Potential Usefulness in Degenerative Retinal Pathologies

, 2021
We assessed the sustained delivery effect of poly (lactic-co-glycolic) acid (PLGA)/vitamin E (VitE) microspheres (MSs) loaded with glial cell-derived neurotrophic factor (GDNF) alone (GDNF-MSs) or combined with brain-derived neurotrophic factor (BDNF ...
Fernández Robredo, Patricia, Herrero Vanrell, María Del Rocío, Alicia Arranz-Romera, Arranz Romera, Alicia, Rocío Herrero-Vanrell, Young, Michael J., Recalde, Sergio, Hernández, Alicia, Checa Casalengua, Patricia, Molina Martínez, Irene Teresa, Irene T. Molina-Martinez, Patricia Checa-Casalengua, Checa-Casalengua, Patricia, Tucker, Budd A., Alfredo Garcia-Layana, Bravo Osuna, Irene, Maria Hernandez, Patricia Fernandez-Robredo, García-Layana, Alfredo, Michael J. Young, Sergio Recalde, Fernández-Robredo, Patricia, Irene Bravo-Osuna, Budd A. Tucker, García Layana, Alfredo, Hernandez, Maria   +25 more
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Structure and function of the retinal pigment epithelium, photoreceptors and cornea in the eye of Sardinella aurita (Clupeidae, Teleostei)

Journal of Basic and Applied Zoology, 2016
The structure of the pigment epithelium, photoreceptors and the cornea in the eye of a teleost, Sardinella aurita was examined by light and electron microscopy.
Mostafa Ali Salem
doaj   +1 more source

Mechanisms of protein aggregation in the retinal pigment epithelial cells

Frontiers in Bioscience, 2010
The pathogenesis of age-related macular degeneration (AMD) essentially involves chronic oxidative stress, increased accumulation of lipofuscin in retinal pigment epithelial (RPE) cells and extracellular drusen formation, as well as the presence of chronic inflammation. The capacity to prevent the accumulation of cellular cytotoxic protein aggregates is
Kai, Kaarniranta, Juha, Hyttinen, Tuomas, Ryhanen, Johanna, Viiri, Tuomas, Paimela, Elisa, Toropainen, Iiris, Sorri, Antero, Salminen   +7 more
openaire   +2 more sources

Purinergic and muscarinic modulation of the cell cycle and calcium signaling in the chick retinal ventricular zone

, 2002
Spontaneous calcium transients occur in the ventricular zone of the chick retina and result from the endogenous release of neurotransmitters in the absence of action potentials.
Catsicas, M., Peter Mobbs, Pearson, R., Pearson, Rachel; id_orcid, Becker, D., Pearson, R, Rachel Pearson, Becker, D, Mobbs, P, Becker, David, Marina Catsicas, Catsicas, Marina, Catsicas, M, Mobbs, Peter, David Becker, Mobbs, P.   +15 more
core   +1 more source