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The Properties of Retinal Pigment Epithelial Cells in Proliferative Vitreoretinopathy Compared with Cultured Retinal Pigment Epithelial Cells

Experimental Eye Research, 1996
Retinal pigment epithelial (RPE) cells, which proliferate and dedifferentiate under several pathological conditions, and cultured RPE cells have been considered a good model for comparison. In this investigation, we compared the properties of RPE cells in proliferative vitreoretinopathy with that of cultured human RPE cells.
T, Abe, Y K, Durlu, M, Tamai
openaire   +2 more sources

Actin-Dependent Pigment Granule Transport in Retinal Pigment Epithelial Cells

The Biological Bulletin, 1997
Since diffusion of particles as large as vesicles or organelles is constrained by the high viscosity of cytoplasm, directed translocation of these particles from one cytoplasmic site to another must be achieved by cytoskeletal intervention. In most cases, this is achieved by attaching the particle to a molecular motor which then navigates along a ...
B, Burnside, C, King-Smith
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Mechanisms Involved in Retinal Pigment Epithelial Cell Chemotaxis

Archives of Ophthalmology, 1986
Retinal pigment epithelial (RPE) cell chemotaxis may play an important role in proliferative vitreoretinopathy (PVR). Fibronectin and platelet-derived growth factor are chemoattractants for RPE cells. In this study, we used these chemoattractants to examine mechanisms involved in RPE cell chemotaxis.
P A, Campochiaro, B M, Glaser
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Rat retinal progenitor cells and a retinal pigment epithelial factor

Developmental Brain Research, 2001
Retinal progenitor cells were isolated from explants of neonatal rat retinas and characterized by transmission electron microscopy and reverse transcriptase-polymerase chain reaction and by their response to an isolated retinal pigment epithelial cell cell factor.
H J, Sheedlo   +3 more
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Phototoxicity of chlorpromazine on retinal pigment epithelial cells

Current Eye Research, 1988
As it is known that chlorpromazine (CPZ) can bind to melanins as well as cause ocular phototoxicity, we investigated the cytotoxic effects of UV-visible irradiation of melanotic and amelanotic retinal pigment epithelial (RPE) cells in the presence of CPZ.
S, Persad   +3 more
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Aldose Reductase in Human Retinal Pigment Epithelial Cells

Experimental Eye Research, 1993
Sugar alcohols have been reported to accumulate in retinal pigment epithelium (RPE) of diabetic animals. This finding has raised interest in the role of RPE in diabetes-associated retinal changes such as cystoid macular edema. To confirm the presence of aldose reductase in this tissue, the NADPH-dependent enzyme was purified to an apparent homogeneity ...
S, Sato   +3 more
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Retinal Pigment Epithelial Cells in Culture Produce Retinal Vascular Mitogens

Archives of Ophthalmology, 1988
Conditioned medium from human retinal pigment epithelial cells in culture significantly stimulated the proliferation of subcultured bovine retinal capillary endothelial cells, pericytes, and freshly isolated retinal microvessels. The vascular mitogenic activity enhanced that of retinal crude extract. No evidence emerged of an inhibitor of microvascular
H C, Wong   +5 more
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Dispersion of retinal pigment epithelial cells from experimental retinal holes

Graefe's Archive for Clinical and Experimental Ophthalmology, 1991
The effects of cryotherapy, transcleral massage, or directed irrigation on exposed retinal pigment epithelial (RPE) cells at the base of an experimental retinal hole were studied in living rabbit eyes. Cryotherapy or massage with or without vitrectomy failed to release RPE cells or result in preretinal membrane formation.
S A, Bishara, S M, Buzney
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Transplantation of Retinal Pigment Epithelial Cells

2001
Transplantations of retinal pigment epithelial (RPE) cells into the subretinal space in animal models of age-related macular degeneration (ARMD) have demonstrated that degenerative processes can be prevented, and much hope is pinned on this therapeutic approach. During the past 2 decades, intra- or subretinal transplantation of retinal cells or tissues
Monika Valtink   +3 more
openaire   +1 more source

TISSUE CULTURE OF THE RETINAL PIGMENT EPITHELIAL CELLS

Acta Ophthalmologica, 1978
Pure culture of the retinal pigment epithelial (RPE) cells of the chick embryo was carried out and the morphological characteristics of each developmental stage were observed under light microscope and transmission and scanning electron microscopes.Immature cells had a few, short processes on the apical surface and a few melanin granules in the ...
M, Hayashi, K, Asayama, S, Ueno
openaire   +2 more sources

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