Results 241 to 250 of about 54,681 (257)
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Experimental Eye Research, 2003
Cellular retinaldehyde binding protein (CRALBP) functions in the visual cycle and mutations in the RLBP1 gene can lead to blindness. RLBP1 promoter analyses have been pursued in vitro as an approach to deciphering the mechanism controlling cell-specific expression of CRALBP.
Breandán N, Kennedy +5 more
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Cellular retinaldehyde binding protein (CRALBP) functions in the visual cycle and mutations in the RLBP1 gene can lead to blindness. RLBP1 promoter analyses have been pursued in vitro as an approach to deciphering the mechanism controlling cell-specific expression of CRALBP.
Breandán N, Kennedy +5 more
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Involvement of calcium in retinal pigment epithelial cell proliferation and pigmentation
Current Eye Research, 1998The aim of this study is to explore the role of intracellular calcium in the mechanism of co-regulation of retinal pigment epithelial cells (RPE) by vitreous fluid and platelet mitogens, in order to evaluate the use of calcium modulating drugs in preventing RPE cell proliferation and contraction of fibrocellular membranes.Monolayers of human RPE cells ...
L, Smith-Thomas +9 more
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Retinal pigment epithelial cell culture
New CellObjective: Retinal pigment epithelial cells (RPEs), as the main cellular component of the preretinal membrane, whose excessive proliferation can lead to the development of proliferative vitreoretinopathy as interaction with other cellular components and intercellular substance.
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Expression of hematopoietic cell markers by retinal pigment epithelial cells
Current Eye Research, 1997We investigated the expression of various isoforms of the hematopoietic cell marker CD45 on retinal pigment epithelial cells in relation to their expression of CD68 and the cytokine-reactive intercellular adhesion molecule-1 (ICAM-1). We also determined the effect of the pro-inflammatory cytokines IL-1 beta, TNF alpha and IFN gamma on the expression of
G A, Limb +5 more
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Transplantation of Retinal Pigment Epithelial Cells
Archives of Ophthalmology, 1988A recent article in theNew York Times(Sept 25, 1988, p 13) highlighted findings on the transplantation of retinal pigment epithelial (RPE) cells as a means of "treating" retinal degeneration in the Royal College of Surgeons (RCS) rat. The article stated that this procedure not only was successful in treating retinal degeneration in this animal model ...
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Melanosome Motility in Fish Retinal Pigment Epithelial Cells
2009Several model systems have been developed to investigate intracellular organelle motility. A relatively novel system that is simple but useful for studying mechanisms of organelle motility is the fish retinal pigment epithelial (RPE) cell. Primary cultures of dissociated RPE cells are easily prepared and amenable to organelle motility studies. In vivo,
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Transdifferentiation of cultured retinal pigment epithelial cells
1998Tractional retinal detachment is a common final pathway to a number of different pathological entities, including trauma, rhegmatogenous retinal detachment and diabetic retinopathyl. Fundamentally, the various stages of this peculiar process can be characterized as wound healing or response mechanisms.
S. Grisanti, C. Guidry, K. Heimann
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Culture of retinal pigment epithelial cells from subretinal fluid
Graefe's Archive for Clinical and Experimental Ophthalmology, 1990Culture of cells from subretinal fluid (SRF) was performed using 29 SRF samples obtained at retinal reattachment surgery. Proliferating cells were found in 58.6% of the samples studied. The cells were of retinal pigment epithelial (RPE) origin, as evidenced by their brown pigmentation in primary culture and their positive immunostaining for ...
V, Sirén +4 more
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[Retinal pigment epithelial cell transplantation: perspective].
Nippon Ganka Gakkai zasshi, 1997Age-related macular degeneration is one of the most serious diseases in elderly people because of its disasterous visual outcome and its prevalence. Even if the submacular and choroidal neovascular membranes could be surgically excised, severe damage or evacuation of retinal pigment epithelium is inevitable in the operated area. Pigmentary dystrophy is
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Lysosome preparation from retinal pigment epithelial cells
Biochemical Society Transactions, 1993Bosworth, A. E. +2 more
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