Results 21 to 30 of about 30,619 (236)
Journal of Tissue Engineering, 2016 The retinal pigment epithelium is an important part of the vertebrate eye, particularly in studying the causes and possible treatment of age-related macular degeneration.
Aaron H Fronk, Elizabeth Vargis
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A defined subset of clonal retinal stem cell spheres is biased to RPE differentiation
iScience, 2021 Summary: Retinal stem cells (RSCs) are rare pigmented cells found in the pigmented ciliary layer of the mammalian retina. Studies show that RSCs can replicate to maintain the stem cell pool and produce retinal progenitors that differentiate into all ...
Tahani W. Baakdhah +2 more
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Beni-Suef University Journal of Basic and Applied Sciences, 2023 Background In the pathophysiology of the retina, the epithelial–mesenchymal transition and oxidative stress play key roles. To find a relationship between oxidative stress and diabetic retinopathy or proliferative retinopathy, we used an in-silico ...
Brijesh Gelat +5 more
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Electrical estimulation of retinal pigment epithelial cells
Experimental Eye Research, 2010 We investigated and characterized the effect of externally applied electric fields (EF) on retinal pigment epithelial (RPE) cells by exposing primary cultures of human RPE cells (hRPE) and those from the ARPE19 immortalized cell line to various strengths of EF (EF-treated cells) or to no EF (control cells) under different conditions including presence ...
Gamboa, O.L. +6 more
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eLife, 2017 Here we report multiple lines of evidence for a comprehensive model of energy metabolism in the vertebrate eye. Metabolic flux, locations of key enzymes, and our finding that glucose enters mouse and zebrafish retinas mostly through photoreceptors ...
Mark A Kanow +16 more
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Retinal Pigment Epithelial Cells Produce Fibronectin
Ophthalmic Research, 2009 Antichick fibronectin antiserum, noncross-reactive to bovine fibronectin, was prepared to determine the production of fibronectin by cultured chick retinal pigment epithelial cells which were grown in the presence of fetal bovine serum. The typical fibrillary net pattern of fibronectin was observed by an indirect immunofluorescent technique when this ...
R, Yamakawa +5 more
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Advances in the study of tissue-engineered retinal pigment epithelial cell sheets
Regenerative TherapyRegarded as the most promising treatment modality for retinal degenerative diseases, retinal pigment epithelium cell replacement therapy holds significant potential.
Wang Zhou +5 more
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Molecules, 2022 Diabetic retinopathy (DR) is a neurovascular disease characterized by the reduction of retina integrity and functionality, as a consequence of retinal pigment epithelial cell fibrosis.
Maria Consiglia Trotta +8 more
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Cross-talk between microRNA-let7c and transforming growth factor-β2 during epithelial-to-mesenchymal transition of retinal pigment epithelial cells [PDF]
International Journal of Ophthalmology, 2020 AIM: To explore the roles of microRNA-let7c (miR-let7c) and transforming growth factor-β2 (TGF-β2) and cellular signaling during epithelial-to-mesenchymal transition (EMT) of retinal pigment epithelial cells. METHODS: Retinal pigment epithelial (ARPE-19)
Qu-Zhen Deji +5 more
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Stem Cell Reports, 2017 Summary: Antibody-mediated rejection is characterized by donor-specific antibody produced by B cells. However, to our knowledge, B cell invasion and antibody in the inflamed retina after transplantation of retinal pigment epithelial (RPE) cells has not ...
Sunao Sugita +7 more
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