Results 151 to 160 of about 91,639 (372)

Advances in the study of tissue-engineered retinal pigment epithelial cell sheets

open access: yesRegenerative Therapy
Regarded as the most promising treatment modality for retinal degenerative diseases, retinal pigment epithelium cell replacement therapy holds significant potential.
Wang Zhou   +5 more
doaj  

Retinal findings in membranoproliferative glomerulonephritis

open access: yesAmerican Journal of Ophthalmology Case Reports, 2017
Purpose: To assess the evolution of retinal findings in patients with membranoproliferative glomerulonephritis (MPGN) by funduscopy, intravenous fluorescein angiography and optical coherence tomography. Observations: Three women and one man were followed
Ahmad M. Mansour   +6 more
doaj   +1 more source

Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate. [PDF]

open access: yes, 2017
The light absorbing chromophore in opsin visual pigments is the protonated Schiff base of 11-cis-retinaldehyde (11cRAL). Absorption of a photon isomerizes 11cRAL to all-trans-retinaldehyde (atRAL), briefly activating the pigment before it dissociates ...
Fain, Gordon L   +6 more
core   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz   +9 more
wiley   +1 more source

Bacterial cellulose as a support for the growth of retinal pigment epithelium.

open access: yesBiomacromolecules, 2015
The feasibility of bacterial cellulose (BC) as a novel substrate for retinal pigment epithelium (RPE) culture was evaluated. Thin (41.6 ± 2.2 μm of average thickness) and heat-dried BC substrates were surface-modified via acetylation and polysaccharide ...
S. Gonçalves   +8 more
semanticscholar   +1 more source

JAPANESE QUAIL (COTURNIX JAPONICA) AS THE MODEL OF HUMAN AGING RETINAL PROCESSES. REPORT № 2. COMPARATIVE ANALYSIS OF THE COMPOSITION OF RETINOIDS ISOLATED FROM RETINAL PIGMENT EPITHELIUM OF HUMAN AND JAPANESE QUAIL EYES

open access: yesОфтальмохирургия, 2015
Purpose. To compare the composition of retinoids of lipofuscin granules (LG) isolated from retinal pigment epithelium (RPE) of human cadaver eyes and Japanese quail. Material and methods.
M. A. Yakovleva   +6 more
doaj  

Chemokine-mediated inflammation in the degenerating retina is coordinated by Müller cells, activated microglia, and retinal pigment epithelium

open access: yesJournal of Neuroinflammation, 2015
BackgroundMonocyte infiltration is involved in the pathogenesis of many retinal degenerative conditions. This process traditionally depends on local expression of chemokines, though the roles of many of these in the degenerating retina are unclear. Here,
Matt Rutar   +4 more
semanticscholar   +1 more source

Epinephrine, but not dexamethasone, induces apoptosis in human retinal pigment epithelium cells in vitro: Possible implications on the pathogenesis of central serous chorioretinopathy

open access: yesPhilippine Journal of Ophthalmology, 2004
Objective: The pathogenesis of central serous chorioretinopathy is poorly understood. It is believed to be due to dysfunction of the retinal pigment epithelium and/or choroid, and has been associated with elevated levels of epinephrine and administration
Santiago Antonio B. Sibayan, MD, PhD   +6 more
doaj  

A Deep Learning Approach to Digitally Stain Optical Coherence Tomography Images of the Optic Nerve Head [PDF]

open access: yesarXiv, 2017
Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1 eye of each of 100 subjects (40 normal & 60 glaucoma). All images were enhanced using adaptive compensation.
arxiv  

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