Spectral tuning and deactivation kinetics of marine mammal melanopsins.
PLoS ONE, 2021 In mammals, the photopigment melanopsin (Opn4) is found in a subset of retinal ganglion cells that serve light detection for circadian photoentrainment and pupil constriction (i.e., mydriasis).
Jeffry I Fasick +6 more
doaj +2 more sources
Diacylglycerol O-acyltransferase type-1 synthesizes retinyl esters in the retina and retinal pigment epithelium. [PDF]
PLoS ONE, 2015 Retinyl esters represent an insoluble storage form of vitamin A and are substrates for the retinoid isomerase (Rpe65) in cells of the retinal pigment epithelium (RPE).
Joanna J Kaylor +9 more
doaj +1 more source
A two-step method for identifying photopigment opsin and rhodopsin gene sequences underlying human color vision phenotypes. [PDF]
, 2020 PurposeTo present a detailed, reliable long range-PCR and sequencing (LR-PCR-Seq) procedure to identify human opsin gene sequences for variations in the long wavelength-sensitive (OPN1LW), medium wavelength-sensitive (OPN1MW), short wavelength-sensitive (
Atilano, Shari R +3 more
core +1 more source
Photoreceptor Outer Segment-like Structures in Long-Term 3D Retinas from Human Pluripotent Stem Cells. [PDF]
, 2017 The retinal degenerative diseases, which together constitute a leading cause of hereditary blindness worldwide, are largely untreatable. Development of reliable methods to culture complex retinal tissues from human pluripotent stem cells (hPSCs) could ...
Angueyra, Juan M +9 more
core +1 more source
Early evolution of purple retinal pigments on Earth and implications for exoplanet biosignatures
, 2018 We propose that retinal-based phototrophy arose early in the evolution of life on Earth, profoundly impacting the development of photosynthesis and creating implications for the search for life beyond our planet.
DasSarma, Shiladitya +1 more
core +1 more source
RETINAL SPARING BY SELECTIVE RETINAL PIGMENT EPITHELIAL PHOTOCOAGULATION [PDF]
Evidence-Based Eye Care, 1999 To investigate whether photocoagulation of the retinal pigment epithelium is possible with sparing of the photoreceptors.Mild laser effects of a neodymium:yttrium-lithium-fluoride (Nd:YLF) laser (527 nm) were applied to 17 patients. To establish the necessary energy, test exposures were performed to the lower macula (laser variables: 1.7 microseconds ...
J, Roider +4 more
openaire +2 more sources
Retinitis Pigmentosa with Congenital Sensorineural Hearing Loss: Ushers Syndrome
BLDE University Journal of Health Sciences, 2020 Background: Retinitis pigmentosa or pigmentary retinal dystrophy denotes a clinically and genetically diverse group of inherited diffuse retinal degenerative diseases.
M H Patil, Piyushi Sao
doaj +1 more source
Evolution of the eyes of vipers with and without infrared-sensing pit organs [PDF]
, 2019 We examined lens and brille transmittance, photoreceptors, visual pigments, and visual opsin gene sequences of viperid snakes with and without infrared-sensing pit organs. Ocular media transmittance is high in both groups.
Douglas, R. H. +12 more
core +3 more sources
Retinal Pigment Epithelium Lipofuscin Proteomics [PDF]
Molecular & Cellular Proteomics, 2008 Lipofuscin accumulates with age in the retinal pigment epithelium (RPE) in discrete granular organelles and may contribute to age-related macular degeneration. Because previous studies suggest that lipofuscin contains protein that may impact pathogenic mechanisms, we pursued proteomics analysis of lipofuscin.
Kwok-Peng, Ng +14 more
openaire +2 more sources
Serpentine retinal pigment epithelial tear
Taiwan Journal of Ophthalmology, 2021 We report a case of retinal pigment epithelial tear in a patient with peripheral exudative hemorrhagic chorioretinopathy (PEHCR). A 60-year-old diabetic female presented with left eye metamorphopsia. Fundus examination showed bilateral peripheral retinal pigment epithelium (RPE) degeneration, and a large serpentine-shaped RPE ...
Aditya Maitray +2 more
openaire +3 more sources