Results 101 to 110 of about 24,391 (241)

Generation of a Double Reporter mES Cell Line to Simultaneously Trace the Generation of Retinal Progenitors and Photoreceptors

Cells
Three-dimensional retinal culture systems help to understand eye development and the pathology of disorders. There is a need for reporter stem cell lines to allow in vitro studies on retinal progenitors and photoreceptors and their developmental dynamics
Oleksandr Zabiegalov, Adeline Berger, Dhryata Kamdar, Kabirou Adamou, Chuanxi Tian, Martial Mbefo, Mathieu Quinodoz, Florian Udry, Carlo Rivolta, Corinne Kostic, Yvan Arsenijevic   +10 more
doaj   +1 more source

Localisation of NG2 immunoreactive neuroglia cells in the rat locus coeruleus and their plasticity in response to stress [PDF]

, 2014
The locus coeruleus (LC) nucleus modulates adaptive behavioural responses to stress and dysregulation of LC neuronal activity is implicated in stress-induced mental illnesses.
Metzger, Friedrich, Friedrich Metzger, Metzger, F, Seifi, Mohsen, Mohsen eSeifi, Johannes J. van der Want, Corteen, Nicole L, Jerome D Swinny, van der Want, Johannes J, Corteen, Nicole L., Seifi, M, Swinny, Jerome D, Corteen, NL, Johannes Jacobus Van Der Want, Nicole L. Corteen, Swinny, Jerome D., Swinny, JD, van der Want, Johannes J., van der Want, Johannes, Nicole Louise Corteen, Mohsen Seifi, Jerome D. Swinny, Friedrich eMetzger   +22 more
core   +1 more source

A multipotent transit-amplifying neuroblast lineage in the central brain gives rise to optic lobe glial cells in Drosophila [PDF]

, 2013
The neurons and glial cells of the Drosophila brain are generated by neural stem cell-like progenitors during two developmental phases, one short embryonic phase and one more prolonged postembryonic phase.
Reichert, Heinrich, Viktorin, Gudrun, Riebli, Nadia   +2 more
core   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

Interphotoreceptor matrix-poly(ϵ-caprolactone) composite scaffolds for human photoreceptor differentiation

Journal of Tissue Engineering, 2014
Tissue engineering has been widely applied in different areas of regenerative medicine, including retinal regeneration. Typically, artificial biopolymers require additional surface modification (e.g. with arginine–glycine–aspartate-containing peptides or
Petr Baranov, Andrew Michaelson, Joydip Kundu, Rebecca L Carrier, Michael Young   +4 more
doaj   +1 more source

Induction of rod versus cone photoreceptor-specific progenitors from retinal precursor cells

Stem Cell Research, 2018
During development, multipotent progenitors undergo temporally-restricted differentiation into post-mitotic retinal cells; however, the mechanisms of progenitor division that occurs during retinogenesis remain controversial.
Saeed Khalili, Brian G. Ballios, Justin Belair-Hickey, Laura Donaldson, Jeff Liu, Brenda L.K. Coles, Kenneth N. Grisé, Tahani Baakdhah, Gary D. Bader, Valerie A. Wallace, Gilbert Bernier, Molly S. Shoichet, Derek van der Kooy   +12 more
doaj   +1 more source

A comparative study of the potential for human retinal pigment epithelium utilising an embryonic chick model of the phenomenon

, 2014
The retinal pigment epithelial (RPE) cells of several species, including: chicken, rat, mouse and newt, have been observed to undergo a phenomenon known as transdifferentiation.
Smart, MJK
core  

Biogenesis of TNF‐α‐insights into proteostasis and inflammation

The FEBS Journal, EarlyView.
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar, Céline Philippe, Eric Chevet, Jiří Zahradník   +3 more
wiley   +1 more source

Genomic analysis of mouse retinal development.

PLoS Biology, 2004
The vertebrate retina is comprised of seven major cell types that are generated in overlapping but well-defined intervals. To identify genes that might regulate retinal development, gene expression in the developing retina was profiled at multiple time ...
Seth Blackshaw, Sanjiv Harpavat, Jeff Trimarchi, Li Cai, Haiyan Huang, Winston P Kuo, Griffin Weber, Kyungjoon Lee, Rebecca E Fraioli, Seo-Hee Cho, Rachel Yung, Elizabeth Asch, Lucila Ohno-Machado, Wing H Wong, Constance L Cepko   +14 more
doaj   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source