Results 121 to 130 of about 5,449,684 (261)

Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis. [PDF]

Stem Cell Res Ther, 2022
Jin C, Ou Q, Chen J, Wang T, Zhang J, Wang Z, Wang Y, Tian H, Xu JY, Gao F, Wang J, Li J, Lu L, Xu GT.   +13 more
europepmc   +1 more source

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

Phytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia, Kaiyi Wu, Jiaying Qi, Nana Huang, Yusheng Liu, Xiumei Gao, Rong Sun   +6 more
wiley   +1 more source

mTORC1 accelerates retinal development via the immunoproteasome

Nature Communications, 2018
One of the determinants of the neuronal subtype produced from retinal progenitor cells is their proliferative potential. Here the authors show that mTORC1 promotes progenitor cell cycle progression and hence accelerated development in mouse retina ...
Ji-Heon Choi, Hong Seok Jo, Soyeon Lim, Hyoung-Tai Kim, Kang Woo Lee, Kyeong Hwan Moon, Taejeong Ha, Sang Soo Kwak, Yeha Kim, Eun Jung Lee, Cheol O. Joe, Jin Woo Kim   +11 more
doaj   +1 more source

Top2b regulates morphological and migratory properties of retinal progenitor cells in vivo and upon transplantable matrix substrates [PDF]

Exploration of BioMat-X
Aim: This study evaluated the impact of retinal extracellular matrix (ECM) and key biomaterial substrates on the motility of transplantable retinal cells with genomic manipulation, using the therapeutic molecule, Topoisomerase II beta (Top2b), as a model.
Alexandra C. Dabrowski, Alexandria R. Logan, Rameshwari Rayaji, Brianna Rodriguez, Li Cai, Maribel Vazquez   +5 more
doaj   +1 more source

Biocompatibility of Human Induced Pluripotent Stem Cell-Derived Retinal Progenitor Cell Grafts in Immunocompromised Rats. [PDF]

Cell Transplant, 2022
Han IC, Bohrer LR, Gibson-Corley KN, Wiley LA, Shrestha A, Harman BE, Jiao C, Sohn EH, Wendland R, Allen BN, Worthington KS, Mullins RF, Stone EM, Tucker BA.   +13 more
europepmc   +1 more source

Radial outer retina reflectivity (RORR) sign in LAMP2‐associated retinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the radial outer retina reflectivity (RORR) sign in patients carrying pathogenic variants in the X‐linked lysosome‐associated membrane protein‐2 (LAMP2) gene and to review the histologic characteristics of LAMP2 expression in the human retina.
Rachael C. Heath Jeffery, Bohdan Kousal, Ulrike Grünert, Christine A. Curcio, Svetlana Cherepanoff, Tina M. Lamey, Michel Michaelides, Chrysanthi Tsika, Isabelle Chow, Omar A. Mahroo, Seungmin Lee, Martin Meliska, Milos Kubanek, Jakub Sikora, Siying Lin, Raymond C. B. Wong, Petra Liskova, Fred K. Chen   +17 more
wiley   +1 more source

Differentiation of Mesenchymal Stem Cells into Retinal Progenitor Cells [PDF]

Ophthalmic Research, 2014
Gustavo Sevlever, Santiago Miriuka, Fernando Pitossi   +2 more
openaire   +2 more sources

Dataset for "Label-free enrichment of human pluripotent stem cell-derived early retinal progenitor cells for cell-based regenerative therapies"

<p>The raw dataset for "Label-free enrichment of human pluripotent stem cell-derived early retinal progenitor cells for cell-based regenerative therapies"</p> <p><span>DOI:</span><a href="https://doi.org/10.1016/j.stemcr ...
Nomaru, Hiroko, Teranishi, Kazuki, Masuda, Tomohiro, Iwama, Yasuaki, Murata, Yuri, Nishida, Kohji, Mandai, Michiko, Matsumura, Michiru, Kawamura, Yoko, Ota, Sadao, Takahashi, Masayo   +10 more
core   +1 more source

mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia. [PDF]

Elife, 2021
Lim S, Kim YJ, Park S, Choi JH, Sung YH, Nishimori K, Kozmik Z, Lee HW, Kim JW.   +8 more
europepmc   +1 more source

PABPC1 in Cancer: From a Translational Housekeeper to a Stress‐Responsive Regulatory Hub

Cancer Science, EarlyView.
PABPC1 shifts from a translational housekeeper to a stress‐responsive oncogenic hub via phase separation, PTMs, and non‐coding RNA crosstalk, selectively driving oncogene translation and therapy resistance in cancer. ABSTRACT PABPC1, long recognized as a constitutive translational housekeeper, has emerged as a stress‐responsive translational ...
Cuiwei Zhang, Ye Zhu, Wenbo Long
wiley   +1 more source