Adult limbal neurosphere cells: a potential autologous cell resource for retinal cell generation. [PDF]
PLoS ONE, 2014 The Corneal limbus is a readily accessible region at the front of the eye, separating the cornea and sclera. Neural colonies (neurospheres) can be generated from adult corneal limbus in vitro.
Xiaoli Chen +5 more
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Enhanced generation of retinal progenitor cells from human retinal pigment epithelial cells induced by amniotic fluid [PDF]
BMC Research Notes, 2012 Background Retinal progenitor cells are a convenient source of cell replacement therapy in retinal degenerative disorders. The purpose of this study was to evaluate the expression patterns of the homeobox genes PAX6 and CHX10 (retinal progenitor markers)
Sanie-Jahromi Fatemeh +9 more
doaj +2 more sources
Characterization of Progenitor Cells during Canine Retinal Development [PDF]
Stem Cells International, 2012 We identify the presence of progenitor cells during retinal development in the dog, as this species represents a natural model for studying several breed-specific degenerative retinal disorders.
Mallely Ávila-García +3 more
doaj +3 more sources
Evidence for a retinal progenitor cell in the postnatal and adult mouse
Stem Cell Research, 2017 Progress in cell therapy for retinal disorders has been challenging. Recognized retinal progenitors are a heterogeneous population of cells that lack surface markers for the isolation of live cells for clinical implementation. In the present application,
Xi Chen +10 more
doaj +3 more sources
SURGICAL RETINAL EXPLANTS AS A SOURCE OF RETINAL PROGENITOR CELLS. [PDF]
Retina, 2021 Purpose: To describe the novel observation of spontaneously migrating retinal cells from living donor surgical retinal explants that express progenitor cell markers in the absence of exogenous growth factors. Methods: Surgical retinal explants were harvested from 5 consecutive ...
Too LK +5 more
europepmc +4 more sources
Cell Fate of Retinal Progenitor Cells: In Ovo UbC-StarTrack Analysis. [PDF]
Int J Mol Sci, 2022 Clonal cell analysis outlines the ontogenic potential of single progenitor cells, allowing the elucidation of the neural heterogeneity among different cell types and their lineages. In this work, we analyze the potency of retinal stem/progenitor cells through development using the chick embryo as a model.
Olmos-Carreño CL +3 more
europepmc +5 more sources
Bone marrow derived cells as endothelial precursors and the role of multi-potent progenitor cells in repairing ischaemic tissues. [PDF]
, 2007 PhDIntroduction: Atherosclerosis and its complications are a major cause of death and disability and it remains a major challenge to develop new therapies for patients with irreversible end organ damage and ongoing ischaemia.
Wragg, Andrew
core +4 more sources
Scientific Reports, 2021 Notch signaling is required to repress the formation of vertebrate cone photoreceptors and to maintain the proliferative potential of multipotent retinal progenitor cells.
Xueqing Chen, Mark M. Emerson
doaj +1 more source
Influence of hypoxia on retinal progenitor and ganglion cells in human induced pluripotent stem cell-derived retinal organoids [PDF]
International Journal of Ophthalmology, 2023 AIM: To observe the effect of low oxygen concentration on the neural retina in human induced pluripotent stem cell (hiPSC)-derived retinal organoids (ROs). METHODS: The hiPSC and a three-dimensional culture method were used for the experiments. Generated
Jin-Lin Du +9 more
doaj +1 more source
Morphological asymmetry in dividing retinal progenitor cells [PDF]
Development, Growth & Differentiation, 2003 For the understanding of histogenetic events in the 3‐D retinal neuroepithelium, direct observation of the progenitor cells and their morphological changes is required. A slice culture method has been developed by which the behavior of single progenitor cells can be monitored.
Kanako, Saito +5 more
openaire +2 more sources