Results 11 to 20 of about 24,696 (239)
Retinal progenitor cells (jCell) for retinitis pigmentosa [PDF]
Frontiers in Cellular NeuroscienceObjectiveTo assess the safety and tolerability of intravitreal injection of human retinal progenitor cells (RPCs) at multiple dose levels in adults with non-syndromic retinitis pigmentosa (RP).DesignA prospective, multicenter, open-label, single-arm ...
Jing Yang +11 more
doaj +5 more sources
Characterization of Progenitor Cells during Canine Retinal Development [PDF]
Stem Cells International, 2012 We identify the presence of progenitor cells during retinal development in the dog, as this species represents a natural model for studying several breed-specific degenerative retinal disorders.
Mallely Ávila-García +3 more
doaj +4 more sources
Activation of c-Jun N-terminal kinase (JNK) during mitosis in retinal progenitor cells. [PDF]
PLoS ONE, 2012 Most studies of c-Jun N-terminal Kinase (JNK) activation in retinal tissue were done in the context of neurodegeneration. In this study, we investigated the behavior of JNK during mitosis of progenitor cells in the retina of newborn rats.
Vinicius Toledo Ribas +3 more
doaj +2 more sources
In Vitro Isolation and Expansion of Human Retinal Progenitor Cells [PDF]
Experimental Neurology, 2002 Human retinal development proceeds with temporal and spatial precision. Although differentiation starts around the beginning of the third month of gestation, the majority of cells in the outer neuroblastic layer of human neural retina are still ...
Seiler, Magdalene J +3 more
core +6 more sources
Efficacy and Safety of Human Retinal Progenitor Cells. [PDF]
Translational Vision Science & Technology, 2016 PURPOSE: We assessed the long-term efficacy and safety of human retinal progenitor cells (hRPC) using established rodent models. METHODS: Efficacy of hRPC was tested initially in Royal College of Surgeons (RCS) dystrophic rats immunosuppressed with ...
Coffey, P +9 more
core +4 more sources
Developmental Biology, 2007 Retinal progenitor cells are believed to display altered proliferation and differentiation during retinal development, suggesting that retinal progenitor cell populations are not homogeneous. However, the composition of progenitor cell populations is not
Hideto Koso +2 more
exaly +2 more sources
Retinal stem/progenitor properties of iris pigment epithelial cells
Developmental Biology, 2006 Neural stem cells/progenitors that give rise to neurons and glia have been identified in different regions of the brain, including the embryonic retina and ciliary epithelium of the adult eye.
Maki Asami +2 more
exaly +2 more sources
Evidence for a retinal progenitor cell in the postnatal and adult mouse
Stem Cell Research, 2017 Progress in cell therapy for retinal disorders has been challenging. Recognized retinal progenitors are a heterogeneous population of cells that lack surface markers for the isolation of live cells for clinical implementation. In the present application,
Xi Chen +10 more
doaj +3 more sources
SURGICAL RETINAL EXPLANTS AS A SOURCE OF RETINAL PROGENITOR CELLS. [PDF]
Retina, 2021 Purpose: To describe the novel observation of spontaneously migrating retinal cells from living donor surgical retinal explants that express progenitor cell markers in the absence of exogenous growth factors. Methods: Surgical retinal explants were harvested from 5 consecutive ...
Too LK +5 more
europepmc +4 more sources
Characterizing and influencing differentiation of Retinal Progenitor Cells
, 2007 Blinding degenerative retinal diseases including retinitis pigmentosa, macular degeneration and glaucoma are characterized by loss of retinal neurons. At this time there is no way to replace retinal cell loss due to disease or injury since differentiated
Dunn-Thomas, Tyra
core +3 more sources