Results 31 to 40 of about 48,023 (234)

Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1

Cell Reports, 2023
Summary: Transitions in competence underlie the ability of CNS progenitors to generate a diversity of neurons and glia. Retinal progenitor cells in mouse generate early-born cell types embryonically and late-born cell types largely postnatally.
Jianmin Zhang, Jacqueline M. Roberts, Fei Chang, Joon Schwakopf, Monica L. Vetter   +4 more
doaj   +1 more source

The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation. [PDF]

, 2017
Low-grade gliomas are one of the most common brain tumors in children, where they frequently form within the optic pathway (optic pathway gliomas; OPGs).
Castillon, Guillaume A, Cimino, Patrick J, Ellisman, Mark H, Gianino, Scott M, Gutmann, David H, Lee, Da Yong, Ma, Yu, Pan, Yuan, Solga, Anne C, Toonen, Joseph A   +9 more
core   +3 more sources

Regulating Retinoic Acid Availability during Development and Regeneration: The Role of the CYP26 Enzymes. [PDF]

, 2020
This review focuses on the role of the Cytochrome p450 subfamily 26 (CYP26) retinoic acid (RA) degrading enzymes during development and regeneration. Cyp26 enzymes, along with retinoic acid synthesising enzymes, are absolutely required for RA homeostasis
Roberts, C
core   +2 more sources

OTX2 represses sister cell fate choices in the developing retina to promote photoreceptor specification

eLife, 2020
During vertebrate retinal development, subsets of progenitor cells generate progeny in a non-stochastic manner, suggesting that these decisions are tightly regulated.
Miruna Georgiana Ghinia Tegla, Diego F Buenaventura, Diana Y Kim, Cassandra Thakurdin, Kevin C Gonzalez, Mark M Emerson   +5 more
doaj   +1 more source

Docosahexaenoic acid promotes photoreceptor differentiation without altering Crx expression [PDF]

, 2006
PURPOSE: The precise molecular cues required for photoreceptor development are still unknown. Pax6 and Crx are essential during early retinal development and for photoreceptor differentiation, respectively.
Garelli, Andres, Politi, Luis Enrique, Rotstein, Nora Patricia   +2 more
core   +2 more sources

Nel positively regulates the genesis of retinal ganglion cells by promoting their differentiation and survival during development [PDF]

, 2014
Peer reviewedPublisher ...
Adams JC, Agathocleous M, Aihara K, Amy S. Findlay, Austin CP, Cayouette M, Cepko CL, Chizu Nakamoto, de Iongh R, Ehrlich D, Elaine Durward, Ewa D. Zakrzewska, Fekete DM, Flanagan JG, Frade JM, Galvez JM, Hansen MJ, Harada H, Harpavat S, Hashimoto T, Holt CE, Hu WY, Isenmann S, Jablonski MM, Jablonski MM, Jiang Y, Jiang Y, Katahira T, Koga A, Kuroda S, Layer PG, Marianne Bronner, Martinez-Morales JR, Masai I, Masaru Nakamoto, Matsuhashi S, Matsuhashi S, Matsuoka H, Matsuyama S, Matsuyama S, McCabe KL, McCabe KL, McLaughlin T, Moore SW, Munemasa Y, Nakamura R, Nelson BR, Nelson BR, Oyasu M, Patel A, Prada C, Price J, Rachel RA, Raymond SM, Sato Y, Snow RL, Soh-Leh Kuan, Stiemke MM, Strauss O, Takuma Endo, Wang JT, Watanabe TK, Wetts R, Xiang M, Yee JK, Zhang XM, Zhang XM, Zhufeng Ouyang   +67 more
core   +1 more source

Enhanced generation of retinal progenitor cells from human retinal pigment epithelial cells induced by amniotic fluid

BMC Research Notes, 2012
Background Retinal progenitor cells are a convenient source of cell replacement therapy in retinal degenerative disorders. The purpose of this study was to evaluate the expression patterns of the homeobox genes PAX6 and CHX10 (retinal progenitor markers)
Sanie-Jahromi Fatemeh, Ahmadieh Hamid, Soheili Zahra-Soheila, Davari Maliheh, Ghaderi Shima, Kanavi Mozhgan, Samiei Shahram, Deezagi Abdolkhalegh, Pakravesh Jalil, Bagheri Abouzar   +9 more
doaj   +1 more source

Molecular Characterization of Human Retinal Progenitor Cells

Investigative Opthalmology & Visual Science, 2009
To examine the molecular profile of fetal human retinal progenitor cells (hRPCs) expanded in vitro and those grown in a co-culture system with mouse retina through the analysis of protein and gene expression and neurotransmitter-stimulated calcium dynamics.hRPCS were isolated from human retina of 14 to 18 weeks gestational age (GA) and expanded in ...
Scott, Schmitt, Unber, Aftab, Caihui, Jiang, Stephen, Redenti, Henry, Klassen, Erik, Miljan, John, Sinden, Michael, Young   +7 more
openaire   +2 more sources

Adult limbal neurosphere cells: a potential autologous cell resource for retinal cell generation.

PLoS ONE, 2014
The Corneal limbus is a readily accessible region at the front of the eye, separating the cornea and sclera. Neural colonies (neurospheres) can be generated from adult corneal limbus in vitro.
Xiaoli Chen, Heather Thomson, Jessica Cooke, Jennifer Scott, Parwez Hossain, Andrew Lotery   +5 more
doaj   +1 more source

Extracellular vesicles from organoid-derived human retinal progenitor cells prevent lipid overload-induced retinal pigment epithelium injury by regulating fatty acid metabolism. [PDF]

J Extracell Vesicles
Gao H, Zeng Y, Huang X, A L, Liang Q, Xie J, Lin X, Gong J, Fan X, Zou T, Xu H.   +10 more
europepmc   +2 more sources