Results 21 to 30 of about 24,696 (239)
Cell Fate of Retinal Progenitor Cells: In Ovo UbC-StarTrack Analysis. [PDF]
Int J Mol Sci, 2022 Clonal cell analysis outlines the ontogenic potential of single progenitor cells, allowing the elucidation of the neural heterogeneity among different cell types and their lineages. In this work, we analyze the potency of retinal stem/progenitor cells through development using the chick embryo as a model.
Olmos-Carreño CL +3 more
europepmc +5 more sources
miR-762 regulates the proliferation and differentiation of retinal progenitor cells by targeting NPDC1. [PDF]
Cell Cycle, 2020 Gao H +10 more
europepmc +2 more sources
Cells, 2021 Regenerative medicine in ophthalmology that uses induced pluripotent stem cells (iPS) cells has been described, but those studies used iPS cells derived from fibroblasts.
Naoki Yamamoto +11 more
doaj +1 more source
Scientific Reports, 2021 Notch signaling is required to repress the formation of vertebrate cone photoreceptors and to maintain the proliferative potential of multipotent retinal progenitor cells.
Xueqing Chen, Mark M. Emerson
doaj +1 more source
Influence of hypoxia on retinal progenitor and ganglion cells in human induced pluripotent stem cell-derived retinal organoids [PDF]
International Journal of Ophthalmology, 2023 AIM: To observe the effect of low oxygen concentration on the neural retina in human induced pluripotent stem cell (hiPSC)-derived retinal organoids (ROs). METHODS: The hiPSC and a three-dimensional culture method were used for the experiments. Generated
Jin-Lin Du +9 more
doaj +1 more source
Intravitreal Injection of Human Retinal Progenitor Cells for Treatment of Retinal Degeneration. [PDF]
Med Sci Monit, 2020 BACKGROUND Retinal degeneration causes irreversible blindness. Human retinal progenitor cells (hRPCs) have the potential to treat retinal diseases. The vitreous cavity is a relatively immune-privileged site that is suitable for stem cell transplantation in the treatment of retinal diseases.
Wang Z +7 more
europepmc +4 more sources
Morphological asymmetry in dividing retinal progenitor cells [PDF]
Development, Growth & Differentiation, 2003 For the understanding of histogenetic events in the 3‐D retinal neuroepithelium, direct observation of the progenitor cells and their morphological changes is required. A slice culture method has been developed by which the behavior of single progenitor cells can be monitored.
Kanako, Saito +5 more
openaire +2 more sources
A microfabricated scaffold for retinal progenitor cell grafting [PDF]
Biomaterials, 2008 Diseases that cause photoreceptor cell degeneration afflict millions of people, yet no restorative treatment exists for these blinding disorders. Replacement of photoreceptors using retinal progenitor cells (RPCs) represents a promising therapy for the treatment of retinal degeneration.
William L, Neeley +6 more
openaire +2 more sources
Stem Cell Research & Therapy, 2021 Objective Retinal degenerative diseases remain the dominant causes of blindness worldwide, and cell replacement is viewed as a promising therapeutic direction. However, the resources of seed cells are hard to obtain.
Yifeng Ke +8 more
doaj +1 more source
Dual requirement for Pax6 in retinal progenitor cells [PDF]
Development, 2008 Throughout the developing central nervous system, pre-patterning of the ventricular zone into discrete neural progenitor domains is one of the predominant strategies used to produce neuronal diversity in a spatially coordinated manner. In the retina, neurogenesis proceeds in an intricate chronological and spatial sequence, yet it remains unclear ...
Oron-Karni, Varda +8 more
openaire +3 more sources