Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing. [PDF]
Li J +19 more
europepmc +1 more source
Multifunctional Hydrogels: Rational Design and Application in Regenerative Medicine
Multifunctional hydrogels represent a paradigm shift in regenerative medicine, integrating rational material design with bioactive functionality to address complex tissue repair challenges. This review systematically examines the molecular engineering, structure–function relationships, and translational landscape of advanced hydrogel systems, spanning ...
Linyang Song +4 more
wiley +1 more source
Genetic ablation of the TET family in retinal progenitor cells impairs photoreceptor development and leads to blindness. [PDF]
Dvoriantchikova G +6 more
europepmc +1 more source
Human Retinal Progenitor Cells Derived Small Extracellular Vesicles Delay Retinal Degeneration: A Paradigm for Cell-free Therapy. [PDF]
Chen M +9 more
europepmc +1 more source
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider +3 more
wiley +1 more source
Amelioration of Photoreceptor Degeneration by Intravitreal Transplantation of Retinal Progenitor Cells in Rats. [PDF]
Yang J +8 more
europepmc +1 more source
Human primitive mesenchymal stem cell-derived retinal progenitor cells improved neuroprotection, neurogenesis, and vision in rd12 mouse model of retinitis pigmentosa. [PDF]
Brown C +7 more
europepmc +1 more source
Abstract As crewed space missions set course for the Moon and beyond, astronauts will experience prolonged exposure to Galactic Cosmic Rays (GCR) and potentially intense Solar Proton Events (SPEs), both of which pose significant short‐ and long‐term health risks.
Sylvain Blunier +4 more
wiley +1 more source
A lithium‐free temperature‐controlled shipping system (YOTI) stabilizes physiologic temperatures during overnight transport of mature human iPSC‐derived retinal organoids. Compared to conventional ambient shipping, YOTI reduces temperature fluctuations, preserves retinal lamination, decreases cell death, and maintains rod photoreceptor marker ...
Karen Cusato +7 more
wiley +1 more source
PHLDA1-PRDM1 mediates the effect of lentiviral vectors on fate-determination of human retinal progenitor cells. [PDF]
Hu X +7 more
europepmc +1 more source

