During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu +5 more
wiley +1 more source
Conditional Immortalization Using SV40 Large T Antigen and Its Effects on Induced Pluripotent Stem Cell Differentiation Toward Retinal Progenitor Cells. [PDF]
Wang Q +5 more
europepmc +1 more source
Construction and characterization of EGFP reporter plasmid harboring putative human RAX promoter for in vitro monitoring of retinal progenitor cells identity. [PDF]
Atefi A +4 more
europepmc +1 more source
Rethinking the Oligodendrocyte Progenitor Cell: One Cell, Many Functions
Oligodendrocyte progenitor cells (OPCs) are increasingly recognised as multifunctional CNS cells rather than mere precursors of myelinating oligodendrocytes. Alongside myelination and remyelination, they contribute to myelin and circuit plasticity, circuit regulation, vascular and blood–brain barrier regulation and neuroimmune modulation.
Alerie G. de la Fuente
wiley +1 more source
Neural cell phenotypes were tested using cells derived from two pairs of siblings strongly discordant for reading—probands with severe RD and their strong‐reader siblings. We observed significant differences in outgrowth in the neurosphere assay using the neural precursor cells (NPCs) derived from the probands compared to cells from their strong‐reader
Cathy L. Barr +12 more
wiley +1 more source
[Effects of leptin on proliferation and differentiation of hypoxic rat retinal progenitor cells in vitro]. [PDF]
Xing Y, Liu Z, Zhang X, Wang J.
europepmc +1 more source
Abstract figure legend Maternal protein restriction (MPR) induced persistent renal histopathological alterations accompanied by elevated serum creatinine levels. Nephron‐segment proteomic analysis revealed region‐specific molecular dysregulation affecting Bowman's capsule (PARK7, oxidative stress sensor; MSN, cytoskeletal organization), the proximal ...
Marina Pereira Pires +15 more
wiley +1 more source
Sstr2 Defines the Cone Differentiation-Competent Late-Stage Retinal Progenitor Cells in the Developing Mouse Retina. [PDF]
Bai Y +6 more
europepmc +1 more source
Label-free enrichment of human pluripotent stem cell-derived early retinal progenitor cells for cell-based regenerative therapies. [PDF]
Iwama Y +10 more
europepmc +1 more source

