Results 201 to 210 of about 24,696 (239)
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Rat retinal progenitor cells and a retinal pigment epithelial factor
Developmental Brain Research, 2001Retinal progenitor cells were isolated from explants of neonatal rat retinas and characterized by transmission electron microscopy and reverse transcriptase-polymerase chain reaction and by their response to an isolated retinal pigment epithelial cell cell factor.
H J, Sheedlo +3 more
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Growth kinetics and transplantation of human retinal progenitor cells
Experimental Eye Research, 2009We studied the growth kinetics of human retinal progenitor cells (hRPCs) isolated from donor tissue of different gestational ages (G.A.), determined whether hRPCs can be differentiated into mature photoreceptors and assessed their ability to integrate with degenerating host retina upon transplantation.
Caihui Jiang +2 more
exaly +3 more sources
Membrane properties of retinal stem cells/progenitors
Progress in Retinal and Eye Research, 2005The membrane properties of cells help integrate extrinsic information relayed through growth factors, chemokines, extracellular matrix, gap junctions and neurotransmitters towards modulating cell-intrinsic properties, which in turn determine whether cells remain quiescent, proliferate, differentiate, establish contact with other cells or remove ...
Ani V, Das +5 more
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Microscopic characterization of rat retinal progenitor cells
Brain Research, 2007A progenitor cell line was developed from a postnatal day 2 (P2) rat retina to study the effects of secreted proteins of the retinal pigment epithelium (RPE) on isolated retinal progenitor cells and markers for immature and differentiated retinal cells. Progenitor cells were cloned from a P2 explant grown in secreted proteins of cultured RPE cells.
Harold J, Sheedlo +3 more
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Retinal Progenitor Cells — Timing Is Everything
New England Journal of Medicine, 2007Permitting progenitor photoreceptor cells from donors to differentiate before transplanting them is key to their successful integration into the retina.
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Muller glia induce retinal progenitor cells to differentiate into retinal ganglion cells
NeuroReport, 2006Retinal progenitor cells could differentiate into various retinal cells that made cell-replacement therapy possible. Here, we investigated the role of cellular microenvironment on their regulation and differentiation and found that the percentage of proliferating cells and the percentage of retinal ganglion cells produced from them increased, when ...
Jing, Yao +3 more
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Cytotherapy, 2011
Retinal progenitor cells (RPC) are an excellent resource for retinal replacement therapy but usually unavailable. We attempted to induce bone marrow mesenchymal stromal cells (BMSC) into RPC.BMSC and embryonic day 13.5 (E13.5) RPC derived from wild-type or enhanced green fluorescence protein (EGFP) transgenic (Egfp(+/+)) mice were co-cultured in a ...
Xuerong, Sun +9 more
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Retinal progenitor cells (RPC) are an excellent resource for retinal replacement therapy but usually unavailable. We attempted to induce bone marrow mesenchymal stromal cells (BMSC) into RPC.BMSC and embryonic day 13.5 (E13.5) RPC derived from wild-type or enhanced green fluorescence protein (EGFP) transgenic (Egfp(+/+)) mice were co-cultured in a ...
Xuerong, Sun +9 more
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Influence of a retinal pigment epithelial cell factor(s) on rat retinal progenitor cells
Developmental Brain Research, 1996Retinal development was studied by explant culture of retinas from embryonic and neonatal rats in response to medium conditioned (CM) by a transformed neonatal rat retinal pigment epithelial (tnrRPE) cell line. Retinal explants from embryonic days 16 and 18 and postnatal day 2 Long-Evans rats were cultured for over 3 weeks on a poly-D,L-ornithine ...
H J, Sheedlo, J E, Turner
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Cell-intrinsic regulators of proliferation in vertebrate retinal progenitors
Seminars in Cell & Developmental Biology, 2004The proliferative expansion of retinal progenitor cells (RPCs) is a fundamental mechanism of growth during vertebrate retinal development. Over the past couple of years, significant progress has been made in identifying genes expressed in RPCs that are essential for their proliferation, and the molecular mechanisms are beginning to be resolved. In this
Edward M, Levine, Eric S, Green
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Retinal Progenitor Cells, Differentiation, and Barriers to Cell Cycle Reentry
2010Neurogenesis in the retina occurs via the coordination of proliferation, cell cycle exit and differentiation of retinal progenitor cells. Until recently, it was widely assumed that once a retinal progenitor cell produced a postmitotic neuron, there was no possibility for cell-cycle re-entry. However, recent studies have shown that mature differentiated
Denise M, Davis, Michael A, Dyer
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