Results 201 to 210 of about 23,592 (236)

Growth kinetics and transplantation of human retinal progenitor cells

Experimental Eye Research, 2009
We studied the growth kinetics of human retinal progenitor cells (hRPCs) isolated from donor tissue of different gestational ages (G.A.), determined whether hRPCs can be differentiated into mature photoreceptors and assessed their ability to integrate with degenerating host retina upon transplantation.
Unber, Aftab, Caihui, Jiang, Budd, Tucker, Ji Yeon, Kim, Henry, Klassen, Erik, Miljan, John, Sinden, Michael, Young   +7 more
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Progenitor cells and retinal angiogenesis

Angiogenesis, 2007
Nothing more dramatically captures the imagination of the visually impaired patient or the ophthalmologist treating them than the possibility of rebuilding a damaged retina or vasculature with "stem cells." Stem cells (SC) have been isolated from adult tissues and represent a pool of cells that may serve to facilitate rescue/repair of damaged tissue ...
Martin, Friedlander, Michael I, Dorrell, Matthew R, Ritter, Valentina, Marchetti, Stacey K, Moreno, Mohammad, El-Kalay, Alan C, Bird, Eyal, Banin, Edith, Aguilar   +8 more
openaire   +2 more sources

Membrane properties of retinal stem cells/progenitors

Progress in Retinal and Eye Research, 2005
The membrane properties of cells help integrate extrinsic information relayed through growth factors, chemokines, extracellular matrix, gap junctions and neurotransmitters towards modulating cell-intrinsic properties, which in turn determine whether cells remain quiescent, proliferate, differentiate, establish contact with other cells or remove ...
Ani V, Das, Sreekumaran, Edakkot, Wallace B, Thoreson, Jackson, James, Sumitra, Bhattacharya, Iqbal, Ahmad   +5 more
openaire   +2 more sources

Microscopic characterization of rat retinal progenitor cells

Brain Research, 2007
A progenitor cell line was developed from a postnatal day 2 (P2) rat retina to study the effects of secreted proteins of the retinal pigment epithelium (RPE) on isolated retinal progenitor cells and markers for immature and differentiated retinal cells. Progenitor cells were cloned from a P2 explant grown in secreted proteins of cultured RPE cells.
Harold J, Sheedlo, Allison, Heath, Anne-Marie, Brun, Neeraj, Agarwal   +3 more
openaire   +2 more sources

Expression of olig2 in retinal progenitor cells

NeuroReport, 2006
Olig2 is a basic helix-loop-helix transcription factor that is specifically expressed in oligodendrocyte precursors in the central nervous system. Owing to the absence of oligodendrocytes in the retina, however, the role of olig2 in retinal development remains unclear.
Kazuaki, Nakamura, Chikako, Harada, Kazuhiko, Namekata, Takayuki, Harada   +3 more
openaire   +2 more sources

Rat retinal progenitor cells and a retinal pigment epithelial factor

Developmental Brain Research, 2001
Retinal progenitor cells were isolated from explants of neonatal rat retinas and characterized by transmission electron microscopy and reverse transcriptase-polymerase chain reaction and by their response to an isolated retinal pigment epithelial cell cell factor.
H J, Sheedlo, A M, Brun-Zinkernagel, L X, Oakford, R S, Roque   +3 more
openaire   +2 more sources

Muller glia induce retinal progenitor cells to differentiate into retinal ganglion cells

NeuroReport, 2006
Retinal progenitor cells could differentiate into various retinal cells that made cell-replacement therapy possible. Here, we investigated the role of cellular microenvironment on their regulation and differentiation and found that the percentage of proliferating cells and the percentage of retinal ganglion cells produced from them increased, when ...
Jing, Yao, Xinghuai, Sun, Yang, Wang, Ling, Wang   +3 more
openaire   +2 more sources

E13.5 retinal progenitors induce mouse bone marrow mesenchymal stromal cells to differentiate into retinal progenitor-like cells

Cytotherapy, 2011
Retinal progenitor cells (RPC) are an excellent resource for retinal replacement therapy but usually unavailable. We attempted to induce bone marrow mesenchymal stromal cells (BMSC) into RPC.BMSC and embryonic day 13.5 (E13.5) RPC derived from wild-type or enhanced green fluorescence protein (EGFP) transgenic (Egfp(+/+)) mice were co-cultured in a ...
Xuerong, Sun, Mengfei, Chen, Juan, Li, Jing, Zhuang, Qianying, Gao, Xiufeng, Zhong, Bing, Huang, Weizhong, Zhang, Li, Huang, Jian, Ge   +9 more
openaire   +2 more sources

Glutamate regulates retinal progenitors cells proliferation during development

European Journal of Neuroscience, 2006
AbstractThe precise coordination of cell cycle exit and cell fate specification is essential for generating the correct proportion of retinal cell types during development. The decision to exit the cell cycle is regulated by intrinsic and extrinsic cues.
Rodrigo A P, Martins, Rafael, Linden, Michael A, Dyer   +2 more
openaire   +2 more sources

Decellularized retinal matrix: Natural platforms for human retinal progenitor cell culture

Acta Biomaterialia, 2016
Tissue decellularization strategies have enabled engineering of scaffolds that preserve native extracellular matrix (ECM) structure and composition. In this study, we developed decellularized retina (decell-retina) thin films. We hypothesized that these films, mimicking the retina niche, would promote human retinal progenitor cell (hRPC) attachment ...
Joydip, Kundu, Andrew, Michaelson, Kristen, Talbot, Petr, Baranov, Michael J, Young, Rebecca L, Carrier   +5 more
openaire   +2 more sources