Results 231 to 240 of about 4,562,862 (262)

Effects of retinal pigment epithelial cell‐secreted factors on neonatal rat retinal explant progenitor cells

Journal of Neuroscience Research, 1996
This study demonstrates the effects of conditioned media from transformed neonatal rat retinal pigment epithelial cells (tnrRPE-CM) in a culture system consisting of neonatal rat retinal explants. For this study, retinal explants from postnatal day 2 (PN2) normal rats were cultured for over 3 weeks on a poly-D-L-ornithine-coated surface in RPE-CM only,
H J, Sheedlo, J E, Turner
openaire   +2 more sources

Loss of retinal progenitor cells leads to an increase in the retinal stem cell population in vivo

European Journal of Neuroscience, 2005
AbstractRetinal stem cells [with the potential to produce either neural retinal progenitors or retinal pigment epithelial (RPE) progenitors] exist in the mammalian eye throughout life, and indeed the greatest absolute increase in the stem population occurs postnatally.
Brenda L K, Coles, D Jonathan, Horsford, Roderick R, McInnes, Derek, van der Kooy   +3 more
openaire   +2 more sources

Progenitor Cell Transplantation for Retinal Disease

2008
Diseases of the retina frequently result in permanent visual impairment. One strategy for recovering lost function is to replace retinal neurons lost to the disease process, while another is to protect these neurons from dying in the first place. Retinal progenitor cell transplantation is an experimental approach that has relevance to both strategies ...
openaire   +1 more source

Characterization of early retinal progenitor microenvironment: Presence of activities selective for the differentiation of retinal ganglion cells and maintenance of progenitors

Experimental Eye Research, 2007
The maintenance and differentiation of retinal progenitors take place in the context of the microenvironment in which they reside at a given time during retinal histogenesis. To understand the nature of the microenvironment in the developing retina, we have examined the influence of activities present during the early stage of retinal histogenesis on ...
Ganapati V, Hegde, Jackson, James, Ani V, Das, Xing, Zhao, Sumitra, Bhattacharya, Iqbal, Ahmad   +5 more
openaire   +2 more sources

A Comparison of Neural Differentiation and Retinal Transplantation with Bone Marrow‐Derived Cells and Retinal Progenitor Cells

STEM CELLS, 2006
Retinal progenitor cells (RPCs) are immature precursors that can differentiate into retinal neurons, including photoreceptors. Recently, it has been reported that bone marrow-derived cells may also be capable of differentiation into cells of central nervous system lineage, including retinal neurons.
Minoru, Tomita, Taisuke, Mori, Kazuichi, Maruyama, Tasneem, Zahir, Matthew, Ward, Akihiro, Umezawa, Michael J, Young   +6 more
openaire   +2 more sources

Epigenetic regulation in the commitment of progenitor cells during retinal development and regeneration

Differentiation, 2023
Songtao Yuan, Qinghuai Liu, Miao Xu
exaly  

Bio-inspired chiral self-assemblies promoted neuronal differentiation of retinal progenitor cells through activation of metabolic pathway

Bioactive Materials, 2021
Xiao-Qiu Dou, Chuan-Liang Feng, Ping Gu
exaly  

Neuroprotection by Endothelial Progenitor Cells for Retinal Degeneration

2014
Retinitis pigmentosa is an inherited eye disorder that leads to profound vision loss and is characterized by retinal neuron degeneration, fundus pigment changes, optic disc atrophy, and vasculature attenuation. Endothelial progenitor cells (EPCs), which contribute to angiogenesis, are categorized into two subpopulations according to their aldehyde ...
openaire   +1 more source

Retinal progenitor cells for treatment of retinitis pigmentosa

Journal of Clinical & Experimental Ophthalmology, 2016
openaire   +1 more source

Retinal progenitor cell therapy for retinal degeneration

Science-Business eXchange, 2014
openaire   +1 more source