Results 211 to 220 of about 24,696 (239)
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Decellularized retinal matrix: Natural platforms for human retinal progenitor cell culture
Acta Biomaterialia, 2016Tissue decellularization strategies have enabled engineering of scaffolds that preserve native extracellular matrix (ECM) structure and composition. In this study, we developed decellularized retina (decell-retina) thin films. We hypothesized that these films, mimicking the retina niche, would promote human retinal progenitor cell (hRPC) attachment ...
Joydip, Kundu +5 more
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Journal of Neuroscience Research, 1996
This study demonstrates the effects of conditioned media from transformed neonatal rat retinal pigment epithelial cells (tnrRPE-CM) in a culture system consisting of neonatal rat retinal explants. For this study, retinal explants from postnatal day 2 (PN2) normal rats were cultured for over 3 weeks on a poly-D-L-ornithine-coated surface in RPE-CM only,
H J, Sheedlo, J E, Turner
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This study demonstrates the effects of conditioned media from transformed neonatal rat retinal pigment epithelial cells (tnrRPE-CM) in a culture system consisting of neonatal rat retinal explants. For this study, retinal explants from postnatal day 2 (PN2) normal rats were cultured for over 3 weeks on a poly-D-L-ornithine-coated surface in RPE-CM only,
H J, Sheedlo, J E, Turner
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Experimental Eye Research, 2007
The maintenance and differentiation of retinal progenitors take place in the context of the microenvironment in which they reside at a given time during retinal histogenesis. To understand the nature of the microenvironment in the developing retina, we have examined the influence of activities present during the early stage of retinal histogenesis on ...
Ganapati V, Hegde +5 more
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The maintenance and differentiation of retinal progenitors take place in the context of the microenvironment in which they reside at a given time during retinal histogenesis. To understand the nature of the microenvironment in the developing retina, we have examined the influence of activities present during the early stage of retinal histogenesis on ...
Ganapati V, Hegde +5 more
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Loss of retinal progenitor cells leads to an increase in the retinal stem cell population in vivo
European Journal of Neuroscience, 2005AbstractRetinal stem cells [with the potential to produce either neural retinal progenitors or retinal pigment epithelial (RPE) progenitors] exist in the mammalian eye throughout life, and indeed the greatest absolute increase in the stem population occurs postnatally.
Brenda L K, Coles +3 more
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STEM CELLS, 2006
Retinal progenitor cells (RPCs) are immature precursors that can differentiate into retinal neurons, including photoreceptors. Recently, it has been reported that bone marrow-derived cells may also be capable of differentiation into cells of central nervous system lineage, including retinal neurons.
Minoru, Tomita +6 more
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Retinal progenitor cells (RPCs) are immature precursors that can differentiate into retinal neurons, including photoreceptors. Recently, it has been reported that bone marrow-derived cells may also be capable of differentiation into cells of central nervous system lineage, including retinal neurons.
Minoru, Tomita +6 more
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Progenitor Cell Transplantation for Retinal Disease
2008Diseases of the retina frequently result in permanent visual impairment. One strategy for recovering lost function is to replace retinal neurons lost to the disease process, while another is to protect these neurons from dying in the first place. Retinal progenitor cell transplantation is an experimental approach that has relevance to both strategies ...
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Transformation of Progenitor Cells for Treatment of Retinal Disease
2012There has been a growing interest in regenerative medicine strategies for the treatment of degenerative diseases of the retina. This chapter examines the transformation of retinal progenitors and bone marrow-derived progenitors for the treatment of retinal disease.
Jeffrey R. Harris +3 more
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Neuroprotection by Endothelial Progenitor Cells for Retinal Degeneration
2014Retinitis pigmentosa is an inherited eye disorder that leads to profound vision loss and is characterized by retinal neuron degeneration, fundus pigment changes, optic disc atrophy, and vasculature attenuation. Endothelial progenitor cells (EPCs), which contribute to angiogenesis, are categorized into two subpopulations according to their aldehyde ...
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Retinal progenitor cells for treatment of retinitis pigmentosa
Journal of Clinical & Experimental Ophthalmology, 2016openaire +1 more source