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Influence of a retinal pigment epithelial cell factor(s) on rat retinal progenitor cells
Developmental Brain Research, 1996Retinal development was studied by explant culture of retinas from embryonic and neonatal rats in response to medium conditioned (CM) by a transformed neonatal rat retinal pigment epithelial (tnrRPE) cell line. Retinal explants from embryonic days 16 and 18 and postnatal day 2 Long-Evans rats were cultured for over 3 weeks on a poly-D,L-ornithine ...
H J, Sheedlo, J E, Turner
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Journal of Neuroscience Research, 1996
This study demonstrates the effects of conditioned media from transformed neonatal rat retinal pigment epithelial cells (tnrRPE-CM) in a culture system consisting of neonatal rat retinal explants. For this study, retinal explants from postnatal day 2 (PN2) normal rats were cultured for over 3 weeks on a poly-D-L-ornithine-coated surface in RPE-CM only,
H J, Sheedlo, J E, Turner
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This study demonstrates the effects of conditioned media from transformed neonatal rat retinal pigment epithelial cells (tnrRPE-CM) in a culture system consisting of neonatal rat retinal explants. For this study, retinal explants from postnatal day 2 (PN2) normal rats were cultured for over 3 weeks on a poly-D-L-ornithine-coated surface in RPE-CM only,
H J, Sheedlo, J E, Turner
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Cell-intrinsic regulators of proliferation in vertebrate retinal progenitors
Seminars in Cell & Developmental Biology, 2004The proliferative expansion of retinal progenitor cells (RPCs) is a fundamental mechanism of growth during vertebrate retinal development. Over the past couple of years, significant progress has been made in identifying genes expressed in RPCs that are essential for their proliferation, and the molecular mechanisms are beginning to be resolved. In this
Edward M, Levine, Eric S, Green
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Retinal Progenitor Cells, Differentiation, and Barriers to Cell Cycle Reentry
2010Neurogenesis in the retina occurs via the coordination of proliferation, cell cycle exit and differentiation of retinal progenitor cells. Until recently, it was widely assumed that once a retinal progenitor cell produced a postmitotic neuron, there was no possibility for cell-cycle re-entry. However, recent studies have shown that mature differentiated
Denise M, Davis, Michael A, Dyer
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Progenitor Cell Transplantation for Retinal Disease
2008Diseases of the retina frequently result in permanent visual impairment. One strategy for recovering lost function is to replace retinal neurons lost to the disease process, while another is to protect these neurons from dying in the first place. Retinal progenitor cell transplantation is an experimental approach that has relevance to both strategies ...
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Towards Stem/Progenitor Cell-Based Therapies for Retinal Degeneration
Stem Cell Reviews and ReportsRetinal degeneration (RD) is a leading cause of blindness worldwide and includes conditions such as retinitis pigmentosa (RP), age-related macular degeneration (AMD), and Stargardt's disease (STGD). These diseases result in the permanent loss of vision due to the progressive and irreversible degeneration of retinal cells, including photoreceptors (PR ...
Hui Liu +11 more
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Retinal progenitor cell therapy for retinal degeneration
Science-Business eXchange, 2014openaire +1 more source
Retinal progenitor cells for treatment of retinitis pigmentosa
Journal of Clinical & Experimental Ophthalmology, 2016openaire +1 more source
Purification and characterization of human neural stem and progenitor cells
Cell, 2023Rahul Sinha +2 more
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