Results 21 to 30 of about 614,351 (314)

P-aminobenzoic acid promotes retinal regeneration through activation of Ascl1a in zebrafish [PDF]

Neural Regeneration Research
The retina of zebrafish can regenerate completely after injury. Multiple studies have demonstrated that metabolic alterations occur during retinal damage; however to date no study has identified a link between metabolites and retinal regeneration of ...
Meihui He, Mingfang Xia, Qian Yang, Xingyi Chen, Haibo Li, Xiaobo Xia   +5 more
doaj   +2 more sources

Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration [PDF]

Front Cell Dev Biol, 2018
Thousands of genes have been implicated in retinal regeneration, but only a few have been shown to impact the regenerative capacity of Müller glia—an adult retinal stem cell with untapped therapeutic potential.
Arife Unal Eroglu, Lisha Xu, Jeff S. Mumm, Timothy S. Mulligan, Wuhong Pei, Sumitra Sengupta, Cathy Nie, Liyun Zhang, Jiang Qian, Noela Y. Lu, Meera T. Saxena, Shawn M. Burgess, David T. White   +12 more
core   +2 more sources

From BEST1 mutations to retinal regeneration: integrating stem cell–derived RPE models and gene correction strategies [PDF]

Front Cell Dev Biol
Yan Wang, Sihua Cheng, Yifan Zhang, Tingting Yang   +3 more
openalex   +2 more sources

Understanding retinal regeneration: Core mechanisms and biological insights

Retinal regeneration is a complex, evolutionarily constrained process, resulting in the restoration of retinal structure and function upon injury. This capacity varies widely across species.
Rens Hoekstra, Ivar Noordstra, Sakurako Kobayashi, Jeroen Bakkers, Ronald Roepman, Erwin van Wijk   +5 more
openalex   +2 more sources

Novel developments in retinal regeneration: Advances and future outlooks in stem cell therapy [PDF]

World J Stem Cells
Marco Zeppieri, Federico Visalli, Mutali Musa, Alessandro Avitabile, Rosa Giglio, Daniele Tognetto, Caterina Gagliano, Fabiana D’Esposito, F. Cappellani   +8 more
openalex   +2 more sources

Three‐dimensional tissue engineering and organoid technologies for retinal regeneration and therapy [PDF]

Bioeng Transl Med
Yiqi Wang, Douglas Jiang, Qinglong Wang, Yun Cao, Hong Guo, Yi Lu, Feng Tian   +6 more
openalex   +2 more sources

The Rapid Activation of MYDGF Is Critical for Cell Survival in the Acute Phase of Retinal Regeneration in Fish [PDF]

Int J Mol Sci
Kayo Sugitani, Yuya Omori, Takumi Mokuya, Serika Hosoi, Haruto Kobayashi, Koki Miyata, Yuhei Araiso, Yoshiki Koriyama   +7 more
openalex   +2 more sources

Heavy Metal-Induced Retinal Injury in Zebrafish (Danio rerio): Histopathological Alterations, Molecular Mechanisms and Regenerative Responses [PDF]

Toxics
Alina Iliuța Olărița, Alexandra Szilágyi, Alexandra Jităreanu, Gheorghe Solcan, Carmen Solcan   +4 more
openalex   +2 more sources

Postsynaptic neuronal activity promotes regeneration of retinal axons [PDF]

, 2023
Summary: The wiring of visual circuits requires that retinal neurons functionally connect to specific brain targets, a process that involves activity-dependent signaling between retinal axons and their postsynaptic targets.
Varadarajan, Supraja G, Wang, Fei, Le, Phung, Huberman, Andrew D, Fei Wang, Phung Le, Andrew D. Huberman, Supraja G. Varadarajan, Onkar S. Dhande, Dhande, Onkar S, Xin Duan, Duan, Xin   +11 more
core   +1 more source

Robotic search for optimal cell culture in regenerative medicine

eLife, 2022
Induced differentiation is one of the most experience- and skill-dependent experimental processes in regenerative medicine, and establishing optimal conditions often takes years.
Genki N Kanda, Taku Tsuzuki, Motoki Terada, Noriko Sakai, Naohiro Motozawa, Tomohiro Masuda, Mitsuhiro Nishida, Chihaya T Watanabe, Tatsuki Higashi, Shuhei A Horiguchi, Taku Kudo, Motohisa Kamei, Genshiro A Sunagawa, Kenji Matsukuma, Takeshi Sakurada, Yosuke Ozawa, Masayo Takahashi, Koichi Takahashi, Tohru Natsume   +18 more
doaj   +1 more source