Results 11 to 20 of about 57,195 (184)
CD171- and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing [PDF]
BMC Cancer, 2019 Background Chimeric antigen receptor (CAR)-based T cell therapy is in early clinical trials to target the neuroectodermal tumor, neuroblastoma. No preclinical or clinical efficacy data are available for retinoblastoma to date.
Lena Andersch +15 more
doaj +4 more sources
Asia-Pacific Journal of Oncology Nursing, 2017 From 7% to 10% of all retinoblastomas and from 44% to 71% of familial retinoblastomas in developed countries are diagnosed in the neonatal period, usually through pre- or post-natal screening prompted by a positive family history and sometimes ...
Tero T Kivelä, Theodora Hadjistilianou
doaj +6 more sources
Revista chilena de pediatría, 1979 Retinoblastoma is a radiosensitive malignancy of neuroblastic origin that primarily affects young children. Its relatively low incidence belies its potential importance in the understanding of tumor biology in general. A case is made for referral of all retinoblastoma patients to centers with retinoblastoma protocols.
Marchevsky, Silvia +4 more
openaire +5 more sources
BMJ Open Ophthalmology, 2021 Objective To explore living with heritable retinoblastoma, specifically survivors’ perceived role of regular follow-up at a retinoblastoma survivorship clinic.Methods and analysis Adult survivors of heritable retinoblastoma were recruited from the ...
Stina Lou +7 more
doaj +1 more source
Incidence and geographic distribution of retinoblastoma in Ethiopia
BMC Ophthalmology, 2023 Introduction Retinoblastoma is the most frequent intraocular malignancy of the eye in children, occurring in early childhood. Based on global estimates, Ethiopia is expected to observe over 200 new retinoblastoma cases per year, however without a cancer ...
Sadik Taju Sherief +7 more
doaj +1 more source
Orphanet Journal of Rare Diseases, 2006 Retinoblastoma is a rare eye tumor of childhood that arises in the retina. It is the most common intraocular malignancy of infancy and childhood; with an incidence of 1/15,000-20,000 live births. The two most frequent symptoms revealing retinoblastoma are leukocoria and strabismus.
Laurence Desjardins +5 more
openaire +4 more sources
Nature Reviews Disease Primers, 2015 Retinoblastoma is a rare cancer of the infant retina that is diagnosed in approximately 8,000 children each year worldwide. It forms when both retinoblastoma gene (RB1) alleles are mutated in a susceptible retinal cell, probably a cone photoreceptor precursor.
Dimaras, Helen +10 more
openaire +5 more sources
Cell Death and Disease, 2021 Retinoblastoma is a childhood retinal tumour that is the most common primary malignant intraocular tumour. However, it has been challenging to identify the cell types associated with genetic complexity. Here, we performed single-cell RNA sequencing on 14,
Jie Yang +9 more
doaj +1 more source
Lag time, high-risk histopathological features, metastasis, and survival interrelation in retinoblastoma: a perspective from lower-middle income country [PDF]
International Journal of Ophthalmology, 2022 AIM: To investigate the impact of lag time to metastasis and survival rates among patients with retinoblastoma. METHODS: This retrospective study was conducted with 52 patients from the Department of Ophthalmology and the Department of Pediatrics of Dr ...
Purjanto Tepo Utomo +8 more
doaj +1 more source
Ophthalmology and Therapy, 2020 Plain Language Summary Through living with conditions and/or engaging with health and social care services patients, public and service users become experts by experience.
Andrew M. Skilton +2 more
doaj +1 more source