Results 11 to 20 of about 68,477 (247)
Ophthalmology and Therapy, 2020 Plain Language Summary Through living with conditions and/or engaging with health and social care services patients, public and service users become experts by experience.
Andrew M. Skilton +2 more
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Lag time, high-risk histopathological features, metastasis, and survival interrelation in retinoblastoma: a perspective from lower-middle income country [PDF]
International Journal of Ophthalmology, 2022 AIM: To investigate the impact of lag time to metastasis and survival rates among patients with retinoblastoma. METHODS: This retrospective study was conducted with 52 patients from the Department of Ophthalmology and the Department of Pediatrics of Dr ...
Purjanto Tepo Utomo +8 more
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Indian Journal of Ophthalmology, 2023 Retinoblastoma is a retinal cancer that affects children and is the most prevalent intraocular tumor worldwide. Despite tremendous breakthroughs in our understanding of the fundamental mechanisms that regulate progression of retinoblastoma, the ...
Shruti Rathore +8 more
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Bone metastasis of retinoblastoma five years after primary treatment
American Journal of Ophthalmology Case Reports, 2020 Purpose: Histopathological, immunohistochemistry- and molecular pathology-based diagnostics to distinguish metastasis of retinoblastoma from subsequent primary malignancy in patients with heritable retinoblastoma.
Saskia C. Ting +7 more
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Pharmacology Research & Perspectives, 2022 We and others have shown that aberrant activation of the mammalian target of rapamycin (mTOR) signalling is essential for retinoblastoma progression and has potential therapeutic value.
Lanlan Tang +5 more
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Longer Lag Time in Early-Stage Retinoblastoma
Folia Medica Indonesiana, 2022 Highlights: • Patients with IRSS I stage have the longest lag time than IVB stage. • Lag time is no significant with stage retinoblastoma. Abstract: Retinoblastoma is a rare neoplasm disease that occurs in children, generally under the age of ...
Anindya Citra +2 more
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Orphanet Journal of Rare Diseases, 2006 Retinoblastoma is a rare eye tumor of childhood that arises in the retina. It is the most common intraocular malignancy of infancy and childhood; with an incidence of 1/15,000-20,000 live births. The two most frequent symptoms revealing retinoblastoma are leukocoria and strabismus.
Aerts Isabelle +5 more
openaire +3 more sources
Retinoblastoma in Late Childhood
Journal of Nepal Medical Association, 2003 Retinoblastoma, the commonest intra-ocular tumor of childhood, is rare after the age of 5 years. We report a case of retinoblastoma in a 10 year-old boy, who presented with a fungating proptosed tender mass involving the entire left eye and the orbit.
B Badhu, S P Sah, S Kumar, R P Sah
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Update on pathology of retinoblastoma [PDF]
International Journal of Ophthalmology, 2018 Retinoblastoma is caused by mutational inactivation of both alleles of the RB1 gene, which maps to chromosome 13q14 and encodes retinoblastoma protein that acts as a tumor suppressor.
Lata Singh, Seema Kashyap
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Analysis of MDM2 and MDM4 single nucleotide polymorphisms, mRNA splicing and protein expression in retinoblastoma. [PDF]
PLoS ONE, 2012 Retinoblastoma is a childhood cancer of the developing retina that begins in utero and is diagnosed in the first years of life. Biallelic RB1 gene inactivation is the initiating genetic lesion in retinoblastoma.
Justina McEvoy +6 more
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