Chronic ethanol administration enhances retinoic acid and triiodothyronine receptor expression in mouse liver [PDF]
Véronique Pallet +5 more
openalex +1 more source
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Phase 1 safety, tolerability, pharmacokinetics and pharmacodynamic results of KCL‐286, a novel retinoic acid receptor‐β agonist for treatment of spinal cord injury, in male healthy participants [PDF]
Maria B. Goncalves +10 more
openalex +1 more source
The role of retinoic acid receptor-related orphan receptors in skeletal diseases. [PDF]
Zhang Y, Ma J, Bao X, Hu M, Wei X.
europepmc +1 more source
Somatic cell reprogramming for Parkinson's disease treatment
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Graves’ ophthalmopathy: low-dose dexamethasone reduces retinoic acid receptor-alpha gene expression in orbital fibroblasts [PDF]
Sarah Santiloni Cury +9 more
openalex +1 more source
ABSTRACT Humans are chronically exposed to mixtures of environmental contaminants. Exposure to endocrine‐disrupting chemicals (EDCs) contributes to increased health impairment observed globally. This study aimed to evaluate the endocrine‐disruptive and oxidative stress potential of a human‐relevant, complex chemical mixture in vitro.
Josefin Engelhardt +5 more
wiley +1 more source
Retinoic Acid Receptor Is a Novel Therapeutic Target for Postoperative Cognitive Dysfunction. [PDF]
Bao Y +12 more
europepmc +1 more source
Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis [PDF]
Shaun Mahony +5 more
openalex +1 more source

