Results 191 to 200 of about 357,868 (360)

Retinoic acid receptor structures: the journey from single domains to full-length complex. [PDF]

J Mol Endocrinol, 2022
Rastinejad F.
europepmc   +1 more source

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

Nature, 1992
S. Kliewer, K. Umesono, D. Mangelsdorf, R. Evans   +3 more
semanticscholar   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Retinoic Acid Receptor β Expression and Growth Inhibition of Gynecologic Cancer Cells by the Synthetic Retinoid N-(4-Hydroxyphenyl) Retinamide [PDF]

, 1998
Anita L. Sabichi, Denver T. Hendricks, Mary A. Bober, Michael J. Birrer   +3 more
openalex   +1 more source

Development of the retinoic acid receptor alpha-specific antagonist YCT-529 for male contraception: A brief review. [PDF]

Contraception
Shi R, Wolgemuth DJ, Georg GI.
europepmc   +1 more source

Timeline of Developmental Defects Generated upon Genetic Inhibition of the Retinoic Acid Receptor Signaling Pathway. [PDF]

Biomedicines, 2023
Teletin M, Mark M, Wendling O, Vernet N, Féret B, Klopfenstein M, Herault Y, Ghyselinck NB.   +7 more
europepmc   +1 more source

3D Quantification of Viral Transduction Efficiency in Living Human Retinal Organoids

Small Methods, EarlyView.
Optimization of viral vectors and their testing in human tissue is crucial to gene therapy development. Conventional technologies to assess virus transduction either lack spatial or temporal information. Here, spatiotemporal mapping of virus transduction in living retinal tissue is introduced, levering fluorescence imaging and machine learning‐based ...
Teresa S. Rogler, Katja A. Salbaum, Achim T. Brinkop, Selina M. Sonntag, Rebecca James, Elijah R. Shelton, Alina Thielen, Roland Rose, Sabrina Babutzka, Thomas Klopstock, Stylianos Michalakis, Friedhelm Serwane   +11 more
wiley   +1 more source

Inverse agonists of retinoic acid receptor/retinoid X receptor signaling as lineage-specific antitumor agents against human adenoid cystic carcinoma. [PDF]

J Natl Cancer Inst, 2023
Viragova S, Aparicio L, Palmerini P, Zhao J, Valencia Salazar LE, Schurer A, Dhuri A, Sahoo D, Moskaluk CA, Rabadan R, Dalerba P.   +10 more
europepmc   +1 more source

Single‐cell spatial transcriptomic sequencing and machine learning models uncover molecular mechanisms and diagnostic biomarkers of Peyronie's disease formation in rats

VIEW, EarlyView.
Peyronie's disease (PD) is a common male reproductive system disorder. The exact etiology of PD remains unclear. This study aimed to investigate molecular and cellular changes in PD using single‐cell spatial transcriptomics. Abstract Peyronie's disease (PD), commonly known as penile induration, is a prevalent male reproductive system disorder with ...
Keyuan Lou, Qiancheng Mao, Junpeng Chi, Jiankun Zhang, Hao Guo, Jitao Wu, Yuanshan Cui   +6 more
wiley   +1 more source

Cardiac compartment-specific overexpression of a modified retinoic acid receptor produces dilated cardiomyopathy and congestive heart failure in transgenic mice. [PDF]

, 1997
Melissa C. Colbert, D. Greg Hall, Thomas R. Kimball, Sandra A. Witt, John N. Lorenz, Michael Kirby, Timothy E. Hewett, Raisa Klevitsky, Jeffrey Robbins   +8 more
openalex   +1 more source