Results 211 to 220 of about 349,317 (300)

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang, Tu Huang, Yi‐hang Hao, Min Zheng, Xin‐hua Liang   +4 more
wiley   +1 more source

Anti-DNA Damage Mechanisms and the Role of Carotenoids, Vitamin A, and Its Derivatives. [PDF]

Nutrients
Kołodziejczyk AM, Karwowski B.
europepmc   +1 more source

The gene encoding human retinoic acid-receptor-related orphan receptor α is a target for hypoxia-inducible factor 1

, 2004
Caroline Chauvet, Brigitte Bois-Joyeux, Edurne Berra, Jacques Pouysségur, Jean-Louis Danan   +4 more
openalex   +2 more sources

Activation of Retinoic Acid Receptors by Dihydroretinoids

Molecular Pharmacology, 2009
Alexander R Moise, Susana Álvarez, Marta Domínguez, R. Álvarez, M. Golczak, Glenn P. Lobo, J. von Lintig, Á. D. De Lera, K. Palczewski   +8 more
semanticscholar   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Interactive Effects of Vitamin A and All-Trans Retinoic Acid on Growth Performance, Intestinal Health, and Plasma Metabolomics of Broiler Chickens. [PDF]

Animals (Basel)
Guo S, Xiong Y, He L, Yan J, Li P, Li C, Ding B.   +6 more
europepmc   +1 more source

Ligand specificities of recombinant retinoic acid receptors RAR alpha and RAR beta.

Biochemical Journal, 1990
M. Crettaz, A. Baron, G. Siegenthaler, W. Hunziker   +3 more
semanticscholar   +1 more source

Selective Promotion of Retinal Organoid Attachment and Differentiation by Amine‐ and Hydroxyl‐Modified Surfaces

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
Engineered biomaterial interfaces critically control retinal organoid development. This study examines how surface modifications (amine, hydroxyl, phenyl, and methyl groups) dictate organoid response. Hydrophilic surfaces markedly increase migration and foster retinal ganglion cell differentiation.
Luis Marcos, Charlie Hall, Eric J. Hill, Samantha L. Wilson, Paul Roach   +4 more
wiley   +1 more source

Bexarotene signaling in human B and T lymphocytes induces gut-homing receptor expression. [PDF]

Front Immunol
Kaiser S, Suhrkamp I, He J, Helf C, Sadik CD, Weichenthal M, Heine G.   +6 more
europepmc   +1 more source

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li, Lili Qiao, Xinquan Liang, Yingying Zhang, Ning Liang, Jian Xie, Guodong Deng, Yuying Hao, Pingping Hu, Xue Wu, Fangjie Ding, Can Feng, Yiming Mu, Jiandong Zhang   +13 more
wiley   +1 more source