Dimerization interfaces of thyroid hormone, retinoic acid, vitamin D, and retinoid X receptors
Evan D. Rosen+2 more
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Signaling by Tyrosine Kinases Negatively Regulates the Interaction between Transcription Factors and SMRT (Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor) Corepressor [PDF]
Suk-Hyun Hong+2 more
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Organ Specificity and Commonality of Epigenetic Aging in Low‐ and High‐Running Capacity Rats
Cardiorespiratory fitness (CRF) is not associated with epigenetic clocks, including newly developed ones. On the other hand, CRF is associated with global methylation profiles and promoter methylation in organ‐specific and organ‐common manner. ABSTRACT Epigenetic drift, which is gradual age‐related changes in DNA methylation patterns, plays a ...
Takuji Kawamura+15 more
wiley +1 more source
Inhibition of Retinoic Acid Receptor Function and Retinoic Acid-regulated Gene Expression in Mouse Melanoma Cells by Calreticulin [PDF]
Dinakar Desai+3 more
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Severe short‐term energy restriction in adults with prediabetes led to a significant reduction in circulating proteins linked to inflammation, senescence, and protein turnover. These changes, partly mediated by extracellular vesicles, suggest systemic dietary‐induced benefits beyond glycemic control, including improved aging biomarkers.
Maria Lastra Cagigas+16 more
wiley +1 more source
Ligand Induction of Retinoic Acid Receptors Alters an Acute Infection by Murine Cytomegalovirus [PDF]
Ana Angulo+3 more
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Abstract Background Imatinib and dasatinib are tyrosine kinase inhibitors (TKIs) increasingly used to treat several diseases in both children and adults at fertile age. We have previously shown that imatinib has adverse effects on developing testis, and imatinib‐treated male patients have been reported to have reduced sperm counts.
Anna Eggert+10 more
wiley +1 more source
Retinoic Acid Receptors and Binding Proteins in Human Skin
James T. Elder+7 more
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Retinoic Acid Receptor Expression Abnormalities in Lung Cancer: Important Clues or Major Obstacles? [PDF]
J D Minna, David J. Mangelsdorf
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