Results 201 to 210 of about 121,956 (356)

Role for the liver X receptor agonist 22‐ketositosterol in preventing disease progression in an Alzheimer's disease mouse model

British Journal of Pharmacology, Volume 182, Issue 16, Page 3744-3766, August 2025.
Background and Purpose Liver X receptors (LXRs) are promising therapeutic targets for alleviating Alzheimer's disease (AD) symptoms. We assessed the impact of the semi‐synthetic LXR agonist 22‐ketositosterol on disease progression in an AD mouse model.
Nikita Martens, Na Zhan, Sammie C. Yam, Marcella Palumbo, Lorenzo Pontini, Frank P. J. Leijten, Leonie van Vark‐van der Zee, Gardi Voortman, Silvia Friedrichs, Albert Gerding, Maura Marinozzi, Johan W. Jonker, Folkert Kuipers, Dieter Lütjohann, Tim Vanmierlo, Monique T. Mulder   +15 more
wiley   +1 more source

Therapeutic Uses of Retinol and Retinoid-Related Antioxidants. [PDF]

Molecules
Vašková J, Stupák M, Vidová Ugurbaş M, Židzik J, Mičková H.   +4 more
europepmc   +1 more source

Biochemical characterization of the retinoid isomerase system of the eye.

, 1987
Paul S. Bernstein, Wing‐Cheung Law, Robert R. Rando   +2 more
openalex   +1 more source

Phosphorylation enhances the target gene sequence-dependent dimerization of thyroid hormone receptor with retinoid X receptor. [PDF]

, 1994
Manoj K. Bhat, K Ashizawa, Sheue-yann Cheng   +2 more
openalex   +1 more source

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.

Proceedings of the National Academy of Sciences of the United States of America, 1993
H. Keller, C. Dreyer, J. Medin, A. Mahfoudi, K. Ozato, W. Wahli   +5 more
semanticscholar   +1 more source

Artemisinins in autoimmune diseases: effects and mechanisms in systemic lupus erythematosus and rheumatoid arthritis

British Journal of Pharmacology, Volume 182, Issue 15, Page 3411-3427, August 2025.
Abstract Autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) result from immune self‐tolerance loss, causing tissue damage. Standard treatments targeting late‐stage inflammation often have serious side effects. Artemisinin, known for its antimalarial properties, shows potential immunomodulatory effects.
Fanchao Zhou, Guoming Li, Ruixiang Tan, Guodong Wu, Changsheng Deng   +4 more
wiley   +1 more source

Identification of a Non-Retinoid Opsin Ligand Through Pharmacophore-Guided Virtual Screening-A Novel Potential Rhodopsin-Stabilizing Compound. [PDF]

Molecules
Di Stefano M, Ghilardi M, Poles C, Piazza L, Demontis GC, Poli G, Tuccinardi T, Macchia M.   +7 more
europepmc   +1 more source

Cyclic AMP, Glucocorticoid, and Retinoid Modulation of in Vitro Keratinocyte Growth

, 1983
Cynthia L. Marcelo, John M. Tomich
openalex   +1 more source

Effect of retinoid status on α, β and γ retinoic acid receptor mRNA levels in various rat tissues [PDF]

, 1992
Shigeaki Kato, Hiroshi Mano, T Kumazawa, Yukihiro Yoshizawa, Ryotaro Kojima, Shoichi Masushige   +5 more
openalex   +1 more source

A Case Report of Generalization of Localized Actinic Granuloma, an Unusual Diffuse Presentation Not Responding to Tofacitinib

Clinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT Actinic granuloma (AG), a rare and idiopathic skin condition primarily affecting middle‐aged and elderly individuals, is known for its persistent, asymptomatic annular plaques appearing on sun‐exposed areas. This report details the case of a 48‐year‐old diabetic male farmer with a rare presentation of generalized AG. The patient's lesions were
Saman Al‐Zahawi, Alireza Ghanadan, Fatemeh Saberi   +2 more
wiley   +1 more source