Results 241 to 250 of about 131,717 (361)

RPE65 is the isomerohydrolase in the retinoid visual cycle.

Proceedings of the National Academy of Sciences of the United States of America, 2005
G. Moiseyev, Ying Chen, Yusuke Takahashi, Bill X. Wu, Jian-xing Ma   +4 more
semanticscholar   +1 more source

Small-Molecule Ligands of Rhodopsin and Their Therapeutic Potential in Retina Degeneration. [PDF]

Int J Mol Sci
Pashandi Z, Jastrzebska B.
europepmc   +1 more source

Using an Unbiased Coexpression Network to Reveal Cross‐Talking Pathways of Phosphoinositide‐3‐Kinase Regulatory Subunit 1 in Skin Aging and Rejuvenation

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Mechanistic pathways of PIK3R1 in skin aging and rejuvenation were analyzed by bioinformatics approach and Gene Expression Omnibus database. Compared with young skin, PIK3R1 was differentially expressed in aged and IPL rejuvenated skin. Coexpression and network analyses revealed that PIK3R1 jointly participated in skin aging and rejuvenation via PI3K ...
Zhike Zhou, Sha Sha, Xiangnan Zhou, Chundi He, Ting Xiao, Yan Wu, Fenqin Chen, Le Qu, Hong‐Duo Chen   +8 more
wiley   +1 more source

Development of retinoid nuclear receptor pathway antagonists through targeting aldehyde dehydrogenase 1A3. [PDF]

iScience
Esposito M, Fang C, Wei Y, Pozzan A, Beato C, Su X, Hutton JE, Reed T, Hang X, Perini ED, Wang W, Cheng X, Pan Y, Yu J, Kane M, Manoharan M, Proudfoot J, Cristea IM, Kang Y.   +18 more
europepmc   +1 more source

Proximal Tubule‐Specific Genetic Deficiency of PPARα Worsens Systemic Lipid and Glucose Metabolism During Fasting

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Proximal tubule‐specific PPARα knockout mouse (PPARαΔKPT) showed decreased lipid and glucose metabolism in the kidney during fasting. Metabolism in the other organs was increased, presumably as a means of compensating for the impaired kidney metabolism.
Daiki Aomura, Takayuki Nimura, Kosuke Yamaka, Yosuke Yamada, Makoto Harada, Takero Nakajima, Takefumi Kimura, Koji Hashimoto, Hiroyuki Kanno, Motoko Yanagita, Frank J. Gonzalez, Naoki Tanaka, Yuji Kamijo   +12 more
wiley   +1 more source

A Rare Familial Case of Harlequin Ichthyosis in an Infant of a Diabetic Mother: A Diagnostic and Management Challenge in Low and Middle Income Settings. [PDF]

Clin Case Rep
Zaeem M, Hassan AHMU, Javaid MH, Usman M, Ahmed M, Naveed MU, Al Aboud MY.   +6 more
europepmc   +1 more source

Retinol-Binding Protein 4 and Its Membrane Receptor STRA6 Control Adipogenesis by Regulating Cellular Retinoid Homeostasis and Retinoic Acid Receptor α Activity

Molecular and Cellular Biology, 2013
M. Muenzner, N. Tuvia, C. Deutschmann, Nicole Witte, Alexander Tolkachov, Atijeh Valai, Andrea Henze, L. Sander, J. Raila, M. Schupp   +9 more
semanticscholar   +1 more source

Low satisfaction with medical care among patients with hidradenitis suppurativa: A multicenter study

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 2, Page e95-e99, February 2026.
Kerstin Wolk, Giorgia Cugno, Georgios Kokolakis, Sylke Schneider‐Burrus, Dagmar Wilsmann‐Theis, Katharina Assaf, Rotraut Moessner, Christian Kromer, Falk G. Bechara, Nessr Abu Rached, Wiebke K. Peitsch, Lisa C. Schneider, Andreas Happ, Valentina Siddi, Diana Kubitzki, Durdana Groß, Markus Friedrich, Staffan Vandersee, Khusru Asadullah, Robert Sabat   +19 more
wiley   +1 more source

From variant of unknown significance to actionable diagnosis: Stepwise interpretation of a novel <i>KRT2</i> variant in superficial epidermolytic ichthyosis with excellent retinoid response. [PDF]

JAAD Int
Bobica AC, Moussa S, Ouchene L, Udupa M, BinJadeed H, Bashihab R, Misiewicz Z, Grönroos L, Powell J, Chergui M, Marino TC, Foulkes WD, Netchiporouk E.   +12 more
europepmc   +1 more source

Reduced Esterification Rather Than Increased Hydrolysis Is Causative for Loss of Hepatic Retinoids Upon CCl₄-Induced Liver Injury. [PDF]

Liver Int
Wagner C, Košić K, Bulfon D, Breithofer J, Jamnik A, Zitta C, Horvat P, Bilweis K, Schupp M, Zimmermann R, Taschler U, Lass A.   +11 more
europepmc   +1 more source