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Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine

open access: yesNature Communications, 2020
Retinoids regulate a wide spectrum of cellular functions from the embryo throughout adulthood, including cell differentiation, metabolic regulation, and inflammation. These traits make retinoids very attractive molecules for medical purposes. In light of
Raquel Ferreira   +2 more
exaly   +2 more sources
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Retinoids

Current Opinion in Oncology, 1993
This review highlights recent advances in understanding the mode of action of retinoids at the level of molecular and cellular biology in relation to the new clinical results achieved with retinoids in various malignancies. All-trans-retinoic acid has been established in the clinic as a first-line differentiation therapy for acute promyelocytic ...
E E, Holdener, W, Bollag
  +7 more sources

Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2008
Artur V Cideciyan   +2 more
exaly   +2 more sources

Retinoid Signaling Determines Germ Cell Fate in Mice

Science, 2006
Josephine Bowles   +2 more
exaly   +2 more sources

Retinoid Receptors

Dermatologic Clinics, 2007
"Retinoid" refers to the naturally occurring compounds with vitamin A activity and to synthetic analogues of retinol. Retinoids are key regulators of differentiation, proliferation, and inflammation. Their successful use in the treatment of various skin diseases and neoplasias has revolutionized the practice of dermatology as well as oncology.
Batya B, Davidovici   +2 more
openaire   +2 more sources

Retinoid pathway and cancer therapeutics

open access: yesAdvanced Drug Delivery Reviews, 2010
Yu-Jui Yvonne Wan
exaly   +2 more sources

Retinoid Specificity of Interphotoreceptor Retinoid-Binding Protein

Biochemistry, 1994
Interphotoreceptor retinoid-binding protein (IRBP), the predominant protein in the interphotoreceptor matrix of retina, has been implicated in transfer of retinoids between retinal pigment epithelium and photoreceptor cells. In this work, the interactions of several retinoids with IRBP were studied in order to clarify whether the protein displays ...
Y, Chen, N, Noy
openaire   +2 more sources

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