Results 301 to 310 of about 121,956 (356)

Sustained improvement of elastosis perforans serpiginosa after isotretinoin therapy

open access: yesJAAD Case Reports
Sasan D. Noveir, BA   +2 more
doaj  
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Severe psoriasis--oral therapy with a new retinoid.

Dermatologica, 1978
Ro 10-9359 is a retinoic acid derivative, selected for study because of a better tolerance than retinoic acid, shown in animal experiments. Doses of 25 mg b.i.d., 25 mg t.i.d. and 50 mg b.i.d. were administered orally to 27 patients suffering from severe
T. Fredriksson, U. Pettersson
semanticscholar   +1 more source

Retinoids

Current Opinion in Oncology, 1993
This review highlights recent advances in understanding the mode of action of retinoids at the level of molecular and cellular biology in relation to the new clinical results achieved with retinoids in various malignancies. All-trans-retinoic acid has been established in the clinic as a first-line differentiation therapy for acute promyelocytic ...
E E, Holdener, W, Bollag
openaire   +2 more sources

Alcohol and Retinoids

Alcoholism: Clinical and Experimental Research, 2001
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Hirokazu Yokoyama and David Crabb. The presentations were (1) Roles of vitamin A, retinoic acid, and retinoid receptors in the expression of liver ALDH2, by J. Pinaire, R. Hasanadka, M. Fang, and David W.
Hidekazu Tsukamoto   +20 more
openaire   +3 more sources

Retinoids

2015
Retinoids are analogs of vitamin A that exert multiple effects on cellular differentiation and proliferation, the immune system, and embryonic development. A thorough understanding of their mechanisms of action, formulations, administration, and potential adverse effects enables dermatologists to effectively and safely treat patients with a variety of ...
Sorg, Olivier, Saurat, Jean-Hilaire
openaire   +4 more sources

Overview of retinoid metabolism and function.

Journal of Neurobiology, 2006
Retinoids (vitamin A) are crucial for most forms of life. In chordates, they have important roles in the developing nervous system and notochord and many other embryonic structures, as well as in maintenance of epithelial surfaces, immune competence, and
R. Blomhoff, H. Blomhoff
semanticscholar   +1 more source

Nuclear retinoid receptors and the transcription of retinoid-target genes.

Gene, 2004
The pleiotropic effects of retinoids are mediated by nuclear retinoid receptors (RARs and RXRs) which are ligand-activated transcription factors. In response to retinoid binding, RAR/RXR heterodimers undergo major conformational changes and orchestrate the transcription of specific gene networks, through binding to specific DNA response elements and ...
J. Bastien, C. Rochette-Egly
semanticscholar   +4 more sources

The multifaceted nature of retinoid transport and metabolism.

Hepatobiliary surgery and nutrition, 2014
Since their discovery over a century ago, retinoids have been the most studied of the fat-soluble vitamins. Unlike most vitamins, retinoids are stored at relatively high concentrations in the body to buffer against nutritional insufficiency.
Yang Li   +2 more
semanticscholar   +1 more source

Retinoids in cosmeceuticals

Dermatologic Therapy, 2006
Retinoids are natural and synthetic vitamin A derivatives. They are lipophilic molecules and easily penetrate the epidermis. Their biologically active forms can modulate the expression of genes involved in cellular differentiation and proliferation. Retinoic acid (tretinoin), its 13-cis isomer isotretinoin, as well as various synthetic retinoids are ...
Olivier Sorg   +3 more
openaire   +3 more sources

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