Results 71 to 80 of about 6,100,826 (198)

S1 Guideline: Therapy of generalized pustular psoriasis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The S1 guideline “Therapy of generalized pustular psoriasis (GPP)” is a German guideline developed in accordance with the criteria of the AWMF. The full version addresses clinical presentation, pathogenesis, diagnosis and differential diagnosis, comorbidities, and therapy.
Rotraut Mößner, Neda Cramer, Sascha Gerdes, Ulrike Hüffmeier, Andreas Körber, Kai Krause, Christian Kromer, Katharina Antonia Langen, Sandra Philipp, Knut Schäkel, Michael P. Schön, Michael Schultheis, Lukas Sollfrank, Petra Staubach, Michael Sticherling, Johannes Wohlrab, Dagmar Wilsmann‐Theis, Cornelia Paul   +17 more
wiley   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

Role of Retinoid X Receptors (RXRs) and dietary vitamin A in Alzheimer's disease: Evidence from clinicopathological and preclinical studies. [PDF]

Neurobiol Dis, 2021
Biyong EF, Tremblay C, Leclerc M, Caron V, Alfos S, Helbling JC, Rodriguez L, Pernet V, Bennett DA, Pallet V, Calon F.   +10 more
europepmc   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

International Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Lycopene-derived bioactive retinoic acid receptors/retinoid-X receptors-activating metabolites may be relevant for lycopene's anti-cancer potential

, 2013
Dietary consumption of tomato products and especially the red tomato pigment lycopene has been associated with lower risk of cancer. New evidence is emerging toward metabolic pathways mediating the anti-cancer activities of lycopene.
Kasiri, Y., Garcia, A.L., Eszter Birta, Ralph Rühl, Gabriella Béke, Emőke-Márta Bartók, Bartók, E., Béke, G., Aydemir, G., Birta, E., Gamze Aydemir, Yasamin Kasiri, Ada L. Garcia, Rühl, R.   +13 more
core   +1 more source

Enhancing scar appearance: Results from a cosmetic clinical study on dexpanthenol‐containing silicone gel and massage ball in adults and children

International Journal of Cosmetic Science, EarlyView.
This cosmetic clinical study demonstrates improvements in scar appearance associated with the use of a dexpanthenol‐containing silicone gel with an integrated massage ball in adults and children. Abstract Objective To evaluate changes in scar appearance and tolerability associated with 8 weeks of use of a test product comprising a topical dexpanthenol ...
Erwan Peltier, Raffaella de Salvo, Natascha Hennighausen, Katrin Unbereit   +3 more
wiley   +1 more source

Targeting retinoid receptors with dysregulated microNRAs in pancreatic duct adenocarcinoma [PDF]

, 2018
Retinoid (i.e., vitamin A, all-trans retinoic acid and other synthetic derivatives of vitamin A) induce cell differentiation and growth via the interaction of retinoid receptors in various normal and malignant cells.
Yin, Shuai
core   +1 more source

Identification of Bexarotene as a PPARγ Antagonist with HDX

PPAR Research, 2015
The retinoid x receptors (RXRs) are the pharmacological target of Bexarotene, an antineoplastic agent indicated for the treatment of cutaneous T cell lymphoma (CTCL).
David P. Marciano, Dana S. Kuruvilla, Bruce D. Pascal, Patrick R. Griffin   +3 more
doaj   +1 more source

Nuclear Receptors Are Differentially Expressed and Activated in KAIMRC1 Compared to MCF7 and MDA-MB231 Breast Cancer Cells

Molecules, 2019
We recently established a KAIMRC1 cell line that has unique features compared to the known breast cancer cell lines, MCF7 and MDA-MB231. To characterize it further, we investigated the expression profile of nuclear receptors and their respective co ...
Atef Nehdi, Rizwan Ali, Alshaimaa Alhallaj, Hajar Alzahrani, Nosaibah Samman, Abdullah Mashhour, Omar Baz, Tlili Barhoumi, Bandar Alghanem, Abdullatif Khan, Lolwah Alriyees, Mohamed Boudjelal   +11 more
doaj   +1 more source

Lignan‐rich Norway spruce (Picea abies) resin extract exhibits anti‐inflammatory, skin‐regenerative and anti‐acne effects: In vitro, in silico, biocompatibility and exploratory clinical findings

International Journal of Cosmetic Science, EarlyView.
GA text A 30% Picea abies resin extract cream combined antimicrobial, anti‐inflammatory and early pro‐repair activities relevant to acne‐prone skin. The formulation showed strong activity against Cutibacterium acnes, reduced inflammatory cytokines and demonstrated promising tolerability and efficacy in an exploratory in‐use study. Abstract Objective To
Simone Parrotta, Kamilla Yamileva, Laura Punakallio, Maryam Ghanbarirad, Evgen Multia   +4 more
wiley   +1 more source