Results 101 to 110 of about 77,321 (327)
On a dynamic reaction-diffusion mechanism: The spatial patterning of teeth primordia in the alligator [PDF]
It is now well established both theoretically and, more recently, experimentally, that steady-state spatial chemical concentration patterns can be formed by a number of specific reaction–diffusion systems.
Kulesa, P. M., Murray, J. D.
core +1 more source
Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate. [PDF]
The light absorbing chromophore in opsin visual pigments is the protonated Schiff base of 11-cis-retinaldehyde (11cRAL). Absorption of a photon isomerizes 11cRAL to all-trans-retinaldehyde (atRAL), briefly activating the pigment before it dissociates ...
Fain, Gordon L +6 more
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Therapeutic Options for IgA Pemphigus in Patients Refractory to Dapsone
ABSTRACT IgA pemphigus is a rare autoimmune blistering disorder with limited therapeutic guidance available due to its rarity and complex presentation. This comprehensive analysis evaluates the therapeutic outcomes of 67 published patients, emphasising the significant role of dapsone as the first‐line treatment.
Lorenz Frasheri +2 more
wiley +1 more source
Differential effects of steroids and retinoids on bovine myelopoiesis in vitro [PDF]
Pregnancy and parturition are associated with physiological changes caused by steroid hormones. Alterations in number, maturity, and function of polymorphonuclear leukocytes observed in dairy cows at parturition suggest a common causative relationship ...
Burvenich, Christian +3 more
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Early Acitretin Therapy in a Patient With Harlequin Ichthyosis
ABSTRACT Harlequin ichthyosis (HI) is a rare, severe congenital disorder of keratinization caused by pathogenic variants in the ABCA12 gene resulting in thick, hyperkeratotic plates, deep fissures, and characteristic facial and limb abnormalities.
Orasa Sukmark +2 more
wiley +1 more source
Although the administration of retinoids represents an important part of treatment for children suffering from high-risk neuroblastomas, approximately 50% of these patients do not respond to this therapy or develop resistance to retinoids during ...
Viera Dobrotkova +6 more
doaj +1 more source
Emerging role of nuclear factor erythroid 2-related factor 2 in the mechanism of action and resistance to anticancer therapies [PDF]
Nuclear factor E2-related factor 2 (NRF2), a transcription factor, is a master regulator of an array of genes related to oxidative and electrophilic stress that promote and maintain redox homeostasis. NRF2 function is well studied in in vitro, animal and
Deeni, Yusuf Y. +3 more
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Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety
Aging of skin is an intricate biological process consisting of two types. While intrinsic or chronological aging is an inevitable process, photoaging involves the premature aging of skin occurring due to cumulative exposure to ultraviolet radiation ...
S. Mukherjee +5 more
semanticscholar +1 more source
Abstract Background In moderate‐to‐severe psoriasis, residual lesions can be defined as “psoriasis lesions that persist despite well‐managed treatment, and which do not necessarily justify intensification or a change in treatment.” Residual lesions are accepted by guidelines and clinical trials.
Emmanuel Mahé +4 more
wiley +1 more source
Nutritional factors associated with acne vulgaris [PDF]
Acne Vulgaris is a common dermatological condition defined as a chronic inflammatory dermatosis of the pilosebaceous unit that affects more than 17 million Americans.^1 Although it is not considered a dangerous condition, it may drastically impair ...
Patton, Elaura Elizabeth
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