Results 101 to 110 of about 77,321 (327)

On a dynamic reaction-diffusion mechanism: The spatial patterning of teeth primordia in the alligator [PDF]

open access: yes, 1996
It is now well established both theoretically and, more recently, experimentally, that steady-state spatial chemical concentration patterns can be formed by a number of specific reaction–diffusion systems.
Kulesa, P. M., Murray, J. D.
core   +1 more source

Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate. [PDF]

open access: yes, 2017
The light absorbing chromophore in opsin visual pigments is the protonated Schiff base of 11-cis-retinaldehyde (11cRAL). Absorption of a photon isomerizes 11cRAL to all-trans-retinaldehyde (atRAL), briefly activating the pigment before it dissociates ...
Fain, Gordon L   +6 more
core   +1 more source

Therapeutic Options for IgA Pemphigus in Patients Refractory to Dapsone

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT IgA pemphigus is a rare autoimmune blistering disorder with limited therapeutic guidance available due to its rarity and complex presentation. This comprehensive analysis evaluates the therapeutic outcomes of 67 published patients, emphasising the significant role of dapsone as the first‐line treatment.
Lorenz Frasheri   +2 more
wiley   +1 more source

Differential effects of steroids and retinoids on bovine myelopoiesis in vitro [PDF]

open access: yes, 2004
Pregnancy and parturition are associated with physiological changes caused by steroid hormones. Alterations in number, maturity, and function of polymorphonuclear leukocytes observed in dairy cows at parturition suggest a common causative relationship ...
Burvenich, Christian   +3 more
core   +1 more source

Early Acitretin Therapy in a Patient With Harlequin Ichthyosis

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Harlequin ichthyosis (HI) is a rare, severe congenital disorder of keratinization caused by pathogenic variants in the ABCA12 gene resulting in thick, hyperkeratotic plates, deep fissures, and characteristic facial and limb abnormalities.
Orasa Sukmark   +2 more
wiley   +1 more source

Prediction of neuroblastoma cell response to treatment with natural or synthetic retinoids using selected protein biomarkers.

open access: yesPLoS ONE, 2019
Although the administration of retinoids represents an important part of treatment for children suffering from high-risk neuroblastomas, approximately 50% of these patients do not respond to this therapy or develop resistance to retinoids during ...
Viera Dobrotkova   +6 more
doaj   +1 more source

Emerging role of nuclear factor erythroid 2-related factor 2 in the mechanism of action and resistance to anticancer therapies [PDF]

open access: yes, 2019
Nuclear factor E2-related factor 2 (NRF2), a transcription factor, is a master regulator of an array of genes related to oxidative and electrophilic stress that promote and maintain redox homeostasis. NRF2 function is well studied in in vitro, animal and
Deeni, Yusuf Y.   +3 more
core   +3 more sources

Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety

open access: yesClinical Interventions in Aging, 2006
Aging of skin is an intricate biological process consisting of two types. While intrinsic or chronological aging is an inevitable process, photoaging involves the premature aging of skin occurring due to cumulative exposure to ultraviolet radiation ...
S. Mukherjee   +5 more
semanticscholar   +1 more source

Residual Disease in Adult Psoriasis‐Treated Patients: Frequency, Clinical Aspects, and Management. A Survey Among Dermatologists

open access: yesJEADV Clinical Practice, EarlyView.
Abstract Background In moderate‐to‐severe psoriasis, residual lesions can be defined as “psoriasis lesions that persist despite well‐managed treatment, and which do not necessarily justify intensification or a change in treatment.” Residual lesions are accepted by guidelines and clinical trials.
Emmanuel Mahé   +4 more
wiley   +1 more source

Nutritional factors associated with acne vulgaris [PDF]

open access: yes, 2016
Acne Vulgaris is a common dermatological condition defined as a chronic inflammatory dermatosis of the pilosebaceous unit that affects more than 17 million Americans.^1 Although it is not considered a dangerous condition, it may drastically impair ...
Patton, Elaura Elizabeth
core   +1 more source

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