Results 111 to 120 of about 31,233 (276)

A Pericyclic Cascade to the Stereocontrolled Synthesis of 9-cis-Retinoids

, 2016
A domino reaction that is pericyclic in nature is thought to be triggered upon treatment of alkenynol 10 with arylsulfenyl chlorides. The process comprises an ordered sequence of sigmatropic rearrangements:  a reversible [2,3]-allyl sulfenate to allyl ...
Alicia Torrado (1479391), Angel R. de Lera (1811737), Beatriz Iglesias (2216716), Susana López (606291)   +3 more
core   +1 more source

Ropeginterferon‐α2b in mycosis fungoides and Sézary syndrome: Safety and efficacy in 41 patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Pegylated interferon‐α2a became the off‐label alternative for treating mycosis fungoides/Sézary syndrome (MF/SS) after non‐pegylated interferons were withdrawn. This study aimed to evaluate the safety and efficacy of ropeginterferon‐α2b in MF/SS. Patients and methods We performed a retrospective multicenter analysis at
Stefanie Porkert, Juliette M. Kersten, Rosanne Ottevanger, Hanna Schratter, Regina Fink‐Puches, Van Anh Nguyen, Farzaneh Sadeghyar, Johanna Latzka, Franz Trautinger, Magdalena Hoellwerth, Peter Koelblinger, Nicole Pfannschmidt, Nina Haering, Johannes Griss, Maarten H. Vermeer, Constanze Jonak   +15 more
wiley   +1 more source

Topical and Systemic Retinoids in the Management of Hidradenitis Suppurativa: A Comprehensive Literature Review

Dermatology and Therapy
Hidradenitis suppurativa (HS) is a debilitating chronic skin disorder characterized by painful inflammatory nodules, abscesses and sinus tracts involving intertriginous areas and has an adverse impact on patient quality of life. Over the past decade, the
Elisa Molinelli, Helena Gioacchini, Andrea Marani, Giulio Rizzetto, Daisy Gambini, Edoardo De Simoni, Annamaria Offidani, Oriana Simonetti   +7 more
doaj   +1 more source

Retinoids in scarless skin regeneration: from molecular mechanisms to therapeutic strategies

Frontiers in Cell and Developmental Biology
Scarless skin regeneration remains one of the most ambitious goals in regenerative medicine. Unlike fibrotic healing, which results in excessive collagen accumulation and functional impairment, true regeneration restores both the structural integrity and
Kang Wang, Kang Wang, Ziting Yang, Yunqi Ma, Yunqi Ma, Wenhui Liu, Guangshuai Li, Xuewen Xu, Qingfeng Li   +8 more
doaj   +1 more source

retinoids [PDF]

, 2014
Citation: 'retinoids' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.R05369 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Sythesis of retinoic acid analogues & investigations into their ability to induce stem cell differentation [PDF]

, 2009
Human embryogenesis and ensuing adult homeostasis are directed by the complex interplay of a wide range of exquisitely controlled signalling molecules and pathways. All-trans-retinoic acid (ATRA) is one such important hormone-like compound that regulates
Bridgens, Caroline Emma
core  

Navigating Treatments in Folliculitis Decalvans: A Comprehensive Systematic Review

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Folliculitis decalvans (FD) is a chronic neutrophilic cicatricial alopecia characterized by recurrent scalp inflammation, pustules, tufted hairs, and progressive permanent hair loss. Owing to its relapsing course and the absence of standardized treatment guidelines, therapeutic management remains challenging.
Imad Al‐naesan, Thomas Trafoier, Daniela Krepper, Johannes M. Giesinger, Florian Regensberger, Simone Cazzaniga, Pierre A. de de Viragh, Seyed M. Seyed Jafari   +7 more
wiley   +1 more source

Do topical retinoids cause acne to flare ?

, 2009
BACKGROUND: Guidelines support this use of topical retinoids as a fundamental part of acne treatment regimens. However, existing dogma holds that topical retinoids may initially worsen acne.
McCalin, Richard, MD, Yentzer, Brad A, Feldman, Steven R   +2 more
core   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source