Results 81 to 90 of about 31,233 (276)

Targeted Topical Delivery of Retinoids in the Management of Acne Vulgaris: Current Formulations and Novel Delivery Systems

Pharmaceutics, 2019
Acne vulgaris is a common inflammatory pilosebaceous condition that affects 80−90% of adolescents. Since the introduction of tretinoin over 40 years ago, topical retinoid products have been a mainstay of acne treatment.
Gemma Latter, Jeffrey E. Grice, Yousuf Mohammed, Michael S. Roberts, Heather A. E. Benson   +4 more
doaj   +1 more source

Toll‐Like Receptor 4 Signaling in Natural N‐Acylethanolamines and Derivative NAE‐Like Compounds: Mechanisms and Implications for Neuroimmune and Inflammatory Processes in a Systematic Search Approach

Phytotherapy Research, EarlyView.
ABSTRACT N‐acylethanolamines (NAEs) are endogenous fatty acid amides structurally related to the endocannabinoid anandamide and function as bioactive lipid mediators with broad regulatory roles in inflammation and neuroinflammation. Among pattern‐recognition receptors, Toll‐like receptor 4 (TLR4) occupies a central position in innate immune ...
Damiana Scuteri, Francesca Guida, Giacinto Bagetta, Sabatino Maione, Maria Tiziana Corasaniti, Morena Zusso   +5 more
wiley   +1 more source

Vitamin A - potential anticancer weapon

Journal of Education, Health and Sport
Introduction:  Vitamin A, one of the most popular vitamins that people usually associate with eye health or beautiful skin, also has many other functions and uses.
Natalia Aleksandra Popławska, Justyna Śliz, Marta Skorupska, Magdalena Joanna Czeczotka, Krzysztof Woźniak   +4 more
doaj   +1 more source

Retinol and Retinyl Palmitate in Foetal Lung Mice: Sexual Dimorphism

Critical Care Research and Practice, 2013
In this work, we evaluate the lung retinoids content to study the possible difference between male and female mice during prenatal development and to comprehend if the vitamin A metabolism is similar in both genders.
Olga Carvalho, Carlos Gonçalves
doaj   +1 more source

Systemic retinoids. What's new?

, 1998
Despite major advances in the molecular biology and pharmacology of retinoids, no new compound has been developed for systemic use. This article addresses some questions related to the indications of oral retinoids already on the market, e.g ...
Saurat JH
core   +1 more source

Integrative Bioinformatics, Experimental Validation, and Interpretable Machine Learning Reveal Oxyresveratrol‐Mediated Protection Against Cadmium‐Induced Lung Adenocarcinoma‐Related Transcriptional Dysregulation

Environmental Toxicology, EarlyView.
ABSTRACT Cadmium (Cd) is a toxic heavy metal strongly implicated in lung adenocarcinoma (LUAD) through mechanisms involving oxidative stress, epigenetic dysregulation, and chronic inflammation. This study aimed to identify Cd‐responsive genes associated with LUAD and to evaluate the protective effects of oxyresveratrol (O‐RES) against Cd‐induced ...
Murat Isıyel, Hamid Ceylan, Yeliz Demir
wiley   +1 more source

Retinoids: Novel Immunomodulators and tumor-suppressive agents?

, 2012
Retinoids play important roles in the transcriptional activity of normal, degenerative and tumor cells. Retinoid analogues may be promising therapeutic agents for the treatment of immune disorders as different as type I diabetes and Systemic Lupus ...
MR Carratù, C Marasco, G Mangialardi, MARASCO C., CARRATU', Maria Rosaria, A Vacca, VACCA, Angelo, MANGIALARDI G.   +7 more
core   +1 more source

Two Entities, One Patient

JEADV Clinical Practice, EarlyView.
Wael Zaina, Tomer Cohen, Judit Krausz, Michael Ziv, Roni P. Dodiuk‐Gad   +4 more
wiley   +1 more source

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

VIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore, Beatrice Pellegrini, Antonia Mancuso, Maria Chiara Cristiano, Salvatore Panza, Donatella Paolino   +5 more
wiley   +1 more source

Decreased Production of Tissue Plasminogen Activator in Endothelial Cells From Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Previous studies have demonstrated that chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by excessive fibrin deposition which is related to impaired production of tissue plasminogen activator(t‐PA) by epithelial cells.
Qian‐Qian Zhang, Chen Zhang, Jia‐Ni Chen, Fu‐Ying Cheng, Yi‐Zhang Wang, Shi‐Rui Xue, Huan Wang, De‐Hui Wang, Xi‐Cai Sun, Li Hu   +9 more
wiley   +1 more source