Results 61 to 70 of about 30,549 (287)

Hyperhidrosis: problems and solutions [PDF]

Vestnik Dermatologii i Venerologii
The functional role of sweating is not limited only to thermoregulation and excretion. There are other functions of it — the ability to enhance and maintain hydration and barrier function of the skin.
Stanislava Yu. Petrova, Vera I. Albanova, Konstantin S. Guzev   +2 more
doaj   +1 more source

Synthetic retinoids as potential antitumour agents

, 2005
The retinoids, natural or synthetic derivatives of vitamin A, exhibit a variety of biological effects that may have implications in cancer chemoprevention and therapy.
F. Zunino, S. Dallavalle, Sabrina Dallavalle, Franco Zunino   +3 more
core   +1 more source

Unraveling the Plasma Extracellular Vesicles Proteome: Predictors of Resistance in Immunotherapy of Advanced Melanoma

International Journal of Cancer, EarlyView.
ABSTRACT Despite substantial clinical benefit from immune checkpoint inhibitors (ICI), advanced melanoma remains challenging due to frequent treatment resistance. Resistance may be intrinsic (primary) or emerge over time (secondary). Biomarkers predicting distinct resistance phenotypes before therapy are lacking.
Julian Kött, Glenn Geidel, Carmen M. T. Roeper, Lucija Ačkar, Bente Siebels, Hannah Voß, Hartmut Schlüter, Michaela Schweizer, Kilian Müller, Alessandra Rünger, Tim Zell, Benjamin Deitert, Ali Zeinal‐Abedini, Isabel Heidrich, Stefan W. Schneider, Klaus Pantel, Daniel J. Smit, Christoffer Gebhardt   +17 more
wiley   +1 more source

Retinoids

, 2018
Retinoids are structural and functional analogues of vitamin A that exert multiple effects on cellular differentiation and proliferation, the immune system, and embryonic development Retinoic acid receptors (RARs) and retinoid X receptors (RXRs) are ...
Sorg, Olivier, Saurat, Jean-Hilaire
core   +1 more source

Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik, Asuman Deveci Ozkan, Tuğba Kotil, Nazan Deniz Yön   +3 more
wiley   +1 more source

INDEPENDENT ASSISTANTS AND PARTNERS OF RUSSIAN NATURAL RESEARCHERS ON THE ABROAD OF THE XIX-XX CENTURY

Разработка и регистрация лекарственных средств, 2019
The paper presents information about F.B. Schwabe and N. Zaklin, entrepreneurs of the late 19th and early 20th centuries who, through their labor and ingenuity, created the material and technical base that provided the development of various branches of ...
K. S. Guzev
doaj  

Transparent Surfactant‐Based Isotropic Systems for Topical Co‐Delivery of Hydrophilic and Lipophilic Actives for Striae Distensae

Journal of Surfactants and Detergents, EarlyView.
ABSTRACT Striae distensae are common dermal lesions that negatively affect skin appearance, and topical management remains limited by challenges related to skin deposition and residence time. Here, we developed transparent surfactant‐based isotropic systems for the topical co‐delivery of ascorbic acid (AA), retinoic acid (RA), and lavender essential ...
Claudiane Ayres Prochno, Anna Paula Brusamarello, Anna Cláudia Morais de Oliveira Capote, Thais Leticia Moreira da Silva, Gabriela Ruva Fagundes, Giovani Marino Favero, Marina Tolentino Marinho, Benjamim Melo de Carvalho, Priscileila Colerato Ferrari   +8 more
wiley   +1 more source

Retinoid Antagonists

YAKUGAKU ZASSHI, 1996
Retinoids, retinoic acid and its bioisosters, regulate many biological functions such as cell differentiation, proliferation and embryonic development in vertebrates, through binding to and activating their specific nuclear receptors. There are two classes of nuclear receptors for retinoids, retinoic acid receptors (RAR alpha, beta, gamma) and retinoid
H, Umemiya, H, Kagechika, H, Fukasawa, Y, Hashimoto, K, Shudo   +4 more
openaire   +3 more sources

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Retinoids in Embryonic Development

, 2020
Retinoids constitute a class of compounds chemically related to vitamin A [...
Schubert, Michael, Michael Schubert, Gibert, Yann, Yann Gibert   +3 more
core   +1 more source